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Curated Journal Articles on Mesothelioma

Category Archives: Surgery

Surgery or surgeries used in the treatment of malignant mesothelioma.

Should Lung-Sparing Surgery Be the Standard Procedure for Malignant Pleural Mesothelioma?

Journal of Clinical Medicine 2020 July 8 [Link] Yoshinobu Ichiki, Hidenori Goto, Takashi Fukuyama, Kozo Nakanishi Abstract Background: Surgical procedures for malignant pleural mesothelioma (MPM) include extrapleural pneumonectomy (EPP), extended pleurectomy/decortication (P/D) and P/D. EPP has been applied to MPM for a long time, but the postoperative status is extremely poor due to the loss […]

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Acute kidney injury after cytoreductive surgery and hyperthermic intraoperative cisplatin chemotherapy for malignant pleural mesothelioma

The Journal of Thoracic and Cardiovascular Surgery 2020 May 29 [Link] Tammy Hod, Katherin J Freedberg, Shveta S Motwani, Margaret Chen, Gyorgy Frendl, David E Leaf, Shruti Gupta, Suraj Sarvode Mothi, William G Richards, Raphael Bueno, Sushrut S Waikar Abstract Objectives: Cytoreductive surgery with hyperthermic intraoperative chemotherapy with cisplatin has been used successfully to treat […]

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Clinical Features in Patients With Malignant Pleural Mesothelioma With 5-Year Survival and Evaluation of Original Diagnoses

Clinical Lung Cancer 2020 May 23 [Link] Juuso Paajanen, Sanna Laaksonen, Ilkka Ilonen, Tapio Vehmas, Mikko I Mäyränpää, Eva Sutinen, Eeva Kettunen, Jarmo A Salo, Jari Räsänen, Henrik Wolff, Marjukka Myllärniemi Abstract Introduction: Malignant pleural mesothelioma (MPM) is a fatal malignancy strongly associated with previous asbestos exposure. Overall survival remains dismal, partly owing to poor […]

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TLD1433-Mediated Photodynamic Therapy with an Optical Surface Applicator in the Treatment of Lung Cancer Cells In Vitro

Pharmaceuticals 2020 June 28 [Link] Sarah Chamberlain, Houston D Cole, John Roque 3rd, David Bellnier, Sherri A McFarland, Gal Shafirstein Abstract Intra-operative photodynamic therapy (IO-PDT) in combination with surgery for the treatment of non-small cell lung cancer and malignant pleural mesothelioma has shown promise in improving overall survival in patients. Here, we developed a PDT […]

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Addition of Radiotherapy to Surgery and Chemotherapy Improves Survival in Localized Malignant Pleural Mesothelioma: A Surveillance, Epidemiology, and End Results (SEER) Study

Lung Cancer 2020 May 30 [Link] Andrew B Thompson, Thomas J Quinn, Zaid A Siddiqui, Muayad F Almahariq, Inga S Grills, Craig W Stevens Abstract Introduction: Malignant pleural mesothelioma (MPM) is a devastating disease with poor survival outcomes for most patients. Optimizing therapeutic approaches is thus vital, but has been hampered by a dearth of […]

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Impairments in Bowel Function, Social Function and Quality of Life After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Annals of Surgical Oncology 2020 January [Link] Zubair Bayat, Emily L Taylor, Danielle A Bischof, J Andrea McCart, Anand Govindarajan Abstract Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) can be associated with decreases in quality of life (QOL). Bowel-related QOL (BR-QOL) after CRS-HIPEC has not been previously studied. The objectives of the current study […]

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Localized Biphasic Malignant Mesothelioma Presenting as a Giant Pelvic Wall Mass: A Rare Case Report and Literature Review

BMC Medical Imaging 2020 May 6 [Link] Yunsong Liu, Jingjun Wu, Ying Zhao, Pengxin Zhang, Zhengyu Hua, Wan Dong, Tao Lin, Ailian Liu Abstract Background: Localized biphasic MPeM is rare in clinical practice, we reviewed 8 cases of localized biphasic MPeM (including our present case), and summarized the clinical and imaging features of the disease. […]

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Treatment patterns among patients with malignant pleural mesothelioma: An Italian, population-based nationwide study.

Thoracic Cancer 2020 May 4 [Link] Trama A, Proto C, Signorelli D, Garassino MC, Lo Russo G, Ganzinelli M, Prelaj A, Mensi C, Gangemi M, Gennaro V, Chellini E, Caldarella A, Angelillo IF, Ascoli V, Pascucci C, Tagliabue G, Cusimano R, Bella F, Falcini F, Merler E, Masanotti G, Ziino A, Michiara M, Gola G, […]

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Surgery for Mesothelioma After Radiation Therapy (SMART); A Single Institution Experience.

Frontiers in Oncology 2020 March 24 [Link] Breen WG, Garces YI, Olivier KR, Park SS, Merrell KW, Nichols FC, Peikert TD, Molina JR, Mansfield AS, Roden AC, Blackmon SH, Wigle DA Abstract Background: The optimal treatment sequence for localized malignant pleural mesothelioma (MPM) is controversial. We aimed to assess outcomes and toxicities of treating localized […]

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Surgery for pleural mesothelioma, when it is indicated and why: arguments against surgery for malignant pleural mesothelioma.

Translational Lung Cancer Research 2020 February [Link] Woodard GA, Jablons DM Abstract Extrapleural pneumonectomy (EPP) and pleurectomy decortication (PD) are radical operations for malignant pleural mesothelioma (MPM) that remain controversial among thoracic surgeons. There is a lack of randomized evidence to support a survival benefit when major surgical resection is included in multi-modality treatment regimens. […]

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