Building a Bridge between Chemotherapy and Immunotherapy in Malignant Pleural Mesothelioma: Investigating the Effect of Chemotherapy on Immune Checkpoint Expression.

International Journal of Molecular Sciences 2019 August 26 [Link] Marcq E, Audenaerde JRV, Waele J, Jacobs J, Loenhout JV, Cavents G, Pauwels P, Meerbeeck JPV, Smits EL Abstract In light of the promising results of immune checkpoint blockade (ICPB) in malignant pleural mesothelioma (MPM), we investigated the effect of different chemotherapeutic agents on the expression…

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Gemcitabine combined with oxaliplatin in pretreated patients with malignant pleural mesothelioma: an observational study

Journal of Occupational Medicine and Toxicology. 2008 Dec 18;3:34. [Link] Xanthopoulos A, Bauer TT, Blum TG, Kollmeier J, Schönfeld N, Serke M. Respiratory Diseases Clinic Heckeshorn, Department of Pneumology, HELIOS Klinikum Emil von Behring, Berlin, Germany. torsten.bauer@helios-kliniken.de. Abstract Background: The aim of this study was to investigate the efficacy and safety of oxaliplatin +/- gemcitabine…

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Long-term mortality from pleural and peritoneal cancer after exposure to asbestos: Possible role of asbestos clearance

International Journal of Cancer. 2008 Jun 4. [Epub ahead of print] [Link] Barone-Adesi F, Ferrante D, Bertolotti M, Todesco A, Mirabelli D, Terracini B, Magnani C. Unit of Cancer Epidemiology, CeRMS and Center for Oncologic Prevention Piemonte, University of Turin, Turin, Italy. Abstract Models based on the multistage theory of carcinogenesis predict that the rate…

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Malignant peritoneal mesothelioma: treatment with maximal cytoreductive surgery plus intraperitoneal chemotherapy

Gastroentérologie Clinique et Biologique. 2007 Oct;31(10):784-8. [Link] Elias D, Bedard V, Bouzid T, Duvillard P, Kohneh-Sharhi N, Raynard B, Goere D. Département de chirurgie générale oncologique; Institut Gustave-Roussy, Villejuif. Abstract Objective: To report survival results in patients with diffuse malignant peritoneal mesothelioma (MPM) treated with maximal cytoreductive surgery followed by immediate intraperitoneal chemotherapy, and to…

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A phase 1 and pharmacokinetic study of gemcitabine and oxaliplatin in patients with solid tumors

Cancer Chemotherapy and Pharmacology. 2005 Nov 19;:1-8 [Epub ahead of print]. [Link]. Hui K. Gan1, Paul L. Mitchell1, Peter Galettis2, Ian D. Davis1, Jonathan Cebon1, Paul de Souza2 and Matthew Links2 (1) Department of Medical Oncology and Ludwig Institute for Cancer Research, Austin Hospital, Level D, 3KZ Building, Studley Road, Heidelberg, Melbourne, VIC, Australia (2) Department of Medical Oncology, St George Hospital and University…

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Raltitrexed-Oxaliplatin combination chemotherapy is inactive as second-line treatment for malignant pleural mesothelioma patients

Lung Cancer. 2005 Jun;48(3):429-34. Epub 2005 Jan 24. [Link] Porta C, Zimatore M, Bonomi L, Imarisio I, Paglino C, Sartore-Bianchi A, Mutti L. Medical Oncology, I.R.C.C.S. San Matteo University Hospital, Piazzale C. Golgi, I-27100 Pavia, Italy. c.porta@smatteo.pv.it Abstract Within a single-institution phase II trial, we investigated the antitumor activity of the Raltitrexed-Oxaliplatin combination as second-line…

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