Thoracic Cancer 2021 February 2 [Link] Takafumi Fukui, Takako Okubo, Naoki Tanimoto, Hiromichi Okuma, Yoshitaka Shiina, Mizuki Kohama, Jun Yamada, Yasuhiro Funada, Yoshihiro Ikura Abstract Here, we report a case of malignant pleural mesothelioma (MPM) that was very difficult to diagnose. A 62-year-old woman with a surgical history of recurrent bilateral pneumothorax was admitted to…

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Cancers 2020 December 20 [Link] Roberta Affatato, Paolo Mendogni, Alessandro Del Gobbo, Stefano Ferrero, Francesca Ricci, Massimo Broggini, Lorenzo Rosso Abstract Background: Malignant pleural mesothelioma (MPM) is a very aggressive tumor originating from mesothelial cells. Although several etiological factors were reported to contribute to MPM onset, environmental exposure to asbestos is certainly a major risk…

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Human Pathology 2020 September 2 [Link] Sarita Prabhakaran, Ashleigh Hocking, Chankyung Kim, Matthew Hussey, Sonja Klebe Abstract Malignant pleural mesothelioma is associated with asbestos exposure and poor outcomes. The usefulness of immunohistochemistry for diagnosis of sarcomatoid mesothelioma, especially the desmoplastic type, is limited, and more effective markers are required. GATA binding protein 3 (GATA3) has…

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Clinical Lung Cancer 2020 July 3 [Link] Diego Cortinovis, Federica Grosso, Luciano Carlucci, Paolo Andrea Zucali, Giulia Pasello, Marcello Tiseo, Francesca Sperandi, Lital Hollander, Francesca Galli, Valter Torri, Eliana Rulli, Stefania Canova, Antonio Maconi, Paolo Bidoli, Giovanni Luca Ceresoli , Maurizio D’Incalci, ATREUS investigators Abstract Introduction: New therapeutic approaches in unresectable malignant pleural mesothelioma (MPM)…

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BMC Research Notes 2020 July 29 [Link] Martin Lehnert, Daniel G Weber, Dirk Taeger, Irina Raiko, Jens Kollmeier, Susann Stephan-Falkenau, Thomas Brüning, Georg Johnen, MoMar-Study Group Abstract Objective: Calretinin is a well-known immunohistochemical tissue marker in the diagnosis of malignant mesothelioma. Promising results also indicate the use in early detection. In the present cross-sectional survey,…

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Journal of Breath Research 2020 July 30 [Link] Liam David Little, Vikki Amanda Carolan, K Elizabeth Allen, Laura Margaret Cole, Sarah Louise Haywood-Small Abstract Malignant mesothelioma (MM) is an incurable cancer. MM is often misdiagnosed, with a poor 5-year survival and limited treatment options. The discovery of endogenous volatile organic compounds (VOCs) is required in…

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Respiratory Research 2020 July 16 [Link] Masataka Kojima, Kazunori Kajino, Shuji Momose, Nadila Wali, May Thinzar Hlaing, Bo Han, Liang Yue, Masaaki Abe, Tomoaki Fujii, Katsuhisa Ikeda, Okio Hino Abstract Background: Mesothelioma is histologically divided into three subgroups: epithelioid, sarcomatoid, and biphasic types. The epithelioid or sarcomatoid type is morphologically defined by polygonal or spindle-like…

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Cancer Cytopathology 2020 July 17 [Link] Martin Chevrier, Sara E Monaco, Jacob A Jerome, Francoise Galateau-Salle, Andrew Churg, Sanja Dacic Abstract Background: A number of ancillary tests have been developed that aid in the diagnosis of mesothelioma in cytology specimens. The aim of this retrospective study was to determine whether testing for BAP1 and CDKN2A/p16…

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Thoracic Cancer 2020 May 28 [Link] Takaya Ikeda, Shinnosuke Takemoto, Hiroaki Senju, Hiroshi Gyotoku, Hirokazu Taniguchi, Midori Shimada, Yosuke Dotsu, Yasuhiro Umeyama, Hiromi Tomono, Takeshi Kitazaki, Masaaki Fukuda, Hiroshi Soda, Hiroyuki Yamaguchi, Minoru Fukuda, Hiroshi Mukae Abstract Background: The aim of this study was to assess the efficacy and safety of amrubicin for previously treated…

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