Treatment
Immune Checkpoint Inhibitor Uptake in Real-World Patients With Malignant Pleural Mesothelioma
JTO Clinical and Research Reports 2021 May 18 [Link] Roger Y Kim, Nandita Mitra, Stephen J Bagley, Melina E Marmarelis, Andrew R Haas, Katharine A Rendle, Anil Vachani Abstract Introduction: Since the July 2017 National Comprehensive Cancer Network (NCCN) malignant pleural mesothelioma (MPM) guideline revision recommended second-line immune checkpoint inhibitors (ICIs), studies have suggested a…
Read MoreInhibition of CDK4/6 Overcomes Primary Resistance to PD-1 Blockade in Malignant Mesothelioma
The Annals of Thoracic Surgery 2021 September 27 [Link] Hee-Jin Jang, Cynthia Y Truong, Eric M Lo, Hudson M Holmes, Daniela Ramos, Maheshwari Ramineni, Ju-Seog Lee, Daniel Y Wang, Massimo Pietropaolo, R Taylor Ripley, Bryan M Burt, Hyun-Sung Lee Abstract Background: Despite the profound number of malignant pleural mesothelioma (MPM) patients now treated with PD-1…
Read MoreHyperthermic Intrathoracic Chemotherapy (HITOC) after Cytoreductive Surgery for Pleural Malignancies-A Retrospective, Multicentre Study
Cancers 2021 September 12 [Link] Michael Ried, Julia Kovács, Till Markowiak, Karolina Müller, Gunnar Huppertz, Michael Koller, Hauke Winter, Laura V Klotz, Rudolf Hatz, Julia Zimmermann, Bernward Passlick, Severin Schmid, Mohamed Hassan, Martin E Eichhorn, Hans-Stefan Hofmann Abstract In the context of quality assurance, the objectives were to describe the surgical treatment and postoperative morbidity…
Read MoreHyperthermic Intrathoracic Chemotherapy (HITOC) after Cytoreductive Surgery for Pleural Malignancies-A Retrospective, Multicentre Study
Cancers 2021 September 12 [Link] Michael Ried, Julia Kovács, Till Markowiak, Karolina Müller, Gunnar Huppertz, Michael Koller, Hauke Winter, Laura V Klotz, Rudolf Hatz, Julia Zimmermann, Bernward Passlick, Severin Schmid, Mohamed Hassan, Martin E Eichhorn, Hans-Stefan Hofmann Abstract In the context of quality assurance, the objectives were to describe the surgical treatment and postoperative morbidity…
Read MoreIntegrated genomics point to immune vulnerabilities in pleural mesothelioma
Scientific Reports 2021 September 27 [Link] Anca Nastase, Amit Mandal, Shir Kiong Lu, Hima Anbunathan, Deborah Morris-Rosendahl, Yu Zhi Zhang, Xiao-Ming Sun, Spyridon Gennatas, Robert C Rintoul, Matthew Edwards, Alex Bowman, Tatyana Chernova, Tim Benepal, Eric Lim, Anthony Newman Taylor, Andrew G Nicholson, Sanjay Popat, Anne E Willis, Marion MacFarlane, Mark Lathrop, Anne M Bowcock,…
Read MoreSurface-fill hydrogel attenuates the oncogenic signature of complex anatomical surface cancer in a single application
Nature Nanotechnology 2021 September 23 [Link] Poulami Majumder, Anand Singh, Ziqiu Wang, Kingshuk Dutta, Roma Pahwa, Chen Liang, Caroline Andrews, Nimit L Patel, Junfeng Shi, Natalia de Val, Scott T R Walsh, Albert Byungyun Jeon, Baktiar Karim, Chuong D Hoang, Joel P Schneider Abstract Tumours growing in a sheet-like manner on the surface of organs…
Read MoreGOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma
World Journal of Clinical Oncology 2021 August 24 [Link] Javier Luna, Andrea Bobo, Joaquín José Cabrera-Rodriguez, María Pagola, Margarita Martín-Martín, María Ángeles González Ruiz, Miguel Montijano, Aurora Rodríguez, Lira Pelari-Mici, Almudena Corbacho, Marta Moreno, Felipe Couñago Abstract Malignant pleural mesothelioma (MPM) is a rare tumor with poor prognosis and rising incidence. Palliative care is common…
Read MoreGOECP/SEOR clinical guidelines on radiotherapy for malignant pleural mesothelioma
World Journal of Clinical Oncology 2021 August 24 [Link] Javier Luna, Andrea Bobo, Joaquín José Cabrera-Rodriguez, María Pagola, Margarita Martín-Martín, María Ángeles González Ruiz, Miguel Montijano, Aurora Rodríguez, Lira Pelari-Mici, Almudena Corbacho, Marta Moreno, Felipe Couñago Abstract Malignant pleural mesothelioma (MPM) is a rare tumor with poor prognosis and rising incidence. Palliative care is common…
Read MoreHyperthermic Intrathoracic Chemotherapy for Malignant Pleural Mesothelioma: The Forefront of Surgery-Based Multimodality Treatment
Journal of Clinical Medicine 2021 August 25 [Link] Vittorio Aprile, Alessandra Lenzini, Filippo Lococo, Diana Bacchin, Stylianos Korasidis, Maria Giovanna Mastromarino, Giovanni Guglielmi, Gerardo Palmiero, Marcello Carlo Ambrogi, Marco Lucchi Abstract Introduction: Malignant Pleural Mesothelioma (MPM) is characterized by an aggressive behavior and an inevitably fatal prognosis, whose treatment is still far from being standardized.…
Read MoreGemcitabine with or without ramucirumab as second-line treatment for malignant pleural mesothelioma (RAMES): a randomised, double-blind, placebo-controlled, phase 2 trial
The Lancet Oncology 2021 September 6 [Link] Carmine Pinto, Paolo Andrea Zucali, Maria Pagano, Federica Grosso, Giulia Pasello, Marina Chiara Garassino, Marcello Tiseo, Hector Soto Parra, Francesco Grossi, Federico Cappuzzo, Filippo de Marinis, Paolo Pedrazzoli, Maria Bonomi, Letizia Gianoncelli, Matteo Perrino, Armando Santoro, Francesca Zanelli, Candida Bonelli, Antonio Maconi, Stefano Frega, Erika Gervasi, Luca Boni,…
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