Thoracic Cancer 2020 October 8 [Link] Oscar Arrieta, Francisco Lozano-Ruiz, Monika Blake-Cerda, Rodrigo Catalán, Luis Lara-Mejía, Miguel Ángel Salinas, Federico Maldonado-Magos, José F Corona-Cruz Abstract Background: Treatment of malignant pleural mesothelioma (MPM) represents a major challenge for oncologists. Multimodality treatment, which generally involves induction chemotherapy, surgery and radiotherapy have recently shown promising results. The aim…

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Journal of Immunology 2020 September 18 [Link] Mikihiro Kohno, Junichi Murakami, Licun Wu, Mei-Lin Chan, Zhihong Yun, B C John Cho, Marc de Perrot Abstract Increasing evidence indicates that local hypofractionated radiotherapy (LRT) can elicit both immunogenic and immunosuppressive local and systemic immune responses. We thus hypothesized that blockade of LRT-induced immunosuppressive responses could augment…

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Annals of Palliative Medicine 2020 August 14 [Link] Andrew R Barsky, Michele M Kim, Russell Maxwell, Amberly Mendes, Christopher M Wright, Emily J Anstadt, Sally McNulty, Lei Dong, James M Metz, Steven J Feigenberg, Taoran Li, Keith A Cengel Abstract Background: Radiation therapy (RT) can provide effective symptomatic palliation in patients with malignant pleural mesothelioma…

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International Journal of Surgery Case Reports 2020 July 17 [Link] Shigefumi Matsuyama, Tomohiro Imazuru, Masateru Uchiyama, Hiroo Ota, Mitsuru Iida, Tomoki Shimokawa Abstract Introduction: Primary malignant pericardial mesothelioma is a rare tumor that is very difficult to diagnose. Furthermore, it is a lethal disease, because patients usually have progressed at the time of referral. Presentation…

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Lung Cancer 2020 May 30 [Link] Andrew B Thompson, Thomas J Quinn, Zaid A Siddiqui, Muayad F Almahariq, Inga S Grills, Craig W Stevens Abstract Introduction: Malignant pleural mesothelioma (MPM) is a devastating disease with poor survival outcomes for most patients. Optimizing therapeutic approaches is thus vital, but has been hampered by a dearth of…

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Practical Radiation Oncology 2020 February 20 [Link] Patel R, Ludmir EB, Miccio JA, Menon H, Barsky AR, Mesko SM, Kodali M, Lautenschlaeger T, Adeberg S, Simone CB 2nd, Verma V Abstract PURPOSE: To explore the use of intensity-modulated radiotherapy (IMRT) after lung-sparing surgery in malignant pleural mesothelioma (MPM). Because severe toxicities have been documented following…

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BioMed Research International 2019 December 20 [Link] Pehlivan B, Sengul K, Yesil A, Nalbant N, Ozturk O, Ozdemir Y, Topkan E Abstract OBJECTIVE: To compare volumetric arc therapy (VMAT) and helical tomotherapy (HT) plans in terms of dosimetric parameters in positron emission tomography- (PET-) computerized tomography- (CT-) based radiation therapy planning in unresectable malignant pleural…

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International Journal of Ratdiation Oncology, Biology, Physics 2019 November 28 [Link] Jackson MR, Ashton M, Koessinger AL, Dick C, Verheij M, Chalmers AJ Abstract The incidence of mesothelioma continues to rise and prognosis remains dismal due to resistance to conventional therapies and few novel treatment options. Failure to activate apoptotic cell death is a resistance…

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