Frontiers in Endocrinology 2022 November 29 [Link] Yingqi Xiao, Wei Huang, Li Zhang, Hongwei Wang Abstract Background: Glycolysis-related genes as prognostic markers in malignant pleural mesothelioma (MPM) is still unclear. We hope to explore the relationship between glycolytic pathway genes and MPM prognosis by constructing prognostic risk models through bioinformatics and machine learning. Methods: The…

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La Medicina del Lavoro 2022 December 7 [Link] Luca Ferrari, Simona Iodice, Laura Cantone, Barbara Dallari, Laura Dioni, Lorenzo Bordini, Alessandro Palleschi, Carolina Mensi, Angela Cecilia Pesatori Abstract Background: Malignant pleural mesothelioma (MPM) is a rare highly aggressive tumor strongly associated with asbestos exposure and characterized by poor prognosis. Currently, diagnosis is based on invasive…

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Journal of Cancer Research and Therapeutics 2022 Oct-Dec [Link] Srushti Karmarkar, Bharat Rekhi, Kedar K Deodhar, Santosh Menon Abstract Background: Malignant peritoneal mesotheliomas (MPMs) are rare tumors with overlapping clinical and histopathological features, especially with epithelial ovarian carcinomas (EOCs). There is no substantial documentation on these rare tumors from our country. Objective: To study the…

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BMJ Open 2022 November 10 [Link] Ruairi J H Conway, Jenny Symonds, Deborah Walton, Janet Probets, Charles Comins, Louise Stadon, John E Harvey, Kevin G Blyth, Nick A Maskell, Anna C Bibby Abstract Introduction: Mesothelioma is a heterogeneous disease that can be challenging to monitor and prognosticate. ASSESS-meso is a multicentre, prospective, longitudinal observational cohort…

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Scientific Reports 2022 November 2 [Link] Takuya Hiratsuka, Takushi Yamamoto, Akihiko Yoshizawa, Shinya Toyokuni, Tatsuaki Tsuruyama Abstract Diagnostic markers of malignant mesothelioma (MM) have been extensively investigated. Immunohistochemistry (IHC) markers, such as calretinin, have been used for pathologic diagnosis. However, more diagnostic markers are required to improve the specificity and sensitivity of pathologic diagnosis. This…

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Frontiers in Oncology 2022 October 11 [Link] Arivazhagan Roshini, Chandra Goparaju, Somanath Kundu, Mohan S Nandhu, Sharon L Longo, John A Longo, Joan Chou, Frank A Middleton, Harvey I Pass, Mariano S Viapiano Abstract Malignant pleural mesothelioma (MPM) is an aggressive tumor with poor prognosis and limited therapeutic options. The extracellular matrix protein fibulin-3/EFEMP1 accumulates…

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International Journal of Cancer 2022 October 28 [Link] Alessandra Allione, Clara Viberti, Ilaria Cotellessa, Chiara Catalano, Elisabetta Casalone, Giovanni Cugliari, Alessia Russo, Simonetta Guarrera, Dario Mirabelli, Carlotta Sacerdote, Marco Gentile, Fabian Eichelmann, Matthias B Schulze, Sophia Harlid, Anne Kirstine Eriksen, Anne Tjønneland, Martin Andersson, Martijn E T Dollé, Heleen Van Puyvelde, Elisabete Weiderpass, Miguel Rodriguez-Barranco,…

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Cancer Medicine 2022 October 19 [Link] Anders Hjerpe, Enes Demir, Sulaf Abd-Own, Katalin Dobra Abstract Background: Pleural mesothelioma (PM) is typically diagnosed late during the disease. Earlier detection can increase the chance of effective therapy. Recurrent pleural effusions are the earliest symptoms displaying an array of cytomorphological changes from reactive atypia to malignancy. Diagnosis is…

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PLoS One 2022 October 14 [Link] Carmina Jiménez-Ramírez, Daniel Gilbert Weber, Guadalupe Aguilar-Madrid, Alexander Brik, Cuauhtémoc Arturo Juárez-Pérez, Swaantje Casjens, Irina Raiko, Thomas Brüning, Georg Johnen, Alejandro Cabello-López Abstract Malignant pleural mesothelioma (MPM) is a cancer associated with asbestos exposure and its diagnosis is challenging due to the moderate sensitivities of the available methods. In…

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International Journal of Radiation Oncology, Biology, Physics 2022 October 3 [Link] Michela Cangemi, Marcella Montico, Marco Trovo, Emilio Minatel, Emanuela Di Gregorio, Giuseppe Corona, Fabiana Giordari, Elisa Comaro, Francesca Colizzi, Lorena Baboçi, Agostino Steffan, Alberto Revelant, Elena Muraro Abstract Purpose: The present study aimed at evaluating the baseline immune profile and the immunomodulating effects of…

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