Trends Cancer 2020 May 20 [Link] Aishwarya Kulkarni, Matthew T Chang, Joseph H A Vissers, Anwesha Dey, Kieran F Harvey Abstract The Hippo pathway regulates myriad biological processes in diverse species and is a key cancer signaling network in humans. Although Hippo has been linked to multiple aspects of cancer, its role in this disease […]
June 5, 2020
European Journal of Cardiothoracic Surgery 2020 May 25 [Link] Isabelle Opitz, Arnaud Scherpereel, Thierry Berghmans, Ioannis Psallidas, Markus Glatzer, David Rigau, Philippe Astoul, Servet Bölükbas, Jeanette Boyd, Johan Coolen, Charlotte De Bondt, Dirk De Ruysscher, Valerie Durieux, Corinne Faivre-Finn, Dean A Fennell, Francoise Galateau-Salle, Laurent Greillier, Mir Ali Hoda, Walter Klepetko, Aude Lacourt, Phil McElnay, […]
June 4, 2020
International Journal of Biological Macromolecules 2020 May 20 [Link] Snehal K Shukla, Amanda Chan, Vineela Parvathaneni, Vivek Gupta Abstract The purpose of this study was to design and evaluate chitosan dispersed lipid vesicles (chitosomes) as potential delivery carriers for repurposing metformin (Met) against malignant pleural mesothelioma. Chitosomes were prepared by directly hydrating the thin lipid […]
June 3, 2020
Cancers 2020 May 19 [Link] Natalia Trempolec, Charline Degavre, Bastien Doix, Davide Brusa, Cyril Corbet, Olivier Feron Abstract For poorly immunogenic tumors such as mesothelioma there is an imperious need to understand why antigen-presenting cells such as dendritic cells (DCs) are not prone to supporting the anticancer T cell response. The tumor microenvironment (TME) is […]
June 2, 2020
Diagnostic Cytopathology 2020 May 22 [Link] Kenzo Hiroshima, Di Wu, Shinji Hamakawa, Shingo Tsuruoka, Daisuke Ozaki, Hideki Orikasa, Mizue Hasegawa, Eitetsu Koh, Yasuo Sekine, Yoko Yonemori, Kazuki Nabeshima, Shoutaro Tsuji, Yohei Miyagi, Kohzoh Imai Abstract Background: The specificity and sensitivity of HEG1 for malignant mesothelioma (MM) is high. The use of BAP1/MTAP immunohistochemistry (IHC) is […]
June 1, 2020
Thoracic Cancer 2020 May 21 [Link] Hossein Taghizadeh, Sabine Zöchbauer-Müller, Robert M Mader, Leonhard Müllauer, Thomas Klikovits, Thomas Bachleitner-Hofmann, Mir A Hoda, Gerald W Prager Abstract Background: Malignant mesothelioma is an aggressive cancer and has a poor prognosis. Here, we analyzed the feasibility, molecular and gender aspects of targeted therapy recommendations for malignant mesothelioma based […]
May 29, 2020
Archives of Pathology and Laboratory Medicine 2020 February [Link] Fatemeh Derakhshan, Diana Ionescu, Simon Cheung, Andrew Churg Abstract Context.—: The separation of benign from malignant mesothelial proliferations is a difficult morphologic problem. Some mesotheliomas stain for programmed death ligand-1 (PD-L1). Objective.—: To determine whether PD-L1 staining can separate mesotheliomas from reactive mesothelial proliferations (RMPs). Design.—: […]
May 28, 2020
Cancers 2020 May 7 [Link] David Michael Abbott, Chandra Bortolotto, Silvia Benvenuti, Andrea Lancia, Andrea Riccardo Filippi, Giulia Maria Stella Abstract Mesothelioma is a malignancy of serosal membranes including the peritoneum, pleura, pericardium and the tunica vaginalis of the testes. Malignant mesothelioma (MM) is a rare disease with a global incidence in countries like Italy […]
May 27, 2020
Oncology Letters 2020 June [Link] Guozun Zhang, Dong-Liang Yang, Guoqi Zheng, Yufei Liang Abstract Malignant peritoneal mesothelioma (MPeM) is an incurable cancer strongly associated with asbestos exposure and characterised by poor prognosis. The aim of the present study was to elucidate the prognostic and predictive value of CD146 and survivin expression in MPeM. Diagnostic biopsies […]
May 22, 2020
BMC Medical Imaging 2020 May 6 [Link] Yunsong Liu, Jingjun Wu, Ying Zhao, Pengxin Zhang, Zhengyu Hua, Wan Dong, Tao Lin, Ailian Liu Abstract Background: Localized biphasic MPeM is rare in clinical practice, we reviewed 8 cases of localized biphasic MPeM (including our present case), and summarized the clinical and imaging features of the disease. […]
May 21, 2020