desmoplastic
Usefulness of Cyclin D1/Podoplanin Dual Immunohistochemical Stain to Differentiate Malignant Mesothelioma From Reactive Mesothelial Proliferations
American Journal of Clinical Pathology 2022 March 14 [Link] Raghavendra Pillappa, Austin Wiles, Sadia Sayeed, Valentina Robila Abstract Objectives: To examine the potential of cyclin D1/podoplanin dual immunohistochemical stain to differentiate malignant mesothelioma from reactive mesothelial proliferations. Methods: Cyclin D1/podoplanin dual immunohistochemistry was performed on 34 surgical cases of reactive mesothelial proliferations, malignant mesothelioma, and…
Read MoreMalignant mesothelioma: A histomorphological and immunohistochemical study of 24 cases from a tertiary care hospital in Southern India.
Indian Journal of Cancer 2018 April-June [Link] Hui M, Uppin SG, Bhaskar K, Kumar NN, Paramjyothi GK Abstract BACKGROUND: Malignant mesotheliomas are histologically heterogeneous neoplasms. Definite diagnosis requires a varied panel of immunohistochemical (IHC) markers to differentiate these from histological mimics. Only a few case series have been reported in the Indian literature where mesotheliomas…
Read MoreGATA3 Immunohistochemistry for Distinguishing Sarcomatoid and Desmoplastic Mesothelioma From Sarcomatoid Carcinoma of the Lung
American Journal of Surgical Pathology 2017 June [Epub ahead of print] [Link] Berg KB, Churg A Abstract The separation of sarcomatoid and desmoplastic malignant mesotheliomas from sarcomatoid carcinomas of the lung metastatic to the pleura may be difficult, since both types of tumor can be morphologically similar and are frequently positive only for pan-keratin. GATA…
Read MoreMalignant mesothelioma of the pleura with desmoplastic histology: a case series and literature review
BMC Cancer 2016 September 6 [Link] Hashimoto K, Okuma Y, Hosomi Y, Hishima T Abstract BACKGROUND: Desmoplastic malignant pleural mesothelioma (DMM) is rare histological subtype of diffuse malignant pleural mesothelioma (MPM), accounting for 5-10 % of cases. It has a poor prognosis, with direct invasion of the chest wall or lungs and distant metastases. Its…
Read MoreA Biphasic Pleural Tumor with Features of an Epithelioid and Small Cell Mesothelioma: Morphologic and Molecular Findings
Case Reports in Pathology [Epub 2016 June 15] [Link] Hackman S, Hammer RD, Layfield L Abstract Abstract Malignant mesotheliomas are generally classified into epithelioid, sarcomatoid, desmoplastic, and biphasic types with rare reports of a small cell form. These small cell variants display some morphologic overlap with desmoplastic small round cell tumors (DSRCTs) which generally occur…
Read MoreImmunohistochemistry of cytokeratins 7, 8, 17, 18, and 19, and GLUT-1 aids differentiation of desmoplastic malignant mesothelioma from fibrous pleuritis
Histology and Histopathology. 2012 Dec 10. [Epub ahead of print] [Link] Horiuchi T, Ogata S, Tominaga S, Hiroi S, Kawahara K, Hebisawa A, Irei I, Ito I, Kameya T, Tsujimura T, Nakano T, Nakanishi K, Kawai T. Department of Pathology and Laboratory Medicine, National Defense Medical College, Tokorozawa. Japan. Abstract It is difficult to distinguish…
Read MoreMalignant pleural mesothelioma
Kyobu Geka. 2007 Jan;60(1):31-4. [Link] Kawamata O, Kondu Y, Murata T, Uetsuka H, Uda M, Nakai H, Ohta T. Department of Surgery, Onomichi Municipal Hospital, Onomichi, Japan. Abstract Malignant pleural mesothelioma carries a poor prognosis, for which no standard therapy has been established. We report 15 cases of malignant pleural mesothelioma experienced since 2000 focusing…
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