Type of Mesothelioma:
Evaluation of Nonresponse Bias in a Case-Control Study of Pleural Mesothelioma
International Journal of Environmental Research and Public Health 2020 August 24 [Link] Chiara Airoldi, Daniela Ferrante, Dario Mirabelli, Danila Azzolina, Corrado Magnani Abstract Nonparticipation limits the power of epidemiological studies, and can cause bias. In a case-control study on pleural malignant mesothelioma (MM), we found low participation in interviews (63%) among controls. Our goal was…
Read MoreIdentification of a Five-Gene Signature for Predicting Survival in Malignant Pleural Mesothelioma Patients
Frontiers in Genetics 2020 August 7 [Link] Yiyang Bai, Xiao Wang, Jia Hou, Luying Geng, Xuan Liang, Zhiping Ruan, Hui Guo, Kejun Nan, Lili Jiang Abstract Malignant pleural mesothelioma (MPM), predominantly caused by asbestos exposure, is a highly aggressive cancer with poor prognosis. The staging systems currently used in clinics is inadequate in evaluating the…
Read MoreIdentification of a Five-Gene Signature for Predicting Survival in Malignant Pleural Mesothelioma Patients
Frontiers in Genetics 2020 August 7 [Link] Yiyang Bai, Xiao Wang, Jia Hou, Luying Geng, Xuan Liang, Zhiping Ruan, Hui Guo, Kejun Nan, Lili Jiang Abstract Malignant pleural mesothelioma (MPM), predominantly caused by asbestos exposure, is a highly aggressive cancer with poor prognosis. The staging systems currently used in clinics is inadequate in evaluating the…
Read MoreSystematic Analysis of Aberrant Biochemical Networks and Potential Drug Vulnerabilities Induced by Tumor Suppressor Loss in Malignant Pleural Mesothelioma
Cancers 2020 August 17 [Link] Haitang Yang, Duo Xu, Zhang Yang, Feng Yao, Heng Zhao, Ralph A Schmid, Ren-Wang Peng Abstract Background: Malignant pleural mesothelioma (MPM) is driven by the inactivation of tumor suppressor genes (TSGs). An unmet need in the field is the translation of the genomic landscape into effective TSG-specific therapies. Methods: We…
Read MoreEvolution of Genomic and T-cell Repertoire Heterogeneity of Malignant Pleural Mesothelioma Under Dasatinib Treatment
Clinical Cancer Research 2020 August 14 [Link] Runzhe Chen, Won-Chul Lee, Junya Fujimoto, Jun Li, Xin Hu, Reza Mehran, David Rice, Stephen G Swisher, Boris Sepesi, Hai T Tran, Chi-Wan Chow, Latasha D Little, Curtis Gumbs, Cara Haymaker, John V Heymach, Ignacio I Wistuba, J Jack Lee, P Andrew Futreal, Jianhua Zhang, Alexandre Reuben, Anne…
Read MoreInitial clinical experience treating patients with palliative radiotherapy for malignant pleural mesothelioma on the HalcyonTM linear accelerator
Annals of Palliative Medicine 2020 August 14 [Link] Andrew R Barsky, Michele M Kim, Russell Maxwell, Amberly Mendes, Christopher M Wright, Emily J Anstadt, Sally McNulty, Lei Dong, James M Metz, Steven J Feigenberg, Taoran Li, Keith A Cengel Abstract Background: Radiation therapy (RT) can provide effective symptomatic palliation in patients with malignant pleural mesothelioma…
Read MoreSymptom Burden and Unmet Needs in MPM: Exploratory Analyses From the RESPECT-Meso Study
Journal of Palliative Care 2020 August 14 [Link] Siao Nge Hoon, Iain Lawrie, Cathy Qi, Najib Rahman, Nick Maskell, Karen Forbes, Stephen Gerry, Leanne Monterosso, Anoop Chauhan, Fraser J H Brims Abstract Objective: Malignant Pleural Mesothelioma (MPM) has a poor prognosis and high symptom burden. RESPECT-Meso was a multicenter randomized study examining the role of…
Read MoreAdvances with pharmacotherapy for peritoneal metastasis
Expert Opinion on Pharmacotherapy 2020 August 12 [Link] Yutaka Yonemura, Haruaki Iahibashi, Shouzou Sako, Akiyoshi Mizumoto, Nobuyuki Takao, Masumi Ichinose, Shunsuke Motoi, Yang Liu, Satoshi Wakama, Yasuyuki Kamada, Kazurou Nishihara Abstract Introduction: A new treatment strategy involving cytoreductive surgery (CRS) combined with perioperative intraperitoneal (IP) chemotherapy was proposed in 1999 by the Peritoneal Surface Oncology…
Read MoreUsing creative co-design to develop a decision support tool for people with malignant pleural effusion
BMC Medical Informatics and Decision Making 2020 August 5 [Link] Cheryl Grindell, Angela Tod, Remi Bec, Daniel Wolstenholme, Rahul Bhatnagar, Parthipan Sivakumar, Anna Morley, Jayne Holme, Judith Lyons, Maryam Ahmed, Susan Jackson, Deirdre Wallace, Farinaz Noorzad, Meera Kamalanathan, Liju Ahmed, Mathew Evison Abstract Background: Malignant pleural effusion (MPE) is a common, serious problem predominantly seen…
Read MoreTrabectedin in Malignant Pleural Mesothelioma: Results From the Multicentre, Single Arm, Phase II ATREUS Study
Clinical Lung Cancer 2020 July 3 [Link] Diego Cortinovis, Federica Grosso, Luciano Carlucci, Paolo Andrea Zucali, Giulia Pasello, Marcello Tiseo, Francesca Sperandi, Lital Hollander, Francesca Galli, Valter Torri, Eliana Rulli, Stefania Canova, Antonio Maconi, Paolo Bidoli, Giovanni Luca Ceresoli , Maurizio D’Incalci, ATREUS investigators Abstract Introduction: New therapeutic approaches in unresectable malignant pleural mesothelioma (MPM)…
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