Extrapleural Pneumonectomy (EPP)
A randomised phase II study of extended pleurectomy/decortication (e-PD) preceded or followed by chemotherapy in patients (pts) with early-stage pleural mesothelioma (PM): EORTC 1205
The European Respiratory Journal 2024 June 26 [Link] Jo Raskin, Veerle Surmont, Alexander P W M Maat, Maha Yahia, Sjaak A Burgers, Yassin Pretzenbacher, Frederic De Ryck, Robin Cornelissen, Houke M Klomp, Ana Oliveira, Joachim Aerts, Paul Baas, Sandrine Marreaud, Jan P Van Meerbeeck, Paul E Y Van Schil Abstract Background: The role of surgery…
Read MoreSarcomatoid malignant pleural mesothelioma: a case of long-term recurrence-free survival following curative intent surgery alone
Surgical Case Reports 2024 May 31 [Link] Masatoshi Kanayama, Masaru Takenaka, Katsuma Yoshimatsu, Hiroki Matsumiya, Masataka Mori, Koji Kuroda3, Aya Nawata, Manabu Yasuda, Fumihiro Tanaka Abstract Background: Curative intent surgery may be indicated for some patients with resectable early stage malignant pleural mesothelioma (MPM). However, sarcomatoid MPM is a highly aggressive subtype for which curative…
Read MorePredictive potential of MRI in differentiating the predominant component in biphasic pleural mesothelioma
European Journal of Radiology 2024 May 26 [Link] Ritu R Gill, William G Richards, Hillary Heiling, Emanuele Mazzola, Yin P Hung, Ravi T Seethamraju, Lucian R Chirieac, Raphael Bueno Abstract Purpose: To assess the potential of apparent diffusion coefficient (ADC) values derived from diffusion weighted (DW) MRI preoperatively to predict the predominant histologic component among…
Read MoreRisk factors influencing postoperative pleural empyema in patients with pleural mesothelioma: a retrospective single-centre analysis
European Journal of Cardiothoracic Surgery 2024 March 29 [Link] Peter Henschke, Laura Chiara Guglielmetti, Sven Hillinger, Gian-Marco Monsch, Didier Schneiter, Isabelle Opitz, Olivia Lauk Abstract Objectives: Postoperative empyema is a severe, potentially lethal complication also present, but poorly studied in patients undergoing surgery for pleural mesothelioma. We aimed to analyse which perioperative characteristics might be…
Read MoreSafety and efficacy of helical tomotherapy following lung-sparing surgery in locally advanced malignant pleural mesothelioma
Strahlentherapie Und Onkologie 2023 November 22 [Link] Julian P Layer, Pascal Fischer, Cas S Dejonckheere, Gustavo R Sarria, Rebekka Mispelbaum, Sandra Tessa Hattenhauer, Shari Wiegreffe, Andrea R Glasmacher, Katharina Layer, Youness Nour, Lara Caglayan, Franziska Grau, Thomas Müdder 4, Mümtaz Köksal, Davide Scafa, Frank A Giordano, Alberto Lopez-Pastorini, Erich Stoelben, Leonard Christopher Schmeel, Christina Leitzen…
Read MoreLong-Term Survival Analysis of Pleural Mesothelioma Patients Undergoing Surgery: Brief Report From a Tertiary Referral Centre
Clinical Lung Cancer 2023 October 24 [Link] Riccardo Orlandi, Giovanni Leuzzi, Luigi Rolli, Michele Ferrari, Alessia Stanzi, Camilla Valsecchi, Ugo Pastorino Abstract Objectives: to date, no consensus has been reached on the surgical gold-standard in pleural mesothelioma (PM). We retrospectively reviewed our experience as a tertiary referral centre, to compare short- and long-term survival of…
Read MorePleurectomy and decortication are associated with better survival for bicavitary cytoreductive surgery for mesothelioma compared with extrapleural pneumonectomy
Journal of Thoracic and Cardiovascular Surgery 2022 December 14 [Link] R Taylor Ripley, Hudson M Holmes, Richard S Whitlock 2, Shawn S Groth, Cristian G Medina, Eugene A Choi, Bryan M Burt, Paul H Sugarbaker Abstract Objectives: Mesothelioma is a nearly uniformly fatal tumor. Multimodality therapy including cytoreductive surgery and chemotherapy is associated with long-term…
Read MoreMultimodal therapy of epithelioid pleural mesothelioma: improved survival by changing the surgical treatment approach
Translational Lung Cancer Research 2022 November [Link] Laura V Klotz, Hans Hoffmann, Rajiv Shah, Florian Eichhorn, Christiane Gruenewald, Elena L Bulut, Raffaella Griffo, Thomas Muley, Petros Christopoulos, Philip Baum, Peter Huber, Seyer Safi, Marc Kriegsmann, Michael Thomas, Helge Bischoff, Hauke Winter, Martin E Eichhorn Abstract Background: The exact role and type of surgery for malignant…
Read MoreMultifactorial Evaluation following Cytoreductive Surgery for Malignant Pleural Mesothelioma in Patients with High Symptom-Burden
Journal of Clinical Medicine 2022 October 29 [Link] Riccardo Tajè, Roberto Fiorito, Alexandro Patirelis, Valentina Marziali, Vincenzo Ambrogi Abstract Mesothelioma has a scant prognosis and a great impact on symptoms and the quality of life. Pleurectomy/decortication and extrapleural pneumonectomy are the two cytoreductive surgical strategies, with different invasiveness, but achieving similar oncological results. Hereafter, the…
Read MoreImpact of Pleural Thickness on Occurrence of Postoperative Complications in Patients with Malignant Pleural Mesothelioma
Annals of Surgical Oncology 2022 November 13 [Link] Toshinari Ito, Shota Nakamura, Yuka Kadomatsu, Harushi Ueno, Taketo Kato, Naoki Ozeki, Koichi Fukumoto, Toyofumi Fengshi Chen-Yoshikawa Abstract Objectives: The rates of postoperative mortality and morbidity are high in patients with malignant pleural mesothelioma (MPM). Therefore, it is important to identify variables that increase the risk of…
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