March 30, 2020
Biphasic or Mixed, Causation, Epithelioid, Full Archive, Pericardial, Peritoneal (Abdominal Mesothelioma), Pleural, Sarcomatoid, Tunica Vaginalis Testis
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Comparative analysis of prognostic histopathologic parameters in subtypes of epithelioid pleural mesothelioma.
Patients with tubulopapillary or microcystic tumors showed a greater improvement in overall survival after receiving multimodal therapy than those with solid or trabecular tumors. CONCLUSIONS: Histologic subtypes of epithelioid MPM have a prognostic impact and might help to select patients for intensive multimodal treatment approaches.March 27, 2020
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Comprehensive molecular and pathological evaluation of transitional mesothelioma assisted by deep learning approach: a multi institutional study of the International Mesothelioma Panel from MESOPATH Reference Center.
RNA sequencing unsupervised clustering analysis showed that TM grouped together and were closer to SM than to EM. Deep learning analysis achieved a 94% accuracy for TM identification CONCLUSION: These results demonstrated that TM pattern should be classified in non-epithelioid mesothelioma at minimum as a subgroup of SM type.March 26, 2020
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Curcumin as an Anticancer Agent in Malignant Mesothelioma: A Review.
The aim of this review article was to describe recent findings about the anti-cancer activity of curcumin and some of its derivatives on mesotheliomas. The potential clinical implications of these findings are discussed.March 25, 2020
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Immunotherapy in Malignant Pleural Mesothelioma.
Results of combination checkpoint inhibitors with chemotherapy are awaiting.March 24, 2020
Biomarkers, Chemotherapy, Cisplatin (Platinol ®), Full Archive, Immune-based Therapies, Pemetrexed (Alimta), Pleural
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How I treat malignant pleural mesothelioma.
Refer to specialised centres with multidisciplinary expertise is mandatory, as well as inclusion of patients in clinical trials is advisable whenever possible. In all stages of disease focus on symptoms control is paramount.March 23, 2020
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What is Mesothelioma?
Learn more about this fatal cancer, including the causes, symptoms, and treatments for both pleural and peritoneal tumors of the mesothelium at our parent site MesotheliomaCenter.
ADAR2 Regulates Malignant Behaviour of Mesothelioma Cells Independent of RNA-editing Activity.
However, overexpression of ADAR2 that had no enzyme activity did not alter the malignant properties of MPM cells. CONCLUSION: Enhancement of the malignant characteristics of cultured MPM cells via ADAR2 was independent of RNA-editing activity.March 20, 2020
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A Mesothelial Inclusion Cyst Presenting in a 40-Year-Old Woman as Abdominal Pain and Bloating – A Rare Diagnosis.
Investigation unmasks large abdominal lesions. A timely diagnosis is of the utmost importance, to prevent a dramatic change in outcome if severe complications develop.March 19, 2020
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Histopathological features of epithelioid malignant pleural mesotheliomas in patients with extended survival.
024) were associated with prolonged survival. These results may aid in estimating DMM prognosis.March 18, 2020
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Photodynamic Therapy-Based Dendritic Cell Vaccination Suited to Treat Peritoneal Mesothelioma.
DCs pulsed with PDT-killed mesothelioma cells also exhibited a significant increase in CCR7 receptors, together with an intrinsic capacity to migrate towards the lymph nodes. Altogether, these results indicate that PDT-based DC vaccination is particularly suited to induce a potent immune response against peritoneal mesothelioma.March 17, 2020
Full Archive, Immune-based Therapies, Immunohistochemistry or IHC, Peritoneal (Abdominal Mesothelioma), Photodynamic Therapy (PDT)
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