Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell

International Journal of Biological Sciences 2016 October [Link] Sohn EJ, Won G, Lee J, Yoon SW, Lee I, Kim HJ, Kim SH Abstract Malignant pleural mesothelioma (MPN), which is caused by asbestos exposure, is one of aggressive lung tumors. In the present study, we elucidated the anti-tumor mechanism of ursolic acid in malignant mesotheliomas. Ursolic…

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Mesothelioma in the United States: a Surveillance, Epidemiology, and End Results (SEER)-Medicare investigation of treatment patterns and overall survival

Clinical Epidemiology 2016 October [Link] Beebe-Dimmer JL, Fryzek JP, Yee CL, Dalvi TB, Garabrant DH, Schwartz AG, Gadgeel S Abstract INTRODUCTION: Mesothelioma is a rare malignancy typically associated with exposure to asbestos and poor survival. The purpose of this investigation was to describe mesothelioma patient characteristics, treatment patterns, and overall survival (OS) utilizing the National…

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Simple benchmark for mesothelioma projection for Great Britain

Occupational and Environmental Medicine 2016 May 31 [Epub ahead of print] [Link] Martínez-Miranda MD, Nielsen B, Nielsen JP. Abstract BACKGROUND: It is of considerable interest to forecast the future burden of mesothelioma mortality. Data on deaths are available, whereas no measure of asbestos exposure is available. METHODS: We compare two Poisson models: a response-only model…

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Primary malignant pericardial mesothelioma-a rare cause of superior vena cava thrombosis and constrictive pericarditis

Journal of Thoracic Disease 2014 December [Link] Gong W, Ye X, Shi K, Zhao Q. Abstract Primary malignant pericardial mesothelioma (PMPM) is an extremely rare, highly lethal and often misdiagnosed tumor. We report a 60-year-old woman complaining of dry cough, shortness of breath and exertional dyspnea due to a large pericardial effusion. The pericardial fluid…

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Incidence and Survival of Malignant Pleural Mesothelioma in Norway: A Population-Based Study of 1686 Cases

Journal of Thoracic Oncology. 2012 Dec;7(12):1858-61. doi: 10.1097/JTO.0b013e318275b346. [Link] Helland A, Solberg S, Brustugun OT. Department of Oncology, Oslo University Hospital-The Norwegian Radium Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway; and Department of Thoracic Surgery, Oslo University Hospital-Rikshospitalet, Oslo, Norway. Abstract Background: Asbestos-related malignant pleural mesothelioma is one of the…

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Occupational Respiratory Cancer in Korea

Journal of Korean Medical Science. 2010 Dec;25(Suppl):S94-S98. Epub 2010 Dec 15. [Link] Lee HE, Kim HR. Occupational Safety and Health Research Institute, KOSHA, Inchoen, Korea. Abstract Malignant mesothelioma and lung cancer are representative examples of occupational cancer. Lung cancer is the leading cause of cancer death, and the incidence of malignant mesothelioma is expected to…

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Asbestos-related occupational lung diseases in NSW, Australia and potential exposure of the general population

Industrial Health. 2008 Dec;46(6):535-40. [Link] Park EK, Hannaford-Turner KM, Hyland RA, Johnson AR, Yates DH. Research and Education Unit, Workers’ Compensation Dust Diseases Board of NSW, Sydney, Australia. Abstract Asbestos is a fibrous silicate which is recognized as causing a variety of lung disorders including malignant mesothelioma of the pleura, lung cancer and asbestosis. Asbestos…

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Mesothelioma in the Republic of Kazakhstan: a review

Gigiena i Sanitariia. 2008 Sep-Oct;(5):13-7. [Article in Russian] [Link] Kashanskii SV, Zhetpisbaev BA, Il’derbaev OZ, Ermenbai OT. Abstract The paper presents the results of a review of 69 reports published by Kazakhstan scientists over 50 years. For this period, mesotheliomas were diagnosed in 5 of 14 areas of the country. The basic clinical, demographic, medical,…

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Recent mortality from pleural mesothelioma, historical patterns of asbestos use, and adoption of bans: a global assessment

Environmental Health Perspectives. 2008 Dec;116(12):1675-80. Epub 2008 Aug 14. [Link] Nishikawa K, Takahashi K, Karjalainen A, Wen CP, Furuya S, Hoshuyama T, Todoroki M, Kiyomoto Y, Wilson D, Higashi T, Ohtaki M, Pan G, Wagner G. Department of Environmental Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu City, Japan. Abstract…

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Etiology, epidemiology, biology. Occupational respiratory cancers

Revue des Maladies Respiratoires. 2008 Oct;25(8 Pt 2):3S18-31. [Link] Pairon JC, Andujar P, Matrat M, Ameille J. INSERM Unité 841, Créteil, France. JC.Pairon@chicreteil.fr Abstract Lung cancer and pleural mesothelioma are the most common occupational cancers. Recent epidemiological studies have estimated that the fraction attributable to occupational factors varies from 13 to 29% for lung cancer…

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