IL-7 is expressed in malignant mesothelioma and has a prognostic value

September 21, 2022

Molecular Oncology 2022 August 28 [Link] Hoa-Le Mai, Sophie Deshayes, Thi-Van-Ha Nguyen, Virginie Dehame, Anne-Laure Chéné, Sophie Brouard, Christophe Blanquart Abstract Malignant pleural mesothelioma (MPM) is an aggressive cancer mainly related to asbestos exposure. Despite recent therapeutic advances, notably immunotherapies, the benefit remains limited and restricted to a small percentage of patients. Thus, a better…

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The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy.

January 2, 2019

Front Med 2018 November 30 [Link] Gardner JK, Jackaman C, Mamotte CDS, Nelson DJ Abstract/h3> Aging is associated with an increased incidence of cancer. One contributing factor could be modulation of immune cells responsible for anti-tumor responses, such as dendritic cells (DCs) and T cells. These immunological changes may also impact the efficacy of cancer…

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Biomarkers for Predicting Malignant Pleural Mesothelioma in a Mexican Population.

July 19, 2018

International Journal of Medical Sciences 2018 June 4 [Link] Aguilar-Madrid G, Pesch B, Calderón-Aranda ES, Burek K, Jiménez-Ramírez C, Juárez-Pérez CA, Ochoa-Vázquez MD, Torre-Bouscoulet L, Acosta-Saavedra LC, Sada-Ovalle I, García-Figueroa J, Alvarado-Cabrero I, Castillo-González P, Báez-Saldaña AR, Pérez-Padilla JR, Osnaya-Juárez J, Rivera-Rosales RM, García-Bazán EM, Bautista-Aragón YL, Lazcano-Hernandez E, Munguía-Canales DA, Argote-Greene LM, Taeger D,…

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The characteristics of asbestos-related disease claims made to the Korea Workers’ Compensation and Welfare Service (KCOMWEL) from 2011 to 2015.

July 18, 2018

Annals of Occupational and Environmental Medicine 2018 July 11 [Link] An YS, Kim HD, Kim HC, Jeong KS, Ahn YS Abstract BACKGROUND: This study aimed to enhance understanding of the epidemiologic characteristics of asbestos-related diseases, and to provide information that could inform policy-making aimed at prevention and compensation for occupational asbestos exposure, through analyzing asbestos-related…

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Pirfenidone decreases mesothelioma cell proliferation and migration via inhibition of ERK and AKT and regulates mesothelioma tumor microenvironment in vivo.

July 5, 2018

Scientific Reports 2018 July 3 [Link] Li C, Rezov V, Joensuu E, Vartiainen V, Rönty M, Yin M, Myllärniemi M, Koli K Abstract Malignant mesothelioma is an aggressive cancer with poor prognosis. It is characterized by prominent extracellular matrix, mesenchymal tumor cell phenotypes and chemoresistance. In this study, the ability of pirfenidone to alter mesothelioma…

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A Case of Malignant Pleural Mesothelioma with Bone Marrow Metastases

April 12, 2018

Internal Medicine 2018 March [Epub ahead of print] [Link] Ihara H, Harada N, Shimada N, Kanamori K, Hayashi T, Uekusa T, Takahashi K Abstract A 64-year-old man with the bone marrow metastasis due to malignant pleural mesothelioma (MPM) was diagnosed with anemia, leukoerythroblastosis, thrombocytopenia, and lower back pain. A bone marrow biopsy demonstrated infiltrative malignant…

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Surfing on unreliable waters. A cross-sectional study into the content and quality of online informational resources for mesothelioma patients

February 9, 2018

Patient Education and Counseling 2018 January 29 [Epub ahead of print] [Link] Soloukey Tbalvandany SS, Maat AAPWM, Cornelissen RR, Nuyttens JJJME, Takkenberg JJJM Abstract OBJECTIVE: Malignant Mesothelioma (MM) is a rare asbestos related disease mostly diagnosed in low-skilled patients. The decision-making process for MM treatment is complicated, making an adequate provision of information necessary. The…

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