Tumor Debulking
Multicystic mesothelioma: Operative and long-term outcomes with cytoreductive surgery and hyperthermic intra peritoneal chemotherapy.
European journal of surgical oncology [Link] Nizri E, Baratti D, Guaglio M, Sinukumar S, Cabras A, Kusamura S, Deraco M Abstract BACKGROUND: Multicystic peritoneal mesothelioma (MCPM) is an extremely rare disease with 40-50% rate of recurrence after surgical debulking. Due to the recurrent nature of the disease, the option of cytoreductive surgery combined with hyperthermic…
Read MoreA Case of the Resected Lymphohistiocytoid Mesothelioma: BAP1 Is a Key of Accurate Diagnosis
Anticancer Research 2017 December [Link] Matsubara T Abstract BACKGROUND: Malignant mesothelioma (MM) is a well-known malignant tumor that occurs in the pleura and is histopathologically classified into three subtypes. Lymphohistiocytoid mesothelioma (LHM) is considered a variant of epithelioid MM, and few cases have been reported. First case of LHM was reported by Henderson et al.…
Read MoreSoluble Mesothelin-Related Peptides to Monitor Recurrence After Resection of Pleural Mesothelioma
Oncolytic Viral Therapy for Mesothelioma
Frontiers in Oncology 2017 August 24 [Link] Pease DF, Kratzke RA Abstract The limited effectiveness of conventional therapy for malignant pleural mesothelioma demands innovative approaches to this difficult disease. Even with aggressive multimodality treatment of surgery, radiation, and/or chemotherapy, the median survival is only 1-2 years depending on stage and histology. Oncolytic viral therapy has emerged…
Read MoreRemote Recurrence of Benign Multicystic Peritoneal Mesothelioma
Journal of Obstetrics 2017 July 18 [Epub ahead of print] [Link] Lee CE, Agrawal A Abstract BACKGROUND: Benign peritoneal cystic mesothelioma (BPCM) is a rare disease entity that arises from mesothelioma cells. We describe a rare case of BPCM recurrence 36 years after its initial presentation. CASE: A 62-year-old woman was referred to an outpatient…
Read MoreThe inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells
Stem cell research & therapy 2017 May 25 [Link] Pattarozzi A, Carra E, Favoni RE, Würth R, Marubbi D, Filiberti RA, Mutti L, Florio T, Barbieri F, Daga A Abstract BACKGROUND: Malignant pleural mesothelioma is an aggressive cancer, characterized by rapid progression and high mortality. Persistence of tumor-initiating cells (TICs, or cancer stem cells) after…
Read MoreDiode-Pumped Laser for Lung-Sparing Surgical Treatment of Malignant Pleural Mesothelioma
The Annals of Thoracic Surgery 2017 June [Link] Bölükbas S1, Biancosino C2, Redwan B2, Eberlein M Abstract Surgical resection represents one of the essential cornerstones in multimodal treatment of malignant pleural mesothelioma. In cases of tumor infiltration of the lung, lung-scarifying procedures such as lobectomies or pneumonectomies might be necessary to achieve macroscopic complete resection.…
Read MorePhysical function and health-related quality of life in patients undergoing surgical treatment for malignant pleural mesothelioma
Multinational Association of Supportive Care in Cancer 2017 March [Epub ahead of print] [Link] Tanaka T, Morishita S, Hashimoto M, Itani Y, Mabuchi S, Kodama N, Hasegawa S, Domen K Abstract Malignant pleural mesothelioma (MPM) is a rare cancer that affects the thin cell wall lining of internal organs and structures. Studies have shown that…
Read MoreImpact of tumour thickness on survival after radical radiation and surgery in malignant pleural mesothelioma
The European Respiratory Journal 2017 March 15 [Print 2017] [Link] de Perrot M, Dong Z, Bradbury P, Patsios D, Keshavjee S, Leighl NB, Hope A, Feld R, Cho J Abstract Tumour thickness was assessed to determine if this parameter could refine patients’ selection for multimodality therapy in malignant pleural mesothelioma.We reviewed 65 consecutive treatment-naïve malignant…
Read MoreHMGB1 targeting by ethyl pyruvate suppresses malignant phenotype of human mesothelioma
Oncotarget 2017 February 7 [Epub ahead of print] [Link] Pellegrini L, Xue J1 Larson D, Pastorino S, Jube S, Forest KH, Saad-Jube ZS, Napolitano A, Pagano I, Negi VS, Bianchi ME, Morris P, Pass HI, Gaudino G, Carbone M, Yang H Abstract Human malignant mesothelioma (MM) is an aggressive cancer linked to asbestos and erionite…
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