Environmental Asbestos Exposure
Small RNA-Seq Transcriptome Profiling of Mesothelial and Mesothelioma Cell Lines Revealed microRNA Dysregulation after Exposure to Asbestos-like Fibers
Biomedicines 2023 February 13 [Link] Veronica Filetti, Claudia Lombardo, Carla Loreto, George Dounias, Massimo Bracci, Serena Matera, Lucia Rapisarda, Venerando Rapisarda, Caterina Ledda, Ermanno Vitale Abstract Environmental exposure to fibers of respirable size has been identified as a risk for public health. Experimental evidence has revealed that a variety of fibers, including fluoro-edenite, can develop…
Read MoreJourney to the centre of the lung. The perspective of a mineralogist on the carcinogenic effects of mineral fibres in the lungs
Journal of Hazardous Materials 2023 January 15 [Link] Alessandro F Gualtieri Abstract This work reviews the bio-chemical mechanisms leading to adverse effects produced when mineral fibres are inhaled and transported in the lungs from the perspective of a mineralogist. The behaviour of three known carcinogenic mineral fibres (crocidolite, chrysotile, and fibrous-asbestiform erionite) during their journey…
Read MoreEnvironmental asbestos exposure and clustering of malignant mesothelioma in community: a spatial analysis in a population-based case-control study
Environmental Health 2021 September 15 [Link] C Airoldi, C Magnani, F Lazzarato, D Mirabelli, S Tunesi, D Ferrante Abstract Background: Neighborhood exposure to asbestos increases the risk of developing malignant mesothelioma (MM) in residents who live near asbestos mines and asbestos product plants. The area of Casale Monferrato (Northwest Italy) was impacted by several sources…
Read MoreUse of preclinical models for malignant pleural mesothelioma
Thorax 2021 March 10 [Link] Marie Shamseddin, Joanna Obacz, Mathew J Garnett, Robert Campbell Rintoul, Hayley Elizabeth Francies, Stefan John Marciniak Abstract Malignant pleural mesothelioma (MPM) is an aggressive cancer most commonly caused by prior exposure to asbestos. Median survival is 12-18 months, since surgery is ineffective and chemotherapy offers minimal benefit. Preclinical models that…
Read MoreMicroRNAs diagnostic and prognostic value as predictive markers for malignant mesothelioma.
Archives of Environmental and Occupational Health 2020 April 20 [Link] Sturchio E, Berardinelli MG, Boccia P, Zanellato M, Gioiosa S Abstract Malignant mesothelioma is an aggressive tumor resistant to current therapies with a latency period ranging between 20 and 60 years, caused by inhalation of asbestos fibers, that continues to represent a social and healthcare…
Read MoreAsbestos Air Pollution: Description of a Mesothelioma Cluster Due to Residential Exposure from an Asbestos Cement Factory.
International Journal of Environmental Research and Public Health 2020 April 12 [Link] Vimercati L, Cavone D, Delfino MC, Caputi A, De Maria L, Sponselli S, Corrado V, Ferri GM, Serio G Abstract The study describes a cluster of 71 malignant mesothelioma cases among Bari residents without asbestos exposure other than residential exposure. This small cohort,…
Read MoreAssociation between asbestos exposure and pericardial and tunica vaginalis testis malignant mesothelioma: a case-control study and epidemiological remarks.
Scandinavian Journal of Work and Environmental Health 2020 April 7 [Link] Marinaccio A, Consonni D, Mensi C, Mirabelli D, Migliore E, Magnani C, Di Marzio D, Gennaro V, Mazzoleni G, Girardi P, Negro C, Romanelli A, Chellini E, Grappasonni I, Madeo G, Romeo E, Ascoli V, Carrozza F, Angelillo IF, Cavone D, Tumino R, Melis…
Read MoreMeasurement of asbestos emissions associated with demolition of abandoned residential dwellings.
The Science of the Total Environment 2020 March 21 [Link] Neitzel RL, Sayler SK, Demond AH, d’Arcy H, Garabrant DH, Franzblau A Abstract Many cities are revitalizing their urban cores through the demolition of abandoned residential dwellings (ARDs). However, data regarding the emissions of asbestos during such an operation are sparse. We measured airborne asbestos…
Read MoreLung Asbestos Fibre Burden and Pleural Mesothelioma in Women with Non-occupational Exposure.
Annals of Work Exposure and Health 2020 February 17 [Link] Barbieri PG, Somigliana A, Chen Y, Consonni D, Vignola R, Finotto L Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) due to environmental and familial (domestic) asbestos exposure is well recognized. However, information on cumulative asbestos dose in subjects affected by MPM is limited. OBJECTIVES: To evaluate…
Read MoreFollow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study.
Journal of Occupational and Environmental Medicine 2019 November 8 [Link] Larson TC, Williamson L, Antao VC Abstract OBJECTIVE: To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease. METHODS: We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational…
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