Cureus 2021 September 29 [Link] Aanchal Gupta, Alisa Vasileva, Sukesh Manthri Abstract Malignant mesotheliomas (MM), as described are rare tumors that are mostly associated with occupational exposure to asbestos. They most commonly occur in the pleura. Other unfamiliar sites where they can occur are the peritoneum, pericardium, and tunica vaginalis. There is no significant correlation…

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Annals of Surgical Oncology 2021 October 28 [Link] Vahan Kepenekian, Julien Péron, Benoit You, Isabelle Bonnefoy, Laurent Villeneuve, Mohammad Alyami, Naoual Bakrin, Pascal Rousset, Nazim Benzerdjeb, Olivier Glehen Abstract Background: Diffuse malignant peritoneal mesothelioma (DMPM) is an aggressive primary peritoneal neoplasia. At diagnosis, few patients are eligible for a recommended cytoreductive surgery (CRS) and hyperthermic…

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JTO Clinical and Research Reports 2021 September 17 [Link] Azam Ghafoor, Idrees Mian, Cathy Wagner, Yvonne Mallory, Maria Garcia Agra, Betsy Morrow, Jun S Wei, Javed Khan, Anish Thomas, Manjistha Sengupta, Seth M Steinberg, Raffit Hassan Abstract Introduction: PARP inhibition may enhance antitumor responses in BAP1-associated mesothelioma by inducing synthetic lethality. Methods: A single-center, nonrandomized,…

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BMC Gastroenterology 2021 October 12 [Link] Kelarji Ahmad Beshr, Alshutaihi Mohammad Sami, Ghazal Ahmad, Mahli Nihad, Sarab Agha Abstract Background: Benign Multicystic Peritoneal Mesothelioma (BMPM) is one of the rarest diseases in medicine with only more than 200 cases worldwide. This paper aims to report a case of Benign Multicystic Peritoneal Mesothelioma that strangely arose…

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Biomolecules 2021 August 25 [Link] Danijela Štrbac, Vita Dolžan Abstract Metalloproteinases (MMPs) have an important role in tissue remodeling and have been shown to have an effect on tumor progression, invasion, metastasis formation, and apoptosis in several tumors, including mesothelioma. Mesothelioma is a rare tumor arising from pleura and peritoneum and is frequently associated with…

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Nutrition and Cancer 2021 September 17 [Link] Sabahattin Cömertpay, Abdülmecit Gül, Mehmet Delibaş, Mehmet Semih Tekin Turhan Abstract Mesothelioma is a highly lethal cancer developing in the lung, heart, and abdominal membranes. Zingerone, a capsaicin-like bioactive compound, has been shown to have anticancer properties. Transient Receptor Potential Vanilloid 1 (TRPV1) is an ion channel involving…

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Nutrition and Cancer 2021 September 17 [Link] Sabahattin Cömertpay, Abdülmecit Gül, Mehmet Delibaş, Mehmet Semih Tekin Turhan Abstract Mesothelioma is a highly lethal cancer developing in the lung, heart, and abdominal membranes. Zingerone, a capsaicin-like bioactive compound, has been shown to have anticancer properties. Transient Receptor Potential Vanilloid 1 (TRPV1) is an ion channel involving…

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Abdominal Radiology 2021 August 3 [Link] Isha D Atre, Gaurav V Watane, Mukesh G Harisinghani Abstract Purpose: To identify correlation between CT imaging features and histologic subtypes of Malignant Peritoneal Mesothelioma (MPM). Methods: This was a retrospective single-center study of 51 consecutive patients with the diagnosis of Malignant Peritoneal Mesothelioma (MPM). The tumors were classified…

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The American Journal of Surgical Pathology 2021 August 19 [Link] David B Chapel, Michelle S Hirsch Abstract Primary peritoneal malignant mesothelioma (MM) can demonstrate morphologic overlap with low-grade and high-grade tubo-ovarian serous neoplasms; it is also biologically and prognostically distinct from benign mesothelial proliferations. Currently, there is no single biomarker that can definitively distinguish these…

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Diagnostics 2021 July 16 [Link] Abstract Background: Malignant mesothelioma (MM) is an aggressive and incurable carcinoma that is primarily caused by asbestos exposure. However, the current diagnostic tool for MM is still under-developed. Therefore, the aim of this study is to explore the diagnostic significance of a strategy that combined plasma-based metabolomics with machine learning…

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