Diagnostic Cytopathology 2022 April 5 [Link] Shigenobu Tatsumi, Mao Takeuchi, Tomomi Fujii, Aya Sugimoto, Yoko Sekita-Hatakeyama, Takeshi Nishikawa, Tomoko Uchiyama, Kohei Morita, Hiroe Itami, Maiko Takeda, Masaharu Yamazaki, Chiho Ohbayashi Abstract Malignant mesothelioma (MM) is a rare and highly lethal tumor that arises from mesothelial tissue on the surface of the chest and abdominal cavity.…

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Frontiers in Bioengineering and Biotechnology 2022 February 14 [Link] Valeria Panzetta, Ida Musella, Sabato Fusco, Paolo A Netti Abstract Malignant pleural mesothelioma is a relatively rare, but devastating tumor, because of the difficulties in providing early diagnosis and effective treatments with conventional chemo- and radiotherapies. Patients usually present pleural effusions that can be used for…

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Internal Medicine Journal 2022 February 21 [Link] L Pairman, Lel Beckert, M Dagger, M J Maze Abstract Background: Cytological examination of pleural fluid has a good specificity but imperfect sensitivity for the diagnosis of malignant pleural effusion (MPE). Published estimates of sensitivity vary and predictors of false negative cytology are not well established. We aimed…

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Lung Cancer 2022 January 6 [Link] Mario Ghosn, Waseem Cheema, Amy Zhu, Jennifer Livschitz, Majid Maybody, Franz E Boas, Ernesto Santos, DaeHee Kim, Jason A Beattie, Michael Offin, Valerie W Rusch, Marjorie G Zauderer, Prasad S Adusumilli, Stephen B Solomon Abstract Objectives: We describe techniques and results of image-guided delivery of mesothelin-targeted chimeric antigen receptor…

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Medicine 2022 January 7 [Link] Takeshi Saraya, Kosuke Ohkuma, Masachika Fujiwara, Haruyuki Ishii Abstract Malignant mesothelioma (MM) is difficult to diagnose because of the lack of parenchymal opacities, often revealing minimal or absent pleural thickening. Furthermore, pleural effusion has diverse differential diagnoses, including malignancies, infections, as well as collagen vascular and other benign diseases. In…

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Lung Cancer 2021 November 6 [Link] Sonja Klebe, Francoise Galateau Salle, Rossella Bruno, Luka Brcic, Heather I Chen-Yost, Marie-Claude Jaurand Abstract Pathology plays an important role in diagnosing mesothelioma since radiological and clinical findings alone cannot distinguish mesothelioma reliably from its many mimics. The long-held gold standard for pathological diagnosis requires a tissue biopsy that,…

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Annals of Medicine and Surgery 2021 November 16 [Link] Saeid Marzban-Rad, Rama Bozorgmehr, Parastesh Sattari, Ghasem Azimi, Ali Azimi Abstract Introduction: and importance: Pulmonary Function Tests (PFTS) is an important tool in the assessment of pulmonary pathologies and preoperative evaluation. Case presentation: A 54-year-old man with history of massive pleurisy in the left thorax, treated…

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Advances in Experimental Medicine and Biology 2021 November 18 [Link] Christian Biancosino, Lea Isabell Shari van der Linde, Guido Sauter, Florian Stellmacher, Marcus Kr├╝ger, Lutz Welker Abstract Malignant mesotheliomas (MM) are rare tumors with high mortality rates, whose incidence varies regionally and nationally, and the diagnosis is difficult. Histology-based diagnosis is considered the gold standard…

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Thoracic Cancer 2021 October 26 [Link] Shu Zhang, Yuan Zhang, Wei Feng, Zhongyue Shi, Huanzhong Shi, Yuhui Zhang Abstract Background: Malignant pleural effusion (MPE) is common in malignant pleural mesothelioma (MPM). The survival of patients with MPM and MPE is heterogeneous. The LENT and BRIMS scores using routine clinical parameters were developed to predict the…

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