BAP-1 in the diagnosis of malignant pleural mesothelioma

Respiratory Medicine and Research 2025 November 28 [Link] Irene Sansano, Ana Vázquez, Oscar Persiva, Marc Simó, Leire Sánchez, Pilar Montoya, Carme Dinarès, Carmen Alemán Abstract Background: The diagnosis of malignant pleural mesothelioma (MPM) can be challenging for clinicians and pathologists. Patients and methods: This study included all patients diagnosed with pleural mesothelioma between October 2013…

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Disaster on MARS2? Lessons Learned from Modern Day Outcomes of Surgery for Pleural Mesothelioma

The Annals of Thoracic Surgery 2026 February 2 [Link] Shubham Gulati, Andrea Wolf, Jai Mehrotra-Varma, Stephanie Tuminello, Emanuela Taioli, Raja Flores Abstract Background: The Mesothelioma and Radical Surgery 2 (MARS2) trial has drawn into question pleurectomy/decortication (PD) for the treatment of pleural mesothelioma. This trial’s evaluation of resectability (poor positron emission tomography/computed tomography utilization, patients…

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Artificial Intelligence in Pleural Diseases: Current Applications and Next Steps

Thoracic Research and Practice 2026 January 30 [Link] Ferhan Karataş, Öner Dikensoy Abstract Pleural diseases pose a significant burden on healthcare systems due to diagnostic challenges and high costs. Artificial intelligence (AI) has the potential to provide faster, more accurate, and more reliable results in the diagnosis of these diseases. This review evaluates the current…

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Multi-omic screening for pleural mesothelioma in Asbestos-Exposed Populations: A literature review and Recommendations

Lung Cancer 2026 February [Link] Kathleen Zwijsen, Ellen Heirwegh, Eline Schillebeeckx, Elly Marcq, Adrian Covaci, Ken Op de Beeck, Jan P van Meerbeeck, Jo Raskin, Annelies Janssens, Annemiek Snoeckx, Kevin Lamote Abstract Objectives: Pleural mesothelioma (PM) is an aggressive thoracic cancer related to historical exposure to asbestos fibres. Symptoms often appear at an advanced stage,…

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Cytopathologic Features of Metastatic Malignant Mesothelioma With SMARCB1 (INI-1) Deficient Diagnosed by Ultrasound-Guided Fine-Needle Aspiration: A Case Report

Diagnostic Cytopathology 2025 December 29 [Link] Jun Yang, Juandi Liu, Jing Jin, Deng Pan, Lei Shao Abstract Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses…

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Cytopathologic Features of Metastatic Malignant Mesothelioma With SMARCB1 (INI-1) Deficient Diagnosed by Ultrasound-Guided Fine-Needle Aspiration: A Case Report

Diagnostic Cytopathology 2025 December 29 [Link] Jun Yang, Juandi Liu, Jing Jin, Deng Pan, Lei Shao Abstract Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses…

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Pleural Mesothelioma Diagnosis for the Pulmonologist: Steps Along the Way

Cancers 2025 December 1 [Link] Alberto Fantin, Nadia Castaldo, Ernesto Crisafulli, Giulia Sartori, Filippo Patrucco, Horiana B Grosu, Paolo Vailati, Giuseppe Morana, Vincenzo Patruno, Stefano Kette, Avinash Aujayeb, Aleš Rozman Abstract Background/Objectives: Malignant pleural mesothelioma (MPM) is a rare, aggressive tumor with a poor prognosis and complex diagnostic pathways. Pulmonologists often play a central role…

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Positron emission tomography/computed tomography in risk-factor-negative young female with malignant pleural mesothelioma: A case report and review of literature

World Journal of Clinical Cases 2025 November 16 [Link] Aikedan Aisikaer, Mo-Mo Sun, Jie Shen Abstract Background: Malignant pleural mesothelioma (MPM), a rare aggressive malignancy, is primarily caused by asbestos exposure. MPM typically affects older adults (median age, 76 years), is uncommon in those under age 50 years and shows male predominance. Based on the…

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Prospective Analysis of Mesotheliomas in Subjects with BAP1 Cancer Syndrome: Clinical Characteristics and Epigenetic Correlates of Disease

Journal of Thoracic Oncology 2025 August 5 [Link] Xinwei Wu, Frank-Villa Hernandez, Haitao Wang, Ruihong Wang, Stephanie Shiffka, Niharika Shah, Shamus R Carr, Chuong D Hoang, Andrew M Blakely, Alexandra Lebensohn, Keerti Mihsra, Sichuan Xi, Mary R Zhang, Tuana Tolunay, Sudheer Gara, Amanda Absher, Deneise Francis, Amanda Rowland, Maureen Connolly, Stephanie Jacobs, Sandra Orfgen, Kevin…

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