2022 PSOGI Consensus on HIPEC Regimens for Peritoneal Malignancies: Diffuse Malignant Peritoneal Mesothelioma

Annals of Surgical Oncology 2023 July 23 [Link] Vahan Kepenekian, Olivia Sgarbura, Frederic Marchal, Laurent Villeneuve, Shigeki Kusamura, Marcello Deraco Abstract Background: Diffuse malignant peritoneal mesothelioma (DMPM) is a rare and aggressive primary peritoneal disease, with recommended treatment, in eligible patients, of a combination of complete cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). As…

Read More

Adjuvant dendritic cell-based immunotherapy after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with malignant peritoneal mesothelioma: a phase II clinical trial

Journal for Immunotherapy of Cancer 2023 August [Link] Michelle V Dietz, Katrien L A Quintelier, Job P van Kooten, Nadine L de Boer, Madelief Vink, Alexandra R M Brandt-Kerkhof, Cornelis Verhoef, Yvan Saeys, Joachim G J V Aerts, Marcella Willemsen, Sofie Van Gassen, Eva V E Madsen Abstract Background: Malignant peritoneal mesothelioma (MPM) is an…

Read More

High-Risk Peritoneal Mesothelioma: Does Metronomic Chemotherapy Have a Role?

Indian Journal of Surgical Oncology 2023 June [Link] Praveen Kammar, Niharika Garach, Aditi Bhatt, Jay Anam, Vashisth Maniar, Adwaita Gore, Sanket Mehta Abstract Objective: To evaluate the feasibility, tolerance, and efficacy of OMCT (oral metronomic chemotherapy) after CRS + HIPEC for peritoneal mesothelioma in patients with poor prognostic factors: PCI > 20, incomplete CRS, poor…

Read More

Establishment of a Bayesian network model to predict the survival of malignant peritoneal mesothelioma patients after cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy

International Journal of Hyperthermia 2023 [Link] Yan-Dong Su, Xin Zhao, Ru Ma, Yu-Bin Fu, Zhi-Ran Yang, He-Liang Wu, Yang Yu, Rui Yang, Xin-Li Liang, Xue-Mei Du, Yue Chen, Yan Li Abstract Objectives: To establish a Bayesian network (BN) model to predict the survival of patients with malignant peritoneal mesothelioma (MPM) treated with cytoreductive surgery (CRS)…

Read More

Pressurized intraperitoneal aerosol chemotherapy, reasons for interrupting treatment: a systematic review of the literature

Pleura and Peritoneum 2023 April 19 [Link] Anne-Cecile Ezanno, Brice Malgras, Marc Pocard Abstract Objectives: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) gives encouraging results in the treatment of peritoneal metastasis (PM). The current recommendations require at least 3 sessions of PIPAC. However, some patients do not complete the full treatment course and stop after only 1…

Read More

Cytoreductive surgery (CRS) and heated intraperitoneal chemotherapy (HIPEC) for peritoneal mesothelioma: Canadian practices and outcomes

Journal of Surgical Oncology 2023 May 30 [Link] Melina Deban, Kadhim Taqi, Gregory C Knapp, Mikael Soucisse, Matt Curry, Lucas Sidéris, Pierre Dubé, Maher Al Khaldi, Nicole Jedrzejko, Geoff Porter, Carman Giacomantonio, Trevor Hamilton, Andrea MacNeill, Lloyd Mack, Antoine Bouchard-Fortier Abstract Introduction: Peritoneal mesothelioma (PM) is a rare malignancy originating from the peritoneal lining. Cytoreductive…

Read More

Prognostic role of CD74, CD10 and Ki-67 immunohistochemical expression in patients with diffuse malignant peritoneal mesothelioma: a retrospective study

BMC Cancer 2023 May 5 [Link] Yufei Liang, Chunying Li, Yingying Liu, Liang Tian, Dongliang Yang Abstract Background: Diagnosis and treatment of diffuse malignant peritoneal mesothelioma (DMPM) are still challenging. The aim of the present study was to explore the correlation between CD74, CD10, Ki-67 and clinicopathological parameters, and identify independent prognostic factors of DMPM.…

Read More

Prognostic significance of the immuno-peritoneal cancer index in peritoneal metastatic patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Langenbeck’s Archives of Surgery 2023 May 6 [Link] Yasemin Yildirim, Selman Sokmen, Ali Durubey Cevlik, Tayfun Bisgin, Berke Manoglu, Funda Obuz Abstract Purpose: A valid comparison of immune function among different patients with different primary pathologies or even with different tumour burdens requires the common use of a reliable assessment of the patient’s condition. The…

Read More

Surgical phenotype of patients with peritoneal mesothelioma and a germline mutation

Cancer 2023 April 12 [Link] Yaniv Berger, Meghana Gadiraju, Ankit Dhiman, Katie Gilliam, Buerkley Opalecky, Heather Chen, Maria Helgeson, Oliver S Eng, Aliya N Husain, Michael W Drazer, Hedy L Kindler, Jane E Churpek, Kiran K Turaga Abstract Background: This study aimed to investigate if peritoneal mesothelioma (PM) patients with germline mutations (GM) have distinct…

Read More

Surgical case report: The rare case of incidental retroperitoneal mesothelioma

International Journal of Surgery Case Reports 2023 April [Link] Yat Cheung Chung, Travis Ackermann, Yeu Sheng Ang Abstract Introduction and importance: This is a first reported case of isolated retroperitoneal mesothelioma. Most patients present with symptoms of abdominal pain, distension and weight loss. However, a minority of cases are asymptomatic and are found incidentally on…

Read More