Causation
EWSR1::YY1 fusion positive peritoneal epithelioid mesothelioma harbors mesothelioma epigenetic signature: report of 3 cases in support of an emerging entity
Genes, Chromosomes & Cancer 2022 June 4 [Link] Josephine K Dermawan, Dianne Torrence, Cheng-Han Lee, Liliana Villafania, Kerry A Mullaney, Sara DiNapoli, Purvil Sukhadia, Ryma Benayed, Laetitia Borsu, Narasimhan P Agaram, Garrett M Nash, Brendan C Dickson, Jamal Benhamida, Cristina R Antonescu Abstract Mesothelioma is a rare, aggressive malignant neoplasm of mesothelial origin. A small…
Read MoreLung cancer and mesothelioma risks in a prospective cohort of workers with asbestos-related lung or pleural diseases
American Journal of Industrial Medicine 2022 June 1 [Link] Dirk Taeger, Katharina Wichert, Martin Lehnert, Swaantje Casjens, Beate Pesch, Daniel G Weber, Thomas Brüning, Georg Johnen, Thomas Behrens Abstract Background: Asbestos causes mesothelioma and lung cancer. In the European Union, asbestos was banned in 2005, but it is still in use in many other countries.…
Read MoreDiscrimination of Malignant Pleural Mesothelioma Cell Lines Using Amino Acid Metabolomics with HPLC
Biological & Pharmaceutical Bulletin 2022 [Link] Ryoko Tomita, Nao Nishijo, Tadashi Hayama, Toshihiro Fujioka Abstract Malignant pleural mesothelioma (MPM) is a malignancy closely associated with asbestos exposure. Although early diagnosis provides a chance of effective treatment and better prognosis, invasive biopsy and cytological procedure are required for definitive diagnosis. In this study, we developed a…
Read MoreUnexplained Pleural Effusion Leads to the Revelation of a Malignant Mesothelioma: A Case Report
Cureus 2022 April 25 [Link] Meriem Rhazari, Othman Moueqqit, Sara Gartini, Sanae El Morabit, Safae Diani, Mohammed Aharmim, Afaf Thouil, Hatim Kouismi, Jamal Eddine El Bourkadi Abstract Malignant mesothelioma is a rare and aggressive cancer that usually affects subjects with prior asbestos exposure, a major risk factor that has been widely known as carcinogenic, and…
Read MoreMultimodal Treatment of Malignant Pleural Mesothelioma: Real-World Experience with 112 Patients
Cancers 2022 April 30 [Link] Arnulf Holzknecht, Oliver Illini, Maximilian J Hochmair, Dagmar Krenbek, Ulrike Setinek, Florian Huemer, Erwin Bitterlich, Christoph Kaindl, Vladyslav Getman, Ahmet Akan, Michael Weber, Gunther Leobacher, Arschang Valipour, Michael R Mueller, Stefan B Watzka Abstract Malignant pleural mesothelioma (MPM) is a rare pleural cancer associated with asbestos exposure. According to current…
Read MoreSplicing deregulation, microRNA and notch aberrations: fighting the three-headed dog to overcome drug resistance in malignant mesothelioma
Expert Review of Clinical Pharmacology 2022 May 15 [Link] Dario P Anobile, Giulia Montenovo, Camilla Pecoraro, Marika Franczak 1 5, Widad Ait Iddouch, Godefridus J Peters, Chiara Riganti, Elisa Giovannetti Abstract Introduction: Malignant mesothelioma (MMe) is an aggressive rare cancer of the mesothelium, associated with asbestos exposure. MMe is currently an incurable disease at all…
Read MoreDownregulation of FTL decreases proliferation of malignant mesothelioma cells by inducing G 1 cell cycle arrest
Oncology Letters 2022 June [Link] Takahiro Kambara, Vishwa Jeet Amatya, Kei Kushitani, Yutaro Fujii, Ihiro Endo, Yukio Takeshima Abstract Pleural malignant mesothelioma is a malignant tumor with a poor prognosis that is strongly associated with asbestos exposure during its development. Because there is no adequate treatment for malignant mesothelioma, investigation of its molecular mechanism is…
Read MoreAssessment protocol of mesothelioma and relevance of SEM-EDS analysis through a case studies of legal medicine of Brescia (Italy)
Legal Medicine 2022 April 22 [Link] Francesca Maghin, Anna Antonietti, Nicoletta Cerri, Liliana Maria Lancini, Andrea Maccarinelli, Samuele Manzoni, Mario Restori, Matteo Rota, Daniela Ruffini, Andrea Verzeletti, Adelaide Conti Abstract Introduction: This study evaluates the assessment protocol that allows the correlation between the development of mesothelioma to a specific exposure, with particular focus on investigations…
Read MorePulmonary Asbestos Fiber Burden is Related to Patient Survival in Malignant Pleural Mesothelioma
Journal of Thoracic Oncology 2022 March 30 [Link] Sanna Laaksonen, Eeva Kettunen, Eva Sutinen, Ilkka Ilonen, Tapio Vehmas, Timo Törmäkangas, Jari Räsänen, Henrik Wolff, Marjukka Myllärniemi Abstract Introduction: Malignant pleural mesothelioma (MPM) is associated with poor prognosis and is strongly associated with occupational asbestos exposure. Given the importance of asbestos exposure in MPM pathogenesis, we…
Read MoreComparison of 3 Randomized Clinical Trials of Frontline Therapies for Malignant Pleural Mesothelioma
JAMA Network Open 2022 March 1 [Link] Tomer Meirson, Francesca Pentimalli, Francesco Cerza, Giovanni Baglio, Steven G Gray, Pierpaolo Correale, Marija Krstic-Demonacos, Gal Markel, Antonio Giordano, David Bomze, Luciano Mutti Abstract Importance: Some recently proposed frontline therapies for malignant pleural mesothelioma (MPM) are very costly, yet their impact on quality of life and overall survival…
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