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Curated Journal Articles on Mesothelioma

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Involvement of the M-CSF/IL-34/CSF-1R Pathway in Malignant Pleural Mesothelioma

Journal for the Immunotherapy of Cancer 2020 June [Link] Thibaut Blondy, Sènan Mickael d’Almeida, Tina Briolay, Julie Tabiasco, Clément Meiller, Anne-Laure Chéné, Laurent Cellerin, Sophie Deshayes, Yves Delneste, Jean-François Fonteneau, Nicolas Boisgerault, Jaafar Bennouna, Marc Grégoire, Didier Jean, Christophe Blanquart Abstract Background: Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer related to asbestos […]

July 8, 2020

Causation, Full Archive, Pleural, Pleural Effusion
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Cellular Immunotherapy and Locoregional Administration of CAR T-Cells in Malignant Pleural Mesothelioma

Frontiers in Oncology 2020 June 3 [Link] Robert A Belderbos, Heleen Vroman, Joachim G J V Aerts Abstract Malignant pleural mesothelioma (MPM) is a treatment recalcitrant tumor with a poor overall survival (OS). Current approved treatment consists of first line chemotherapy that only modestly increases OS, illustrating the desperate need for other treatment options in […]

July 7, 2020

Chemotherapy, Full Archive, Pleural
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Genomic Profiling of Multiple Primary Cancers Including Synchronous Lung Adenocarcinoma and Bilateral Malignant Mesotheliomas: Identification of a Novel BAP1 Germline Variant

Pathology International 2020 June 24 [Link] Aya Shinozaki-Ushiku, Shinji Kohsaka, Hidenori Kage, Katsutoshi Oda, Kiyoshi Miyagawa, Jun Nakajima, Hiroyuki Aburatani, Hiroyuki Mano, Tetsuo Ushiku Abstract We report a case with a rare combination of synchronous lung adenocarcinoma and bilateral malignant pleural mesotheliomas in a 70-year-old male without asbestos exposure. He metachronously developed peritoneal malignant mesothelioma, […]

July 6, 2020

Full Archive, Immunohistochemistry or IHC, Peritoneal (Abdominal Mesothelioma), Pleural, Type of Mesothelioma:
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NLRP3 and CARD8 Polymorphisms Influence Risk for Asbestos-Related Diseases

Journal of Medical Biochemistry 2020 January 10 [Link] Alenka Franko, Katja Goricar, Viljem Kovac, Metoda Dodic-Fikfak, Vita Dolzan Abstract Background: This study aimed to investigate the association between NLRP3 rs35829419 and CARD8 rs2043211 polymorphisms and the risk of developing pleural plaques, asbestosis, and malignant mesothelioma (MM), and to study the influence of the interactions between […]

July 3, 2020

Causation, Full Archive, Pleural
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Secondary Renal Amyloidosis Associated With Asbestos-Related Pleuropulmonary Diseases

CEN Case Reports 2020 June 13 [Link] Ryoko Shibata, Tomomi Ozaki, Kazuhiro Tada, Takashi Aoyama, Maho Watanabe, Naoko Himuro, Koji Takahashi, Kenji Ito, Tetsuhiko Yasuno, Katsuhisa Miyake, Kosuke Masutani, Noriko Uesugi, Kazuki Nabeshima, Hitoshi Nakashima Abstract Here, we present a 67-year-old Japanese man who developed insidious-onset nephrotic syndrome. He had a history of occupational asbestos […]

July 2, 2020

Causation, CT or CAT scan, Full Archive, Occupational Asbestos Exposure, Pleural Effusion
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NTRK and ALK Rearrangements in Malignant Pleural Mesothelioma, Pulmonary Neuroendocrine Tumours and Non-Small Cell Lung Cancer

Lung Cancer 2020 May 24 [Link] Jose Luis Leal, Geoffrey Peters, Marcin Szaumkessel, Trishe Leong, Khashayar Asadi, Gareth Rivalland, Hongdo Do, Clare Senko, Paul L Mitchell, Chai Zi Quing, Alexander Dobrovic, Bibhusal Thapa, Thomas John Abstract Objectives: Gene rearrangements involving NTRK1, NTRK2, NTRK3, ROS1 and ALK have been identified in many types of cancer, including […]

July 1, 2020

Full Archive, Immunohistochemistry or IHC, Lung Cancer, Pleural
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Genomic-based Ancillary Assays Offer Improved Diagnostic Yield of Effusion Cytology With Potential Challenges in Malignant Pleural Mesothelioma

Pathology International 2020 June 15 [Link] Yoshiaki Kinoshita, Makoto Hamasaki, Shinji Matsumoto, Masayo Yoshimura, Ayuko Sato, Tohru Tsujimura, Toshiaki Kamei, Kunimitsu Kawahara, Kazuki Nabeshima Abstract BRCA1-associated protein 1 (BAP1) or methylthioadenosine phosphorylase (MTAP) immunohistochemistry (IHC) or 9p21 fluorescence in situ hybridization (FISH) are useful for the diagnosis of malignant pleural mesothelioma (MPM). However, the effect […]

June 29, 2020

effusion cytology, Full Archive, Immunohistochemistry or IHC, Pleural, Pleural Effusion
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Addition of Radiotherapy to Surgery and Chemotherapy Improves Survival in Localized Malignant Pleural Mesothelioma: A Surveillance, Epidemiology, and End Results (SEER) Study

Lung Cancer 2020 May 30 [Link] Andrew B Thompson, Thomas J Quinn, Zaid A Siddiqui, Muayad F Almahariq, Inga S Grills, Craig W Stevens Abstract Introduction: Malignant pleural mesothelioma (MPM) is a devastating disease with poor survival outcomes for most patients. Optimizing therapeutic approaches is thus vital, but has been hampered by a dearth of […]

June 26, 2020

Chemotherapy, Full Archive, Pleural, Radiation, Radiotherapy, Surgery
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Role of Inflammation in the Malignant Transformation of Pleural Mesothelial Cells Induced by Multi-Walled Carbon Nanotubes

Nanotoxicology 2020 June 23 [Link] Xiaopei Huang, Yijun Tian, Wenjing Shi, Jikuai Chen, Lang Yan, Lijun Ren, Xiaofang Zhang, Jiangbo Zhu Abstract Multi-walled carbon nanotubes (MWCNTs) are one of the most widely used types of novel nano-fiber materials. The aim of this study was to establish an experimental system based on actual exposure dosage and […]

June 25, 2020

Full Archive, Nanotubes, Nanofibers, Pleural
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Impairments in Bowel Function, Social Function and Quality of Life After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Annals of Surgical Oncology 2020 January [Link] Zubair Bayat, Emily L Taylor, Danielle A Bischof, J Andrea McCart, Anand Govindarajan Abstract Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) can be associated with decreases in quality of life (QOL). Bowel-related QOL (BR-QOL) after CRS-HIPEC has not been previously studied. The objectives of the current study […]

June 17, 2020

Full Archive, Intraperitoneal Chemotherapy, Surgery
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