Occupational Asbestos Exposure
Current Status of Staging and Restaging Malignant Pleural Mesothelioma
Seminars in Nuclear Medicine 2025 March [Link] Egesta Lopci Malignant pleural mesothelioma (MPM) is the most frequent aggressive tumor affecting the pleura, accounting for over 38,000 deaths worldwide. It originates from the mesothelial cells and is mostly associated to asbestos exposure. Depending on the extent of the disease, the management of MPM varies from surgical…
Read MoreHuman Exposure to Asbestos in Central Asian Countries and Health Effects: A Narrative Review
La Medicina del lavoro 2024 December 19 [Link] Zhyldyz Kurzhunbaeva, Kenesh Dzhusupov, Andrea Spinazzè, Silvia Damiana Visonà, Cholpon Sulaimanova, Omor Kasymov, Elena Belluso, Claudio Colosio Abstract The discovery of the detrimental effects of asbestos on human health came long after its widespread use, with the first scientific evidence of asbestos-related diseases emerging in the late…
Read MoreClinical Perspectives and Novel Preclinical Models of Malignant Pleural Mesothelioma: A Critical Review
ACS Pharmacology and Translational Science 2024 October 14 [Link] Aliakbar Ebrahimi, Güntülü Ak, Ceren Özel, Hüseyin İzgördü, Hamed Ghorbanpoor, Shabir Hassan, Huseyin Avci, Muzaffer Metintaş Abstract Pleural mesothelioma (PM), a rare malignant tumor explicitly associated with asbestos and erionite exposures, has become a global health problem due to limited treatment options and a poor prognosis,…
Read MoreCase report: targeted therapy of malignant pleural mesothelioma with anaplastic lymphoma kinase receptor tyrosine kinase gene fusion mutation by crizotinib
The Journal of Medical Research 2024 November [Link] Yufeng Wu, Yuhua Zhao, Limeng Yu, Ruilin Wang, Wen Feng, Yingxi Wu, Lili Wang, Haiyang Chen, Zhen He, Qiming Wang Abstract Malignant mesothelioma is a rare highly invasive tumour originating from the mesothelial cells of the pleura, peritoneum and pericardium. Malignant pleural mesothelioma (MPM) is the most…
Read MoreAscites as a Rare Manifestation of Malignant Peritoneal Mesothelioma: A Case Report
Cureus 2024 October 7 [Link] Sean Lief, Srihita Patibandla, Ali Z Ansari, Nilay Bhatt, Azouba Gulraiz, Samer M Beauti, Rashad Ali Abstract Malignant peritoneal mesothelioma (MPM) is an aggressive neoplasm that originates from the mesothelial cells lining the parietal peritoneum or visceral peritoneum and extensively spreads within the abdominal cavity. It is a rare malignancy…
Read MoreMetastatic Mesothelioma of the Tunica Vaginalis Presenting as Scrotal and Abdominal Nodules: A Case Report and Review of the Literature
The American Journal of Dermatopathology 2025 January 1 [Link] Aubre Gilbert, Rebekah Wieland, Natasha Zacher, Kerri Rieger, Gerald J Berry, Roberto Novoa Abstract Mesothelioma of the tunica vaginalis testis (MMTVT) is a rare neoplasm comprising <3% of all cases of malignant mesothelioma (MM). MMTVT derives from the tunica vaginalis testis, an outpouching of the mesothelial-lined…
Read MoreActivation of platelet-derived growth factor receptors regulate connective tissue growth factor protein levels via the AKT pathway in malignant mesothelioma cells
Journal of Biochemistry 2024 December 2 [Link] Tomoya Suehiro, Khoja Mouhand Ahmad, Nguyen Truong Duc Hoang, Bingwen Xu, Honoka Komatsu, Komei Kurachi, Hiroki Nikawa, Yuichi Mine, Tohru Matsuki, Katsura Asano, Makiko Fujii Abstract The incidence of malignant mesothelioma (MM), a disease linked to refractory asbestos exposure, continues to increase globally and remains largely resistant to…
Read MoreA gut microbiota rheostat forecasts responsiveness to PD-L1 and VEGF blockade in mesothelioma
Nature Communications 2024 August 21 [Link] Min Zhang, Aleksandra Bzura, Essa Y Baitei, Zisen Zhou, Jake B Spicer, Charlotte Poile, Jan Rogel, Amy Branson, Amy King, Shaun Barber, Tamihiro Kamata, Joanna Dzialo, James Harber, Alastair Greystoke, Nada Nusrat, Daniel Faulkner, Qianqian Sun, Luke Nolan, Jens C Hahne, Molly Scotland, Harriet Walter, Liz Darlison, Bruno Morgan,…
Read MorePrimary Peritoneal Mesothelioma Affecting the Greater Omentum That Mimicked an Omental Infarction: A Case Report
Case Reports in Oncology 2024 May 30 [Link] John Corbyn Cravero, Taylor Yakubik, Laith Wahab, Thao Giang, Lisa M Lopez, Megan G Newman Abstract Introduction: Malignant peritoneal mesothelioma (MPM) is a rare cancer that is associated with asbestos exposure. The diagnosis can be difficult given the nonspecific nature of presenting symptoms and the presence of…
Read MoreIncidental Diagnosis of Malignant Peritoneal Mesothelioma During Liver Transplantation Surgery: A Case Report
The American Journal of Case Reports 2024 July 17 [Link] Spogmai Khan, Adnan Malik, Shahbaz Qureshi, Babak Cohen, Abdul Nadir Abstract BACKGROUND Malignant peritoneal mesothelioma (MPM) is a rare, lethal tumor of serous membranes. The most common factor reported in association with MPM is asbestos exposure, while viral infections, genetic predisposition, paraneoplastic syndrome, and altered…
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