Peritoneal (Abdominal Mesothelioma)
BAP1 and Claudin-4, But Not MTAP, Reliably Distinguish Borderline and Low-grade Serous Ovarian Tumors From Peritoneal Mesothelioma
International Journal of Gynecological Pathology 2022 March 29 [Link] Kyle M Devins, Lawrence Zukerberg, Jaclyn C Watkins, Yin Pun Hung, Esther Oliva Abstract Peritoneal mesothelioma (PM) and serous neoplasms can be difficult to differentiate, particularly in small biopsies. BRCA1-associated protein 1 (BAP1) is expressed in benign tissues, but over 50% of PMs demonstrate complete loss…
Read MoreUltra-high drug loading improves nanoparticle efficacy against peritoneal mesothelioma
Biomaterials 2022 April 20 [Link] Robert C Sabatelle, Rong Liu, Yin P Hung, Eric Bressler, Eliza J Neal, Andrew Martin, Iriny Ekladious, Mark W Grinstaff, Yolonda L Colson Abstract Peritoneal mesothelioma is an aggressive disease with a median survival of under three years, due to a lack of effective treatment options. Mesothelioma is traditionally considered…
Read MoreExpression of PD-L1 in Patients With Malignant Peritoneal Mesothelioma: A Pilot Study
The Journal of Surgical Research 2022 April 27 [Link] Victor P Gazivoda, Aaron W Kangas-Dick, Alissa A Greenbaum, Joshua Roshal, Chunxia Chen, Dirk F Moore, Russell C Langan, Timothy J Kennedy, Christine Minerowicz, H Richard Alexander Abstract Introduction: Frequency of PD-L1 expression and the role of immunotherapy in malignant peritoneal mesothelioma (MPM) have not been…
Read MoreNPM2 in malignant peritoneal mesothelioma: from basic tumor biology to clinical medicine
World Journal of Surgical Oncology 2022 April 30 [Link] He-Liang Wu, Zhi-Ran Yang, Li-Jun Yan, Yan-Dong Su, Ru Ma, Yan Li Abstract Background: This review systematically summarizes gene biology features and protein structure of nucleoplasmin2 (NPM2) and the relationship between NPM2 and malignant peritoneal mesothelioma (MPM), in order to explore the molecular pathological mechanism of…
Read MoreA Definitive Prognostication System for Patients With Thoracic Malignancies Diagnosed With Coronavirus Disease 2019: An Update From the TERAVOLT Registry
Journal of Thoracic Oncology 2022 May [Link] Jennifer G Whisenant, Javier Baena, Alessio Cortellini, Li-Ching Huang, Giuseppe Lo Russo, Luca Porcu, Selina K Wong, Christine M Bestvina, Matthew D Hellmann, Elisa Roca, Hira Rizvi, Isabelle Monnet, Amel Boudjemaa, Jacobo Rogado, Giulia Pasello, Natasha B Leighl, Oscar Arrieta, Avinash Aujayeb, Ullas Batra, Ahmed Y Azzam, Mojca…
Read MoreBenign multicystic peritoneal mesothelioma occurring in bilateral inguinal canals metachronously: a case report
Surgical Case Reports 2022 March 16 [Link] Hiroyuki Oshikiri 1 2, Yohei Ozawa 3, On Suzuki 4, Masahiro Usuda 4, Go Miyata Abstract Background: Benign multicystic peritoneal mesothelioma (BMPM) is a benign tumor that usually occurs in middle-aged females. Although several published studies have reported the occurrence of this tumor in the abdominal cavity, few…
Read MoreRepeat Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy for Cancers with Peritoneal Metastasis: A 30-year Institutional Experience
Annals of Surgical Oncology 2022 March 14 [Link] Cristian D Valenzuela, Edward A Levine, Christopher W Mangieri, Rohin Gawdi, Omeed Moaven, Gregory Russell, Megan E Lundy, Kathleen C Perry, Konstantinos I Votanopoulos, Perry Shen Abstract Background: Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) improves survival in abdominal cancer patients with metastatic disease limited to the…
Read MoreBenign Multicystic Peritoneal Mesothelioma Presents as a Tumor in an Elderly Man: An Uncommon Diagnosis
Qatar Medical Journal 2022 February 22 [Link] Ahmet Askar, Ergin Erginoz, Ayse Hanım Yavuz, Vedat Durgun Abstract Background: Mesotheliomas are benign masses that can arise from any body parts that contain mesothelium, such as the abdominal, pelvic, pleural, and pericardial cavities. Benign multicystic peritoneal mesothelioma is a cystic tumor that arises from peritoneal mesothelial cells.…
Read MoreMolecular Pathways in Peritoneal Mesothelioma: A Minireview of New Insights
Frontiers in Oncology 2022 February 10 [Link] Francesco Fortarezza, Federica Pezzuto, Andrea Marzullo, Domenica Cavone, Daniele Egidio Romano, Antonio d’Amati, Gabriella Serio, Luigi Vimercati Abstract Mesothelioma is a rare malignant neoplasm with poor survival. It mainly affects the pleura (90%) but can arise in all serous cavities: peritoneum (5-10%), pericardium and tunica vaginalis testis (<1%).…
Read MoreNovel and Future Treatment Options in Mesothelioma: A Systematic Review
International Journal of Molecular Sciences 2022 February 10 [Link] Danijela Štrbac, Vita Dolžan Abstract Mesothelioma is a rare tumor, frequently associated with asbestos exposure, arising from pleura and peritoneum. Traditionally, diagnosis and treatment have been difficult in a clinical setting. The treatment is based on a trimodal approach involving surgery, chemotherapy, and radiotherapy. The introduction…
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