Occupational Asbestos Exposure
The potential utility of GATA binding protein 3 for diagnosis of malignant pleural mesotheliomas
Human Pathology 2020 September 2 [Link] Sarita Prabhakaran, Ashleigh Hocking, Chankyung Kim, Matthew Hussey, Sonja Klebe Abstract Malignant pleural mesothelioma is associated with asbestos exposure and poor outcomes. The usefulness of immunohistochemistry for diagnosis of sarcomatoid mesothelioma, especially the desmoplastic type, is limited, and more effective markers are required. GATA binding protein 3 (GATA3) has…
Read MoreEvaluation of Nonresponse Bias in a Case-Control Study of Pleural Mesothelioma
International Journal of Environmental Research and Public Health 2020 August 24 [Link] Chiara Airoldi, Daniela Ferrante, Dario Mirabelli, Danila Azzolina, Corrado Magnani Abstract Nonparticipation limits the power of epidemiological studies, and can cause bias. In a case-control study on pleural malignant mesothelioma (MM), we found low participation in interviews (63%) among controls. Our goal was…
Read MoreNew vistas in malignant mesothelioma: MicroRNA architecture and NRF2/MAPK signal transduction
Life Sciences 2020 July 22 [Link] Manav Gandhi, Sujit Nair Abstract Malignant mesothelioma (MM) is a cancer of the mesothelial lining of the pleura, peritoneum, pericardium and testes. The most common form is asbestos-linked MM that is etiologically linked to repeated asbestos exposure with a long latency period, although non-asbestos MM has also been reported.…
Read MoreDual Inhibition of CDK4/6 and PI3K/AKT/mTOR Signaling Impairs Energy Metabolism in MPM Cancer Cells
International Journal of Molecular Sciences 2020 July 21 [Link] Mara Bonelli, Rita Terenziani, Silvia Zoppi, Claudia Fumarola, Silvia La Monica, Daniele Cretella, Roberta Alfieri, Andrea Cavazzoni, Graziana Digiacomo, Maricla Galetti, Pier Giorgio Petronini Abstract Background: Malignant pleural mesothelioma (MPM) is an aggressive malignancy associated to asbestos exposure. One of the most frequent genetic alteration in…
Read MoreSecondary Renal Amyloidosis Associated With Asbestos-Related Pleuropulmonary Diseases
CEN Case Reports 2020 June 13 [Link] Ryoko Shibata, Tomomi Ozaki, Kazuhiro Tada, Takashi Aoyama, Maho Watanabe, Naoko Himuro, Koji Takahashi, Kenji Ito, Tetsuhiko Yasuno, Katsuhisa Miyake, Kosuke Masutani, Noriko Uesugi, Kazuki Nabeshima, Hitoshi Nakashima Abstract Here, we present a 67-year-old Japanese man who developed insidious-onset nephrotic syndrome. He had a history of occupational asbestos…
Read MoreThe epidemiological surveillance of malignant mesothelioma in Italy (1993-2015): methods, findings, and research perspectives.
Epidemiologia e prevenzione 2020 Jan-Feb [Link] Marinaccio A, Corfiati M, Binazzi A, Di Marzio D, Bonafede M, Verardo M, Migliore E, Gennaro V, Mensi C, Schallemberg G, Mazzoleni G, Fedeli U, Negro C, Romanelli A, Chellini E, Grappasonni I, Pascucci C, Madeo G, Romeo E, Trafficante L, Carrozza F, Angelillo IF, Cavone D, Cauzillo G,…
Read MoreMicroRNAs diagnostic and prognostic value as predictive markers for malignant mesothelioma.
Archives of Environmental and Occupational Health 2020 April 20 [Link] Sturchio E, Berardinelli MG, Boccia P, Zanellato M, Gioiosa S Abstract Malignant mesothelioma is an aggressive tumor resistant to current therapies with a latency period ranging between 20 and 60 years, caused by inhalation of asbestos fibers, that continues to represent a social and healthcare…
Read MoreAsbestos Air Pollution: Description of a Mesothelioma Cluster Due to Residential Exposure from an Asbestos Cement Factory.
International Journal of Environmental Research and Public Health 2020 April 12 [Link] Vimercati L, Cavone D, Delfino MC, Caputi A, De Maria L, Sponselli S, Corrado V, Ferri GM, Serio G Abstract The study describes a cluster of 71 malignant mesothelioma cases among Bari residents without asbestos exposure other than residential exposure. This small cohort,…
Read MoreAssociation between asbestos exposure and pericardial and tunica vaginalis testis malignant mesothelioma: a case-control study and epidemiological remarks.
Scandinavian Journal of Work and Environmental Health 2020 April 7 [Link] Marinaccio A, Consonni D, Mensi C, Mirabelli D, Migliore E, Magnani C, Di Marzio D, Gennaro V, Mazzoleni G, Girardi P, Negro C, Romanelli A, Chellini E, Grappasonni I, Madeo G, Romeo E, Ascoli V, Carrozza F, Angelillo IF, Cavone D, Tumino R, Melis…
Read MoreMeasurement of asbestos emissions associated with demolition of abandoned residential dwellings.
The Science of the Total Environment 2020 March 21 [Link] Neitzel RL, Sayler SK, Demond AH, d’Arcy H, Garabrant DH, Franzblau A Abstract Many cities are revitalizing their urban cores through the demolition of abandoned residential dwellings (ARDs). However, data regarding the emissions of asbestos during such an operation are sparse. We measured airborne asbestos…
Read More