Biomedical Reports 2022 June 7 [Link] Guan-Ying Ma, Shuai Shi, Ping Wang, Xing-Guang Wang, Zhi-Gang Zhang Abstract The diagnostic value of the 9P21 gene determined using fluorescence in situ hybridization (FISH) combined with BRCA1-associated protein 1 (BAP1) and methylthioadenosine phosphorylase (MTAP) expression detection by immunohistochemistry, was investigated in serous effusion samples of malignant mesothelioma. A…

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Targeted Oncology 2022 July 30 [Link] Fatéméh Dubois, Céline Bazille, Jérôme Levallet, Elodie Maille, Solenn Brosseau, Jeannick Madelaine, Emmanuel Bergot, Gérard Zalcman, Guénaëlle Levallet Abstract Malignant pleural mesothelioma is a rare and aggressive neoplasm, which has primarily been attributed to the exposure to asbestos fibers (83% of cases); yet, despite a ban of using asbestos…

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JTO Clinical and Research Reports 2022 June 9 [Link] Takaaki Tanaka, Shoji Asakura, Kazuya Hisamatsu, Nobukazu Fujimoto Abstract A 69-year-old man presented with a pulmonary opacity at a regular medical check-up. He had been exposed to asbestos in a chemical fiber manufacturing setting. Result of positron emission tomography with computed tomography (CT) revealed fluorodeoxyglucose accumulations…

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Journal of Clinical Medicine 2022 June 10 [Link] Alice Bellini, Sara Mazzarra, Sara Sterrantino, Desideria Argnani, Franco Stella Abstract Malignant pleural mesothelioma (MPM) is an aggressive asbestos-related tumour with poor prognosis. To date, a multimodality treatment, including chemotherapy and surgery, with or without radiotherapy, is the gold standard therapy for selected patients with epithelioid and…

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Critical Reviews in Toxicology 2022 June 15 [Link] David M Bernstein Abstract The potential toxic effects of short chrysotile and amphibole asbestos fibers with lengths <5 to ∼10 µm have been debated over the years. This stems from the large database of epidemiology, toxicology, and in-vitro studies, each of which often provides different information in…

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Genes, Chromosomes & Cancer 2022 June 4 [Link] Josephine K Dermawan, Dianne Torrence, Cheng-Han Lee, Liliana Villafania, Kerry A Mullaney, Sara DiNapoli, Purvil Sukhadia, Ryma Benayed, Laetitia Borsu, Narasimhan P Agaram, Garrett M Nash, Brendan C Dickson, Jamal Benhamida, Cristina R Antonescu Abstract Mesothelioma is a rare, aggressive malignant neoplasm of mesothelial origin. A small…

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American Journal of Industrial Medicine 2022 June 1 [Link] Dirk Taeger, Katharina Wichert, Martin Lehnert, Swaantje Casjens, Beate Pesch, Daniel G Weber, Thomas Brüning, Georg Johnen, Thomas Behrens Abstract Background: Asbestos causes mesothelioma and lung cancer. In the European Union, asbestos was banned in 2005, but it is still in use in many other countries.…

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Biological & Pharmaceutical Bulletin 2022 [Link] Ryoko Tomita, Nao Nishijo, Tadashi Hayama, Toshihiro Fujioka Abstract Malignant pleural mesothelioma (MPM) is a malignancy closely associated with asbestos exposure. Although early diagnosis provides a chance of effective treatment and better prognosis, invasive biopsy and cytological procedure are required for definitive diagnosis. In this study, we developed a…

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Expert Review of Clinical Pharmacology 2022 May 15 [Link] Dario P Anobile, Giulia Montenovo, Camilla Pecoraro, Marika Franczak 1 5, Widad Ait Iddouch, Godefridus J Peters, Chiara Riganti, Elisa Giovannetti Abstract Introduction: Malignant mesothelioma (MMe) is an aggressive rare cancer of the mesothelium, associated with asbestos exposure. MMe is currently an incurable disease at all…

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