Peritoneal (Abdominal Mesothelioma)
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo
Biology Direct 2023 April 17 [Link] Monica Benvenuto, Valentina Angiolini, Chiara Focaccetti, Daniela Nardozi, Camilla Palumbo, Raffaele Carrano, Alessandra Rufini, Riccardo Bei, Martino Tony Miele, Patrizia Mancini, Giovanni Barillari, Mara Cirone, Elisabetta Ferretti, Grazia Raffaella Tundo, Luciano Mutti, Laura Masuelli, Roberto Bei Abstract Background: Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis.…
Read MoreSurgical phenotype of patients with peritoneal mesothelioma and a germline mutation
Cancer 2023 April 12 [Link] Yaniv Berger, Meghana Gadiraju, Ankit Dhiman, Katie Gilliam, Buerkley Opalecky, Heather Chen, Maria Helgeson, Oliver S Eng, Aliya N Husain, Michael W Drazer, Hedy L Kindler, Jane E Churpek, Kiran K Turaga Abstract Background: This study aimed to investigate if peritoneal mesothelioma (PM) patients with germline mutations (GM) have distinct…
Read MoreSurgical case report: The rare case of incidental retroperitoneal mesothelioma
International Journal of Surgery Case Reports 2023 April [Link] Yat Cheung Chung, Travis Ackermann, Yeu Sheng Ang Abstract Introduction and importance: This is a first reported case of isolated retroperitoneal mesothelioma. Most patients present with symptoms of abdominal pain, distension and weight loss. However, a minority of cases are asymptomatic and are found incidentally on…
Read MoreDeveloping sustainable patient and public involvement in mesothelioma research: multi-method exploration with researchers, patients, carers, and patient organisations
Research Involvement and Engagement 2023 March 25 [Link] Afrodita Marcu, Fiona McGregor, Bernadette Egan, Kate Hill, Tim Cook, Anne Arber Abstract Background: Rare diseases where prognosis is poor provide limited scope for patient and public involvement (PPI). One such disease is mesothelioma, a cancer of the lung pleura or of the peritoneum caused by exposure…
Read MoreThe robotic future of minimally invasive cytoreduction and hyperthermic intraperitoneal chemotherapy for peritoneal surface malignancies
Chinese Clinical Oncology 2023 March 13 [Link] Joanna Ortega, Theofano Orfanelli, Edward Levine, Ioannis T Konstantinidis Abstract Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has been increasingly utilized for peritoneal surface malignancies. This has been commonly utilized for a variety of neoplasms, but, especially mucinous neoplasms of the appendix, ovarian cancer, gastric cancer, colorectal cancer…
Read MoreImmunotherapy in malignant peritoneal mesothelioma (Review)
Molecular and Clinical Oncology 2023 February [Link] Sabah Alaklabi, Arya Mariam Roy, Joseph J Skitzki, Renuka Iyer Abstract Over the last decade, there has been a movement in cancer treatment away from cytotoxic therapies toward strategies that enhance the immune system against cancer. Immune checkpoint inhibitors (ICIs) have been incorporated into the treatment regimens for…
Read MoreBenign multicystic peritoneal mesothelioma mimicking mucinous ovarian neoplasm with pseudomyxoma peritonei
BMJ Case Reports 2023 March 7 [Link] Ceylan Altintas Taslicay, Maila Asadullayeva, Aziz Hakki Civriz, Gokhan Posteki Abstract Cystic mesothelioma, also known as benign multicystic peritoneal mesothelioma (BMPM), is a rare neoplasm and one of the five main histological types of peritoneal mesothelioma. Although it is usually considered benign histologically, it is increasingly accepted as…
Read MoreMesothelioma In Situ Mimicking Well-differentiated Papillary Mesothelial Tumor
The American Journal of Surgical Pathology 2023 March 6 [Link] Francoise Galateau-Salle, Trevor Hamilton, Andrea MacNeill, Véronique Hofman, Ruth Sequeiros, Christine Sagan, Nolwenn Le Stang, Andrew Churg Abstract We have previously hypothesized that well-differentiated papillary mesothelial tumor (WDPMT) consists of 2 morphologically identical lesions, one of which is true WDPMT, while the other is a…
Read MoreDefining and targeting tumor-associated macrophages in malignant mesothelioma
Proceedings of the National Academy of Sciences of the United States of America 2023 February 28 [Link] Licun Wu, Mikihiro Kohno, Junichi Murakami, Amin Zia, Jonathan Allen, Hana Yun, Meilin Chan, Cristina Baciu, Mingyao Liu, Veronique Serre-Beinier, Michele De Palma, Emanuela Felley-Bosco, Jonathan Yeung, Trevor J Pugh, Marc de Perrot Abstract Defining the ontogeny of…
Read MoreLong-Term Survival in Patients Treated with Cytoreduction and Heated Intraperitoneal Chemotherapy for Peritoneal Mesothelioma at a Single High-Volume Center
Annals of Surgical Oncology 2023 February 8 [Link] Cristian D Valenzuela, Ian B Solsky, Richard A Erali, Steven D Forsythe, Christopher W Mangieri, Bigyan B Mainali, Gregory Russell, Kathleen C Perry, Konstantinos I Votanopoulos, Perry Shen, Edward A Levine Abstract Background: Malignant peritoneal mesothelioma (MPM) is a rare diagnosis with a dismal prognosis if untreated.…
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