Possible reversibility between epithelioid and sarcomatoid types of mesothelioma is independent of ERC/mesothelin expression

August 20, 2020 | Comments Off on Possible reversibility between epithelioid and sarcomatoid types of mesothelioma is independent of ERC/mesothelin expression

Respiratory Research 2020 July 16 [Link] Masataka Kojima, Kazunori Kajino, Shuji Momose, Nadila Wali, May Thinzar Hlaing, Bo Han, Liang Yue, Masaaki Abe, Tomoaki Fujii, Katsuhisa Ikeda, Okio Hino Abstract…

Testing for BAP1 loss and CDKN2A/p16 homozygous deletion improves the accurate diagnosis of mesothelial proliferations in effusion cytology

August 19, 2020 | Comments Off on Testing for BAP1 loss and CDKN2A/p16 homozygous deletion improves the accurate diagnosis of mesothelial proliferations in effusion cytology

Cancer Cytopathology 2020 July 17 [Link] Martin Chevrier, Sara E Monaco, Jacob A Jerome, Francoise Galateau-Salle, Andrew Churg, Sanja Dacic Abstract Background: A number of ancillary tests have been developed…

Progress in the understanding of the immune microenvironment and immunotherapy in malignant pleural mesothelioma

August 18, 2020 | Comments Off on Progress in the understanding of the immune microenvironment and immunotherapy in malignant pleural mesothelioma

Current Drug Targets 2020 July 18 [Link] Lei Cheng, Li Na, Xiao-Ling Xu, Wei-Min Mao Abstract Malignant pleural mesothelioma (MPM) is a remarkably aggressive thoracic malignancy with a limited survival…

Ganetespib in Combination with Pemetrexed-Platinum Chemotherapy in Patients with Pleural Mesothelioma (MESO-02): A Phase Ib Trial

August 17, 2020 | Comments Off on Ganetespib in Combination with Pemetrexed-Platinum Chemotherapy in Patients with Pleural Mesothelioma (MESO-02): A Phase Ib Trial

Clinical Cancer Research 2020 July 15 [Link] Dean A Fennell, Sarah Danson, Penella J Woll, Martin Forster, Denis Talbot, Jennifer Child, Laura Farrelly, Annabel Sharkey, Sara Busacca, Yenting Ngai, Allan…

Nucleolin and nucleophosmin expression patterns in pulmonary adenocarcinoma invading the pleura and in pleural malignant mesothelioma

August 14, 2020 | Comments Off on Nucleolin and nucleophosmin expression patterns in pulmonary adenocarcinoma invading the pleura and in pleural malignant mesothelioma

Thoracic Cancer 2020 July 16 [Link] Marek Masiuk, Piotr Waloszczyk, Magdalena Lewandowska, Ewa Dobak, Elzbieta Urasinska Abstract Background: Visceral pleural invasion (VPI) in adenocarcinoma of the lung is considered a…

Targeting SRC Family Kinases in Mesothelioma: Time to Upgrade

August 13, 2020 | Comments Off on Targeting SRC Family Kinases in Mesothelioma: Time to Upgrade

Cancers 2020 July 11 [Link] Paola Indovina, Iris Maria Forte, Francesca Pentimalli, Antonio Giordano Abstract Abstract: Malignant mesothelioma (MM) is a deadly tumor mainly caused by exposure to asbestos. Unfortunately,…

Mapping the Interactome of the Nuclear Heparan Sulfate Proteoglycan Syndecan-1 in Mesothelioma Cells

August 12, 2020 | Comments Off on Mapping the Interactome of the Nuclear Heparan Sulfate Proteoglycan Syndecan-1 in Mesothelioma Cells

Biomolecules 2020 July 11 [Link] Ashish Kumar-Singh, Jatin Shrinet, Malgorzata Maria Parniewska, Jonas Fuxe, Katalin Dobra, Anders Hjerpe Abstract Syndecan-1 (SDC1) is a cell surface heparan sulfate proteoglycan (HSPG), which…

Mitochondrial ROS Induce Partial Dedifferentiation of Human Mesothelioma via Upregulation of NANOG

August 11, 2020 | Comments Off on Mitochondrial ROS Induce Partial Dedifferentiation of Human Mesothelioma via Upregulation of NANOG

Antioxidants 2020 July 10 [Link] Filip Sedlic, Fran Seiwerth, Ana Sepac, Suncana Sikiric, Marina Cindric, Marija Milavic, Lovorka Batelja Vuletic, Marko Jakopovic, Sven Seiwerth Abstract The expression of pluripotency factors…

Verification of a blood based targeted proteomics signature for malignant pleural mesothelioma

August 10, 2020 | Comments Off on Verification of a blood based targeted proteomics signature for malignant pleural mesothelioma

Cancer Epidemiol Biomarkers, July 30, 2020 (Epub ahead of print) [Link] Ferdinando Cerciello, et.al. Abstract Background: We have verified a mass spectrometry (MS) based targeted proteomics signature for the detection…

Questioning the Prognostic Role of BAP-1 Immunohistochemistry in Malignant Pleural Mesothelioma: A Single Center Experience With Systematic Review and Meta-Analysis

July 10, 2020 | Comments Off on Questioning the Prognostic Role of BAP-1 Immunohistochemistry in Malignant Pleural Mesothelioma: A Single Center Experience With Systematic Review and Meta-Analysis

Lung Cancer 2020 June 21 [Link] Luca Cantini, Federica Pecci, Alberto Murrone, Marco Tomasetti, Cecilia Copparoni, Ilaria Fiordoliva, Francesca Morgese, Silvia Rinaldi, Paola Mazzanti, Corrado Rubini, Alessia Cimadamore, Francesca Barbisan,…

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