Tomotherapy in malignant mesothelioma: a planning study to establish dose constraints.

Strahlentherapie and Onkologie 2019 March 26 [Link] Leitzen C, Wilhelm-Buchstab T, Stumpf S, Heimann M, Koch D, Schmeel C, Simon B, Vornholt S, Garbe S, Röhner F2, Schoroth F, Schild HH, Schüller H, Müdder T Abstract PURPOSE: A planning study was performed for helical tomotherapy treatment. We evaluated the maximum achievable protection of organs at risk…

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Optimal gross tumor volume definition in lung-sparing intensity modulated radiotherapy for pleural mesothelioma: an in silico study

Acta Oncologica 2016 October 12 [Epub ahead of print] [Link] Botticella A, Defraene G, Nackaerts K, Deroose CM, Coolen J, Nafteux P, Peeters S, Ricardi U, De Ruysscher D Abstract BACKGROUND: The gross tumor volume (GTV) definition for malignant pleural mesothelioma (MPM) is ill-defined. We therefore investigated which imaging modality is optimal: computed tomography (CT)…

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Circulating epigenetic biomarkers in lung malignancies: From early diagnosis to therapy

Lung Cancer (Amsterdam, Netherlands) 2016 June 2 [Epub ahead of print] [Link] Tomasetti M, Amati M, Neuzil J, Santarelli L Abstract Lung cancer (LC) and malignant mesothelioma (MM) are malignancies linked to environmental/occupational exposure, which are increasing in incidence. Despite advances in chemotherapy, radiation therapy and surgical management of LC and MM, the median survival…

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Malignant pleural mesothelioma: initial experience in integrated 18F-FDG PET/MR imaging

Clinical Imaging 2016 May 11 [Epub ahead of print] [Link] Schaarschmidt BM, Sawicki LM, Gomez B, Grueneisen J, Hoiczyk M, Heusch P, Buchbender C. Asbstract PURPOSE: This study aims to compare staging results of 18F-FDG PET/computed tomography (CT) and integrated PET/magnetic resonance (MR) in malignant pleural mesothelioma (MPM) patients and to investigate a potential apparent…

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Tomotherapy after pleurectomy/decortication or biopsy for malignant pleural mesothelioma allows the delivery of high dose of radiation in patients with intact lung

Journal of Thoracic Oncology. 2012 Dec;7(12):1862-6. doi: 10.1097/JTO.0b013e318272601f. [Link] Minatel E, Trovo M, Polesel J, Rumeileh IA, Baresic T, Bearz A, Del Conte A, Franchin G, Gobitti C, Drigo A, Dassie A, Pagan V, Trovo MG. Departments of Radiation Oncology, Epidemiology and Biostatistics, Nuclear Medicine, and Medical Oncology, Centro di Riferimento Oncologico of Aviano, Italy;…

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