Surgery
Recurrence of mesothelioma after a macroscopic complete resection procedure: is a second radical surgery justified?
Interactive Cardiovascular and Thoracic Surgery 2021 January 26 [Link] Hany Hasan Elsayed, Aly Sherif Hassaballa, Taha Aly Ahmed, Hazem Youssef Sharkawy Abstract A best evidence topic was written according to a structured protocol. The question addressed was: In patients with mesothelioma who develop a local recurrence after macroscopic complete resection (MCR) surgery, does performing a…
Read MoreSurgery for malignant pleural mesothelioma after radiotherapy (SMART): final results from a single-centre, phase 2 trial
The Lancet Oncology 2021 January 12 [Link] B C John Cho, Laura Donahoe, Penelope A Bradbury, Natasha Leighl, Shaf Keshavjee, Andrew Hope, Prodipto Pal, Michael Cabanero, Kasia Czarnecka, Karen McRae, Ming-Sound Tsao, Marc de Perrot Abstract Background: A novel approach for managing malignant pleural mesothelioma, surgery for mesothelioma after radiotherapy (SMART), consisting of a short…
Read MoreEstablishment and Characterization of Patient-Derived Xenografts (PDXs) of Different Histology from Malignant Pleural Mesothelioma Patients
Cancers 2020 December 20 [Link] Roberta Affatato, Paolo Mendogni, Alessandro Del Gobbo, Stefano Ferrero, Francesca Ricci, Massimo Broggini, Lorenzo Rosso Abstract Background: Malignant pleural mesothelioma (MPM) is a very aggressive tumor originating from mesothelial cells. Although several etiological factors were reported to contribute to MPM onset, environmental exposure to asbestos is certainly a major risk…
Read MoreClinical features and surgical outcomes of major urological interventions during cytoreductive surgery and hyperthermic intraperitoneal chemotheraphy
Therapeutic Advances in Urology 2020 December 10 [Link] Özgül Düzgün, Murat Kalın, Resul Sobay, Ömer Faruk Özkan Abstract Background: Urinary system resections and reconstructions are needed in peritoneal carcinomatosis due to abdominal malignancies. The effect of hyperthermic intraperitoneal chemotherapy on these urological procedures after reconstruction remains uncertain. The aim of the study is to evaluate…
Read MoreMalignant pleural neoplasm with both differentiation of epithelioid mesothelioma and squamous-cell carcinoma, a rare phenomena
Diagnostic Cytopathology 2020 December 21 [Link] Ashley Re, David Shersher, Ashleigh Allen, Roland Schwarting, Shuyue Ren Abstract Malignant mesothelioma, a neoplasm arising within the serosal surfaces, has been linked closely to asbestos exposure. We present a case of 72-year-old male with a 27 year work-related history of asbestos exposure who presented with dyspnea. Chest computed…
Read MoreThe Impact on Outcome by Adding Bevacizumab to Standard Induction Chemotherapy Prior to Mesothelioma Surgery: A Retrospective Single Center Analysis
Frontiers in Oncology 2020 November 13 [Link] Olivia Lauk, Karina Bruestle, Thomas Neuer, Bianca Battilana, Thi Dan Linh Nguyen, Thomas Frauenfelder, Rolf Stahel, Walter Weder, Alessandra Curioni-Fontecedro, Isabelle Opitz Abstract Objectives: Adding bevacizumab, an anti-Vascular Endothelial Growth Factor (VEGF), to platinum-based chemotherapy/pemetrexed in 1st line treatment of advanced malignant pleural mesothelioma (MPM), significantly improved overall…
Read MorePleurectomy Decortication in the Treatment of Malignant Pleural Mesothelioma: Encouraging Results and Novel Prognostic Implications Based on Experience in 355 Consecutive Patients
Annals of Surgery 2020 December 3 [Link] Moshe Lapidot, Ritu R Gill, Emanuele Mazzola, Samuel Freyaldenhoven, Scott J Swanson, Michael T Jaklitsch, David J Sugarbaker, Raphael Bueno Abstract Objective: We report a series of 355 consecutive patients treated over 9 years in a single institution with intended PDC. Background: Surgery for MPM has shifted from…
Read MoreDiagnostic Laparoscopy Improves Staging of Malignant Pleural Mesothelioma with Routine PET Imaging
Annals of Thoracic Surgery 2020 December 1 [Link] R Taylor Ripley, Nihanth Palivela, Shawn S Groth, Eugene A Choi, Lorraine D Cornwell, Phillip W Carrott, George Van Buren, Taylor G Splawn, David J Sugarbaker, Bryan M Burt Abstract Background: With a multimodal treatment strategy, cytoreductive surgery extends survival in malignant pleural mesothelioma. Improving the accuracy…
Read MoreDiagnostic Laparoscopy Improves Staging of Malignant Pleural Mesothelioma with Routine PET Imaging
Annals of Thoracic Surgery 2020 December 1 [Link] R Taylor Ripley, Nihanth Palivela, Shawn S Groth, Eugene A Choi, Lorraine D Cornwell, Phillip W Carrott, George Van Buren, Taylor G Splawn, David J Sugarbaker, Bryan M Burt Abstract Background: With a multimodal treatment strategy, cytoreductive surgery extends survival in malignant pleural mesothelioma. Improving the accuracy…
Read MoreDistant Cutaneous Metastasis Of Malignant Epithelioid Mesothelioma
Journal of Cutaneous Pathology 2020 November 30 [Link] Katrina Collins, Priyadharsini Nagarajan, Phyu P Aung Abstract Malignant mesothelioma is a locally aggressive malignancy most commonly arising from the pleural and/or peritoneal cavity. Distant cutaneous metastasis is extremely rare. Here, we describe two cases of mesothelioma metastatic to the head and neck skin. Case 1: A…
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