Pleurectomy/decortication
Predictive potential of MRI in differentiating the predominant component in biphasic pleural mesothelioma
European Journal of Radiology 2024 May 26 [Link] Ritu R Gill, William G Richards, Hillary Heiling, Emanuele Mazzola, Yin P Hung, Ravi T Seethamraju, Lucian R Chirieac, Raphael Bueno Abstract Purpose: To assess the potential of apparent diffusion coefficient (ADC) values derived from diffusion weighted (DW) MRI preoperatively to predict the predominant histologic component among…
Read MoreExtended pleurectomy decortication and chemotherapy versus chemotherapy alone for pleural mesothelioma (MARS 2): a phase 3 randomised controlled trial
The Lancet Respiratory Medicine 2024 May 10 [Link] Eric Lim, David Waller, Kelvin Lau, Jeremy Steele, Anthony Pope, Clinton Ali, Rocco Bilancia, Manjusha Keni, Sanjay Popat, Mary O’Brien, Nadza Tokaca, Nick Maskell, Louise Stadon, Dean Fennell, Louise Nelson, John Edwards, Sara Tenconi, Laura Socci, Robert C Rintoul, Kelly Wood, Amanda Stone, Dakshinamoorthy Muthukumar, Charlotte Ingle,…
Read MoreAerostasis to limit air-leak following extended pleurectomy-decortication
European Journal of Cardio-Thoracic Surgery 2024 May 2 [Link] An-Lies Provoost, Andreas Bouckaert, Cedric Vanluyten, Annalisa Barbarossa, Kristiaan Nackaerts, Birgit Weynand, Johan Coolen, Sofian Bouneb, Olivia Theisen-Lauk, Isabelle Opitz, Philippe Nafteux, Laurens J Ceulemans Abstract Extended pleurectomy-decortication is a cytoreductive surgical treatment for malignant pleural mesothelioma. Prolonged air-leak remains a major postoperative challenge lengthening hospital…
Read MoreRisk factors influencing postoperative pleural empyema in patients with pleural mesothelioma: a retrospective single-centre analysis
European Journal of Cardiothoracic Surgery 2024 March 29 [Link] Peter Henschke, Laura Chiara Guglielmetti, Sven Hillinger, Gian-Marco Monsch, Didier Schneiter, Isabelle Opitz, Olivia Lauk Abstract Objectives: Postoperative empyema is a severe, potentially lethal complication also present, but poorly studied in patients undergoing surgery for pleural mesothelioma. We aimed to analyse which perioperative characteristics might be…
Read MoreCirculating SMRP and CA-125 before and after pleurectomy decortication for pleural mesothelioma
Thoracic Cancer 2024 April 16 [Link] Juuso Paajanen, Ahmed Sadek, William G Richards, Yue Xie, Emanuele Mazzola, Kristina Sidopoulos, John Kuckelman, Ritu R Gill, Raphael Bueno Abstract Background: Tumor recurrence remains the main barrier to survival after surgery for pleural mesothelioma (PM). Soluble mesothelin-related protein (SMRP) and cancer antigen 125 (CA-125) are established blood-based biomarkers…
Read MoreInvestigation of the appropriate viscosity of fibrinogen in repairing pleural defects using ventilation and anchoring in an ex vivo pig model
Journal of Cardiothoracic Surgery 2024 March 21 [Link] Akihiro Fukuda, Masaki Hashimoto, Yoshitaka Takegawa, Nobuyuki Kondo, Seiki Hasegawa Abstract Objective: Our previous study revealed that the viscosity of fibrinogen could influence the effectiveness of ventilation and anchoring (V/A) methods for controlling air leakages. Here, we examined the association between the viscosity of fibrinogen and effectiveness…
Read MoreA case of attempted transbronchial spigot insertion for fistulous pyothorax in the residual pleural airspace after pleurectomy/decortication for malignant pleural mesothelioma
Respirology Case Reports 2024 January 24 [Link] Ryo Miyata, Shoichiro Morizono, Tadashi Umehara, Aya Harada-Takeda, Go Kamimura, Masaya Aoki, Toshiyuki Nagata, Kazuhiro Ueda Abstract Pleurectomy/decortication for malignant pleural mesothelioma is a relatively recent surgical approach for which there is a dearth of information on complications, especially in the late postoperative period. A 70-year-old man was…
Read MoreExtended pleurectomy/decortication and hyperthermic intraoperative intrapleural cisplatin perfusion for malignant pleural mesothelioma
JTCVS Open 2023 September 14 [Link] Kenichi Okubo, Hironori Ishibashi, Ryo Wakejima, Shunichi Baba, Ayaka Asakawa, Hiroshi Seshima Abstract Objective: To evaluate the efficacy of multimodality treatment including extended pleurectomy/decortication (P/D) and hyperthermic intraoperative chemotherapy (HIOC) with cisplatin for malignant pleural mesothelioma (MPM), we investigated the pharmacokinetics of platinum, adverse events after HIOC, and survival…
Read MoreLong-Term Survival Analysis of Pleural Mesothelioma Patients Undergoing Surgery: Brief Report From a Tertiary Referral Centre
Clinical Lung Cancer 2023 October 24 [Link] Riccardo Orlandi, Giovanni Leuzzi, Luigi Rolli, Michele Ferrari, Alessia Stanzi, Camilla Valsecchi, Ugo Pastorino Abstract Objectives: to date, no consensus has been reached on the surgical gold-standard in pleural mesothelioma (PM). We retrospectively reviewed our experience as a tertiary referral centre, to compare short- and long-term survival of…
Read MoreSalvage pleurectomy/decortication following immunotherapy for malignant pleural mesothelioma
Interdisciplinary Cardiovascular and Thoracic Surgery 2023 November 15 [Link] Masaru Takenaka, Koji Kuroda, Katsuma Yoshimatsu, Masataka Mori, Masatoshi Kanayama, Akihiro Taira, Taiji Kuwata, Fumihiro Tanaka Abstract Salvage surgery following immunotherapy is a promising treatment option for advanced malignant tumour. However, only a few cases of salvage surgery for malignant pleural mesothelioma (MPM) have been reported.…
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