Radiotherapy
Radiation Induced Abscopal Effect in a Patient With Malignant Pleural Mesothelioma on Pembrolizumab
Cureus 2022 February 12 [Link] Rebekah Rittberg, Elisa Chan, Stephen Yip, Deepu Alex, Cheryl Ho Abstract Abscopal effect is a rare phenomenon in which treatment benefit from radiotherapy (RT) is seen outside the target field due to activation of the immune system inducing an anti-tumor effect. This phenomenon has been reported in cancer patients receiving…
Read MoreAn Update on Emerging Therapeutic Options for Malignant Pleural Mesothelioma
Lung Cancer 2022 March 2 [Link] Alexander Davis, Helen Ke, Steven Kao, Nick Pavlakis Abstract The treatment paradigm for malignant pleural mesothelioma (MPM) has changed little in the last 18 years. Radical intent treatment, consisting of surgical resection, radiotherapy and chemotherapy, has been offered to a highly select few; however, there is little randomised evidence…
Read MoreECM Mechanoregulation in Malignant Pleural Mesothelioma
Frontiers in Bioengineering and Biotechnology 2022 February 14 [Link] Valeria Panzetta, Ida Musella, Sabato Fusco, Paolo A Netti Abstract Malignant pleural mesothelioma is a relatively rare, but devastating tumor, because of the difficulties in providing early diagnosis and effective treatments with conventional chemo- and radiotherapies. Patients usually present pleural effusions that can be used for…
Read MoreNovel and Future Treatment Options in Mesothelioma: A Systematic Review
International Journal of Molecular Sciences 2022 February 10 [Link] Danijela Štrbac, Vita Dolžan Abstract Mesothelioma is a rare tumor, frequently associated with asbestos exposure, arising from pleura and peritoneum. Traditionally, diagnosis and treatment have been difficult in a clinical setting. The treatment is based on a trimodal approach involving surgery, chemotherapy, and radiotherapy. The introduction…
Read MoreRelationship between exposure to ionizing radiation and mesothelioma risk: A systematic review of the scientific literature and meta-analysis
Cancer Medicine 2022 January 14 [Link] Giovanni Visci, Emanuele Rizzello, Carlotta Zunarelli, Francesco Saverio Violante, Paolo Boffetta Abstract Background: Ionizing radiation and mesothelioma have been examined among personnel employed in nuclear power plant and patients treated by external beam radiation therapy (EBRT). The association is still controversial; the purpose of this review is to summarize…
Read MoreBiological Pathways Associated With the Development of Pulmonary Toxicities in Mesothelioma Patients Treated With Radical Hemithoracic Radiation Therapy: A Preliminary Study
Frontiers in Oncology 2021 December 22 [Link] Sergio Crovella, Alberto Revelant, Elena Muraro, Ronald Rodrigues Moura, Lucas Brandão, Marco Trovò, Agostino Steffan, Paola Zacchi, Giuliano Zabucchi, Emilio Minatel, Violetta Borelli Abstract Radical hemithoracic radiotherapy (RHR), after lung-sparing surgery, has recently become a concrete therapeutic option for malignant pleural mesothelioma (MPM), an asbestos-related, highly aggressive tumor…
Read MoreThe highlights of the 15th international conference of the international mesothelioma interest group – Do molecular concepts challenge the traditional approach to pathological mesothelioma diagnosis?
Lung Cancer 2021 November 6 [Link] Sonja Klebe, Francoise Galateau Salle, Rossella Bruno, Luka Brcic, Heather I Chen-Yost, Marie-Claude Jaurand Abstract Pathology plays an important role in diagnosing mesothelioma since radiological and clinical findings alone cannot distinguish mesothelioma reliably from its many mimics. The long-held gold standard for pathological diagnosis requires a tissue biopsy that,…
Read MoreAnticancer agent α-sulfoquinovosyl-acylpropanediol enhances the radiosensitivity of human malignant mesothelioma in nude mouse models
Journal of Radiation Research 2021 November 5 [Link] Eiko Inamasu, Tomoshi Tsuchiya, Motohiro Yamauchi, Kodai Nishi, Katsuya Matsuda, Fumio Sugawara, Kengo Sakaguchi, Ryoichi Mori, Keitaro Matsumoto, Takuro Miyazaki, Go Hatachi, Ryoichiro Doi, Hironosuke Watanabe, Koichi Tomoshige, Naoki Matsuda, Yoshikazu Higami, Isao Shimokawa, Masahiro Nakashima, Takeshi Nagayasu Abstract Malignant pleural mesothelioma (MPM) is a highly malignant…
Read MoreGOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma
World Journal of Clinical Oncology 2021 August 24 [Link] Javier Luna, Andrea Bobo, Joaquín José Cabrera-Rodriguez, María Pagola, Margarita Martín-Martín, María Ángeles González Ruiz, Miguel Montijano, Aurora Rodríguez, Lira Pelari-Mici, Almudena Corbacho, Marta Moreno, Felipe Couñago Abstract Malignant pleural mesothelioma (MPM) is a rare tumor with poor prognosis and rising incidence. Palliative care is common…
Read MoreGOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma
World Journal of Clinical Oncology 2021 August 24 [Link] Javier Luna, Andrea Bobo, Joaquín José Cabrera-Rodriguez, María Pagola, Margarita Martín-Martín, María Ángeles González Ruiz, Miguel Montijano, Aurora Rodríguez, Lira Pelari-Mici, Almudena Corbacho, Marta Moreno, Felipe Couñago Abstract Malignant pleural mesothelioma (MPM) is a rare tumor with poor prognosis and rising incidence. Palliative care is common…
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