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Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Peritoneal (Abdominal Mesothelioma)

Malignant peritoneal mesothelioma; cancer of the lining of the abdominal caviety.

A Phase II Trial of Alisertib (MLN8237) in Salvage Malignant Mesothelioma

The Oncologist 2020 July 1 [Link] Carl M Gay, Yanhong Zhou, J Jack Lee, Xi Ming Tang, Wei Lu, Ignacio I Wistuba, Renata Ferrarotto, Don L Gibbons, Bonnie S Glisson, Merrill S Kies, George R Simon, John V Heymach, Anne S Tsao Abstract Lessons learned: Treatment with the Aurora kinase A inhibitor yields often durable […]

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Genomic Profiling of Multiple Primary Cancers Including Synchronous Lung Adenocarcinoma and Bilateral Malignant Mesotheliomas: Identification of a Novel BAP1 Germline Variant

Pathology International 2020 June 24 [Link] Aya Shinozaki-Ushiku, Shinji Kohsaka, Hidenori Kage, Katsutoshi Oda, Kiyoshi Miyagawa, Jun Nakajima, Hiroyuki Aburatani, Hiroyuki Mano, Tetsuo Ushiku Abstract We report a case with a rare combination of synchronous lung adenocarcinoma and bilateral malignant pleural mesotheliomas in a 70-year-old male without asbestos exposure. He metachronously developed peritoneal malignant mesothelioma, […]

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Cisplatin Plus Pemetrexed Therapy and Subsequent Immune Checkpoint Inhibitor Administration for Malignant Peritoneal Mesothelioma Without Pleural Lesions: Case Report

Medicine 2020 May 29 [Link] Hiroaki Ikushima, Toshio Sakatani, Sayaka Ohara, Hideyuki Takeshima, Hajime Horiuchi, Teppei Morikawa, Kazuhiro Usui Abstract Rationale: Malignant peritoneal mesothelioma is a rare tumor with a poor prognosis and has no recommended therapy after first-line pemetrexed and platinum-based chemotherapy. Moreover, effects of immune checkpoint inhibitors on peritoneal mesothelioma remains to be […]

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Malignant Pleural Mesothelioma: Genetic and Microenviromental Heterogeneity as an Unexpected Reading Frame and Therapeutic Challenge

Cancers 2020 May 7 [Link] David Michael Abbott, Chandra Bortolotto, Silvia Benvenuti, Andrea Lancia, Andrea Riccardo Filippi, Giulia Maria Stella Abstract Mesothelioma is a malignancy of serosal membranes including the peritoneum, pleura, pericardium and the tunica vaginalis of the testes. Malignant mesothelioma (MM) is a rare disease with a global incidence in countries like Italy […]

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Survivin Expression as an Independent Predictor of Overall Survival in Malignant Peritoneal Mesothelioma

Oncology Letters 2020 June [Link] Guozun Zhang, Dong-Liang Yang, Guoqi Zheng, Yufei Liang Abstract Malignant peritoneal mesothelioma (MPeM) is an incurable cancer strongly associated with asbestos exposure and characterised by poor prognosis. The aim of the present study was to elucidate the prognostic and predictive value of CD146 and survivin expression in MPeM. Diagnostic biopsies […]

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Localized Biphasic Malignant Mesothelioma Presenting as a Giant Pelvic Wall Mass: A Rare Case Report and Literature Review

BMC Medical Imaging 2020 May 6 [Link] Yunsong Liu, Jingjun Wu, Ying Zhao, Pengxin Zhang, Zhengyu Hua, Wan Dong, Tao Lin, Ailian Liu Abstract Background: Localized biphasic MPeM is rare in clinical practice, we reviewed 8 cases of localized biphasic MPeM (including our present case), and summarized the clinical and imaging features of the disease. […]

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PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach.

Journal of Cellular and Molecular Medicine 2020 April 17 [Link] Barbarino M, Cesari D, Bottaro M, Luzzi L, Namagerdi A, Bertolino FM, Bellan C, Proietti F, Somma P, Micheli M, de Santi MM, Guazzo R, Mutti L, Pirtoli L, Paladini P, Indovina P, Giordano A Abstract Malignant mesothelioma (MM) is an aggressive asbestos-related cancer of […]

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Malignant mesothelioma following repeated exposures to cosmetic talc: A case series of 75 patients.

American Journal of Industrial Medicine 2020 March 16 [Link] Emory TS, Maddox JC, Kradin RL Abstract BACKGROUND: Asbestos is the primary known cause of malignant mesothelioma. Some cosmetic talc products have been shown to contain asbestos. Recently, repeated exposures to cosmetic talc have been implicated as a cause of mesothelioma. METHODS: Seventy-five individuals (64 females; […]

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Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review.

International Journal of Molecular Science 2020 March 7 [Link] Baldi A, De Luca A, Maiorano P, D’Angelo C, Giordano A Abstract Malignant mesothelioma is an infrequent tumor that initiates from the mesothelial cells lining of body cavities. The great majority of mesotheliomas originate in the pleural cavity, while the remaining cases initiate in the peritoneal […]

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A Mesothelial Inclusion Cyst Presenting in a 40-Year-Old Woman as Abdominal Pain and Bloating – A Rare Diagnosis.

European Journal of Case Reports in Internal Medicine 2020 January 24 [Link] Canadas S, Fernandes R, Almeida H, Correia JS Abstract Cystic mesotheliomas (also called mesothelial inclusion cysts) are rare benign neoplasms that occur more often in young women. Symptoms are usually non-specific, demanding a thorough work-up. We report a case of a 40-year-old female […]

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