Symptoms & Symptom Management
IL-7 is expressed in malignant mesothelioma and has a prognostic value
Molecular Oncology 2022 August 28 [Link] Hoa-Le Mai, Sophie Deshayes, Thi-Van-Ha Nguyen, Virginie Dehame, Anne-Laure Chéné, Sophie Brouard, Christophe Blanquart Abstract Malignant pleural mesothelioma (MPM) is an aggressive cancer mainly related to asbestos exposure. Despite recent therapeutic advances, notably immunotherapies, the benefit remains limited and restricted to a small percentage of patients. Thus, a better…
Read MoreMalignant Peritoneal Mesothelioma Presenting with High Protein, High Serum-Ascites Albumin Gradient
Case Reports Cureus 2022 July 26 [Link] Zachary P Kerosky, Charleston R Powell, Phillip C Lindholm Abstract Mesothelioma is a difficult-to-detect neoplasm that rarely develops in the peritoneum. In patients with unexplained ascites, pleural fluid analysis and ultrasonography is often the first step to achieving a diagnosis. This case report shares a unique presentation in…
Read MoreDiagnostic capacity of BAP1 and MTAP in cytology from effusions and biopsy in mesothelioma
Journal of the American Society of Cytopathology 2022 July 9 [Link] Louise Andersen Lynggård, Vasiliki Panou, Weronika Szejniuk, Oluf Dimitri Røe, Christos Meristoudis Abstract Introduction: Serous effusion is often the first sign of mesothelioma. Diagnosis based on cytologic material from the effusions remains controversial and complementary biopsy is usually required. However, obtaining representative tissue sample…
Read MoreClinical significance of 9P21 gene combined with BAP1 and MTAP protein expression in diagnosis and prognosis of mesothelioma serous effusion
Biomedical Reports 2022 June 7 [Link] Guan-Ying Ma, Shuai Shi, Ping Wang, Xing-Guang Wang, Zhi-Gang Zhang Abstract The diagnostic value of the 9P21 gene determined using fluorescence in situ hybridization (FISH) combined with BRCA1-associated protein 1 (BAP1) and methylthioadenosine phosphorylase (MTAP) expression detection by immunohistochemistry, was investigated in serous effusion samples of malignant mesothelioma. A…
Read MoreRapid diagnosis of malignant pleural mesothelioma and its discrimination from lung cancer and benign exudative effusions using blood serum
Biochimica et Biophysica Acta 2022 June 23 [Link] Dilek Yonar, Mete Severcan, Rafig Gurbanov, Abdulsamet Sandal, Ulku Yilmaz, Salih Emri, Feride Severcan Abstract Malignant pleural mesothelioma (MPM), an aggressive cancer associated with exposure to fibrous minerals, can only be diagnosed in the advanced stage because its early symptoms are also connected with other respiratory diseases.…
Read MoreUnexplained Pleural Effusion Leads to the Revelation of a Malignant Mesothelioma: A Case Report
Cureus 2022 April 25 [Link] Meriem Rhazari, Othman Moueqqit, Sara Gartini, Sanae El Morabit, Safae Diani, Mohammed Aharmim, Afaf Thouil, Hatim Kouismi, Jamal Eddine El Bourkadi Abstract Malignant mesothelioma is a rare and aggressive cancer that usually affects subjects with prior asbestos exposure, a major risk factor that has been widely known as carcinogenic, and…
Read MoreUpdate of pathological diagnosis of pleural mesothelioma using genomic-based morphological techniques, for both histological and cytological investigations
Pathology International 2022 May 21 [Link] Kazuki Nabeshima, Makoto Hamasaki, Yoshiaki Kinoshita, Shinji Matsumoto, Prakasit Sa-Ngiamwibool Abstract As more than 80% of pleural mesothelioma (PM) cases start with pleural effusions, diagnosis with effusion smear cytology or pleural biopsy is important. For diagnosing PM, a three-step approach is used: (1) detecting atypical cells; (2) verifying their…
Read More[Primary pleural epithelioid hemangioendothelioma, an often-misdiagnosed rare tumor]
Revue des Maladies Respiratoires 2022 April [Link] P Tossan, E Pichon, F Arbion, D Sizaret, G Simionca, S Marchand-Adam Abstract Introduction: Epithelioid hemangioendothelioma (EHE) is a rare vascular tumor that develops in various organs. Primary pleural epithelioid hemangioendothelioma is an exceptional occurrence, with only forty cases reported in the literature. On account of its rarity,…
Read MoreEvaluation of DNA/RNA quality from cell block of malignant mesothelioma and lung adenocarcinoma
Diagnostic Cytopathology 2022 April 5 [Link] Shigenobu Tatsumi, Mao Takeuchi, Tomomi Fujii, Aya Sugimoto, Yoko Sekita-Hatakeyama, Takeshi Nishikawa, Tomoko Uchiyama, Kohei Morita, Hiroe Itami, Maiko Takeda, Masaharu Yamazaki, Chiho Ohbayashi Abstract Malignant mesothelioma (MM) is a rare and highly lethal tumor that arises from mesothelial tissue on the surface of the chest and abdominal cavity.…
Read MoreECM Mechanoregulation in Malignant Pleural Mesothelioma
Frontiers in Bioengineering and Biotechnology 2022 February 14 [Link] Valeria Panzetta, Ida Musella, Sabato Fusco, Paolo A Netti Abstract Malignant pleural mesothelioma is a relatively rare, but devastating tumor, because of the difficulties in providing early diagnosis and effective treatments with conventional chemo- and radiotherapies. Patients usually present pleural effusions that can be used for…
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