Journal of Medical Internet Research 2020 November 12 [Link] Roma Maguire, John Connaghan, Anne Arber, Naomi Klepacz, Kevin G Blyth, John McPhelim, Paul Murray, Hitasha Rupani, Anoop Chauhan, Peter Williams, Laura McNaughton, Kirstie Woods, Anne Moylan Abstract Background: Patients with malignant pleural mesothelioma (MPM) have a life-limiting illness and short prognosis and experience many debilitating…

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EBioMedicine 2020 November 6 [Link] Joanne M Mankor, Maria J Disselhorst, Myrthe Poncin, Paul Baas, Joachim G J V Aerts, Heleen Vroman Abstract Background: Combined immune checkpoint inhibitor (ICI) treatment targeting PD-1 and CTLA-4 was suggested to yield clinical benefit over chemotherapy in malignant pleural mesothelioma (MPM), whereas aPD-1 monotherapy failed to provide benefit in…

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Lung Cancer 2020 October 20 [Link] Sarah J Danson, Joe Conner, John G Edwards, Kevin G Blyth, Patricia M Fisher, Munitta Muthana, Abdulazeez Salawu, Fiona Taylor, Elizabeth Hodgkinson, Patrick Joyce, Jennifer Roman, Kathleen Simpson, Alexander Graham, Kirsty Learmonth, Penella J Woll Abstract Objectives: Malignant Pleural Mesothelioma (MPM) remains a major oncological challenge with limited therapeutic…

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Journal of Pathology and Translational Medicine 2020 November 9 [Link] Hanife Gulnihal Ozdemir, Sermin Coban Kokten, Nagehan Ozdemir Barisik Abstract Background: Malignant mesothelioma is a highly aggressive tumor that can be confused with a benign mesothelial lesion, especially cytomorphologic lesions. BRCA1-associated protein 1 (BAP1) acts as a tumor suppressor. In this study, we aim to…

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BMC Medical Imaging 2020 November [Link] Hualong Yu, Chuanyu Zhang, Shihe Liu, Gang Jiang, Shaoke Li, Liang Zhang, Yongjie Wang, Wenjian Xu Abstract Background: To investigate the clinical value of CT-guided percutaneous fine-needle aspiration biopsy for peritoneal lesions of unknown nature. Methods: A retrospective analysis was conducted of 84 patients with peritoneal thickening for unknown…

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Frontiers in Endocrinology 2020 October 8 [Link] Iacopo Gesmundo, Francesca Silvagno, Dana Banfi, Valentina Monica, Alessandro Fanciulli, Giacomo Gamba, Noemi Congiusta, Roberta Libener, Chiara Riganti, Ezio Ghigo, Riccarda Granata Abstract Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor, often associated with exposure to asbestos and characterized by poor prognosis and limited treatment options.…

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Respirology Case Reports 2020 October 26 [Link] Mia MacMillan, Bapti Roy, Sally McLaren, Anna K Nowak, Rajesh Thomas, Y C Gary Lee Abstract We report a rare case of early and extensive pulmonary invasion of malignant pleural mesothelioma (MPM) in a 70-year-old woman. She first presented with a hydropneumothorax and subsequent workup, including video-assisted thoracoscopy…

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Scientific Reports 2020 October 29 [Link] Sabrina Borchert, Pia-Maria Suckrau, Robert F H Walter, Michael Wessolly, Elena Mairinger, Julia Steinborn, Balazs Hegedus, Thomas Hager, Thomas Herold, Wilfried E E Eberhardt, Jeremias Wohlschlaeger, Clemens Aigner, Agnes Bankfalvi, Kurt Werner Schmid, Fabian D Mairinger Abstract Malignant pleural mesothelioma (MPM) is a rare, but aggressive tumor with dismal…

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British Journal of Cancer 2020 October 26 [Link] Michael G White, Jefree J Schulte, Lai Xue, Yaniv Berger, Darryl Schuitevoerder, Charles C Vining, Hedy L Kindler, Aliya Husain, Kiran K Turaga, Oliver S Eng Abstract Programmed death-ligand 1 (PD-L1) expression has been described in patients with malignant peritoneal mesothelioma (MPM), but treatment strategies utilising immune…

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Annals of Surgical Oncology 2020 October [Link] Akifumi Nakamura, Nobuyuki Kondo, Toru Nakamichi, Masaki Hashimoto, Teruhisa Takuwa, Seiji Matsumoto, Kozo Kuribayashi, Takashi Kijima, Seiki Hasegawa Abstract Background: A few studies have reported the incidence and clinical implications of complications after pleurectomy/decortication (P/D). Objective: The aim of this study was to assess the details of complications…

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