MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Metformin and survival of people with type 2 diabetes and pleural mesothelioma: A population-based retrospective cohort study

Similar non-statistically significant associations were obtained in sensitivity analyses based on metformin use in year prior to diagnosis of mesothelioma, use of metformin for more than one year, in people below the mean age at diagnosis of mesothelioma (74 years) and 74 years of age or older, limitation to pleural mesothelioma and following further adjustment for body mass index and smoking. CONCLUSION: There was no evidence that metformin improved survival among people with type 2 diabetes and pleural mesothelioma or to support trials of metformin in people with mesothelioma.
Comments Off on Metformin and survival of people with type 2 diabetes and pleural mesothelioma: A population-based retrospective cohort study

The Role of 18F-FDG PET/CT Integrated Imaging in Distinguishing Malignant from Benign Pleural Effusion

CONCLUSION: 18F-FDG PET/CT integrated imaging is a more reliable modality in distinguishing malignant from benign pleural effusion than 18F-FDG PET imaging and CT imaging alone. For image interpretation of 18F-FDG PET/CT integrated imaging, the PET and CT portions play a major diagnostic role in identifying metastatic effusion and benign effusion, respectively.
Comments Off on The Role of 18F-FDG PET/CT Integrated Imaging in Distinguishing Malignant from Benign Pleural Effusion

Asbestos exposure and histological subtype of malignant mesothelioma

Other indicators of asbestos exposure were not associated with the histological subtype of mesothelioma. CONCLUSIONS: There was no strong evidence of a consistent role of asbestos exposure indicators in determining the histological subtype of MM.
Comments Off on Asbestos exposure and histological subtype of malignant mesothelioma

Symptom Burden in mesothelioma patients admitted to home palliative care

The principal pain site was the chest. Pain was significantly associated with opioid consumption (p .
Comments Off on Symptom Burden in mesothelioma patients admitted to home palliative care

Pembrolizumab-associated minimal change disease in a patient with malignant pleural mesothelioma

CONCLUSION: We are the first to describe pembrolizumab-related minimal change disease (MCD). Physicians should be aware of this side effect in patients presenting with edema and weight gain and initiate prompt renal function testing, serum albumin and urinalysis followed by steroid treatment if pembrolizumab-related MCD is suspected.
Comments Off on Pembrolizumab-associated minimal change disease in a patient with malignant pleural mesothelioma

o-existing tuberculosis and malignant mesothelioma with multiple sites venous thrombosis: a case report

Later on computed tomography peritoneal nodule was detected and on biopsy revealed malignant mesothelioma. CONCLUSION: In a diagnosed case of tuberculosis with clinical findings compatible with it but not responding to anti tubercular therapy, underlying secondary co-existing pathology should be explored.
Comments Off on o-existing tuberculosis and malignant mesothelioma with multiple sites venous thrombosis: a case report

What is Mesothelioma?

Learn more about this fatal cancer, including the causes, symptoms, and treatments for both pleural and peritoneal tumors of the mesothelium at our parent site MesotheliomaCenter.

Comparison of SKIP expression in malignant pleural mesotheliomas with Ki-67 proliferation index and prognostic parameters

Cox regression analysis revealed that high SKIP expression, high Ki-67 proliferative index and presence of non-epithelioid type MPM are independent factors that affect the survival rate. Higher SKIP expression is associated with poor prognosis in MPM.
Comments Off on Comparison of SKIP expression in malignant pleural mesotheliomas with Ki-67 proliferation index and prognostic parameters

Malignant mesothelioma effusions are infiltrated by CD3+ T cells highly expressing PD-L1 and the PD-L1+ tumor cells within these effusions are susceptible to ADCC by the anti-PD-L1 antibody avelumab

Malignant effusions in this disease are characterized by presence of tumor cells and CD3+ T cells that highly express PD-L1. In addition, mesothelioma tumor cells are susceptible to ADCC by anti-PD-L1 antibody avelumab.
Comments Off on Malignant mesothelioma effusions are infiltrated by CD3+ T cells highly expressing PD-L1 and the PD-L1+ tumor cells within these effusions are susceptible to ADCC by the anti-PD-L1 antibody avelumab

Alveolar-filling growth pattern of sarcomatoid malignant pleural mesothelioma

Histopathologically, the sarcomatoid spindle tumour cells changed their morphology to polygonal cells in the pulmonary parenchyma and grew upwards, filling the alveolar space without the destruction of its septa, showing an alveolar-filling growth pattern. The current report indicates a case of sarcomatoid pleural mesothelioma that shows an alveolar-filling growth pattern, despite having not been thoroughly categorized in the World Health Organization (WHO) classification.
Comments Off on Alveolar-filling growth pattern of sarcomatoid malignant pleural mesothelioma

Symptom Burden in mesothelioma patients admitted to home palliative care

The principal pain site was the chest. Pain was significantly associated with opioid consumption (p .
Comments Off on Symptom Burden in mesothelioma patients admitted to home palliative care