Metformin Induces Apoptosis and Inhibits Notch1 in Malignant Pleural Mesothelioma Cells

February 12, 2021 | Comments Off on Metformin Induces Apoptosis and Inhibits Notch1 in Malignant Pleural Mesothelioma Cells

Frontiers in Cell and Development Biology 2021 January 18 [Link] Marika Rossini, Fernanda Martini, Elena Torreggiani, Francesca Fortini, Giorgio Aquila, Francesco Vieceli Dalla Sega, Simone Patergnani, Paolo Pinton, Pio Maniscalco,…

Malignant pleural mesothelioma in a patient with pneumothorax: A cumbersome subtype both clinically and pathologically

February 11, 2021 | Comments Off on Malignant pleural mesothelioma in a patient with pneumothorax: A cumbersome subtype both clinically and pathologically

Thoracic Cancer 2021 February 2 [Link] Takafumi Fukui, Takako Okubo, Naoki Tanimoto, Hiromichi Okuma, Yoshitaka Shiina, Mizuki Kohama, Jun Yamada, Yasuhiro Funada, Yoshihiro Ikura Abstract Here, we report a case…

STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells

February 10, 2021 | Comments Off on STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells

Translational Oncology 2021 January 30 [Link] Astrid Murumägi, Daniela Ungureanu, Mariliina Arjama, Ralf Bützow, Jouko Lohi, Hannu Sariola, Jukka Kanerva, Minna Koskenvuo, Olli Kallioniemi Abstract Genetic rearrangements involving the anaplastic…

Switch-maintenance gemcitabine after first-line chemotherapy in patients with malignant mesothelioma (NVALT19): an investigator-initiated, randomised, open-label, phase 2 trial

February 9, 2021 | Comments Off on Switch-maintenance gemcitabine after first-line chemotherapy in patients with malignant mesothelioma (NVALT19): an investigator-initiated, randomised, open-label, phase 2 trial

The Lancet Respiratory Medicine 2021 January 27 [Link] Cornedine J de Gooijer, Vincent van der Noort, Jos A Stigt, Paul Baas, Bonne Biesma, Robin Cornelissen, Nico van Walree, Robbert C…

Rucaparib in patients with BAP1-deficient or BRCA1-deficient mesothelioma (MiST1): an open-label, single-arm, phase 2a clinical trial

February 8, 2021 | Comments Off on Rucaparib in patients with BAP1-deficient or BRCA1-deficient mesothelioma (MiST1): an open-label, single-arm, phase 2a clinical trial

The Lancet Respiratory Medicine 2021 January 27 [Link] Dean A Fennell, Amy King, Seid Mohammed, Amy Branson, Cassandra Brookes, Liz Darlison, Alan G Dawson, Aarti Gaba, Margaret Hutka, Bruno Morgan,…

Unusual radiologic presentations of malignant peritoneal mesothelioma

February 5, 2021 | Comments Off on Unusual radiologic presentations of malignant peritoneal mesothelioma

World Journal of Radiology 2020 December 28 [Link] Paul Hendrick Sugarbaker, James S Jelinek Abstract Background: Malignant peritoneal mesothelioma is an unusual disease process characterized radiologically by ascites and infiltration…

Clinical prognostic factors in pleural mesothelioma: best supportive care and anti-tumor treatments in a real-life setting

February 4, 2021 | Comments Off on Clinical prognostic factors in pleural mesothelioma: best supportive care and anti-tumor treatments in a real-life setting

Acta Oncologica 2021 January 27 [Link] Thomas Ringgaard Petersen, Vasiliki Panou, Christos Meristoudis, Ulla Møller Weinreich, Oluf Dimitri Røe Abstract Background: This study aims to investigate patient- and disease characteristics…

Recurrence of mesothelioma after a macroscopic complete resection procedure: is a second radical surgery justified?

February 3, 2021 | Comments Off on Recurrence of mesothelioma after a macroscopic complete resection procedure: is a second radical surgery justified?

Interactive Cardiovascular and Thoracic Surgery 2021 January 26 [Link] Hany Hasan Elsayed, Aly Sherif Hassaballa, Taha Aly Ahmed, Hazem Youssef Sharkawy Abstract A best evidence topic was written according to…

Higher concordance of PD-L1 expression between biopsies and effusions in epithelioid than in nonepithelioid pleural mesothelioma

February 2, 2021 | Comments Off on Higher concordance of PD-L1 expression between biopsies and effusions in epithelioid than in nonepithelioid pleural mesothelioma

Cancer Cytopathology 2021 January 25 [Link] Mohammed S I Mansour, Tomas Seidal, Ulrich Mager, Katalin Dobra, Hans Brunnström, Annika Dejmek Abstract Background: Malignant mesothelioma (MM) is a therapy-resistant tumor, often…

Fluorescence in situ hybridization detection of chromosome 22 monosomy in pleural effusion cytology for the diagnosis of mesothelioma

February 1, 2021 | Comments Off on Fluorescence in situ hybridization detection of chromosome 22 monosomy in pleural effusion cytology for the diagnosis of mesothelioma

Cancer Cytopathology 2021 January 25 [Link] Yoshiaki Kinoshita, Makoto Hamasaki, Shinji Matsumoto, Masayo Yoshimura, Ayuko Sato, Tohru Tsujimura, Toshiaki Kamei, Kunimitsu Kawahara, Akinori Iwasaki, Kazuki Nabeshima Abstract Background: Malignant pleural…

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