MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Isolated thoracic perfusion with chemofiltration for progressive malignant pleural mesothelioma

Median overall survival was 12 months and progression-free survival 9 months. CONCLUSION: ITP-F for patients with advanced pleural mesothelioma, progressive after standard therapies, is an effective and well-tolerated treatment modality, offering comparably long survival data at a good QoL.
Comments Off on Isolated thoracic perfusion with chemofiltration for progressive malignant pleural mesothelioma

Epithelioid Malignant Mesothelioma Metastatic to the Skin: A Case Report and Review of the Literature

. Journal of Cutaneous Pathology 2017 August [Epub ahead of print] [Link] Ward RE, Ali SA, Kuhar M Abstract Mesothelioma is a rare form of cancer arising from a monolayer of mesothelial cells that form the lining of the internal body cavities and organs, with the vast majority of cases arising from the pleura (65-80%), less commonly from the peritoneum (10-30%), and rarely from the pericardium and tunica vaginalis testis (1-2%).
Comments Off on Epithelioid Malignant Mesothelioma Metastatic to the Skin: A Case Report and Review of the Literature

Malignant Pleural Mesothelioma: State of the art and advanced cell therapy

Alternative strategies to the commonly used combination-therapy resulted from the use of Mesenchymal Stromal Cells (MSC) widely used in the field of regenerative medicine and recently proposed as natural carriers for a selective delivery of chemotherapeutic agents and from the use of immune checkpoint and kinase inhibitors. The present short review shed light on the recent state of art and the future perspectives relative to MPM therapy.
Comments Off on Malignant Pleural Mesothelioma: State of the art and advanced cell therapy

Isolated thoracic perfusion with chemofiltration for progressive malignant pleural mesothelioma

Median overall survival was 12 months and progression-free survival 9 months. CONCLUSION: ITP-F for patients with advanced pleural mesothelioma, progressive after standard therapies, is an effective and well-tolerated treatment modality, offering comparably long survival data at a good QoL.
Comments Off on Isolated thoracic perfusion with chemofiltration for progressive malignant pleural mesothelioma

Malignant pleural mesothelioma segmentation for photodynamic therapy planning

79 and we obtained a value of 0. 88 using the Dice index.
Comments Off on Malignant pleural mesothelioma segmentation for photodynamic therapy planning

MicroRNA Expression in Malignant Pleural Mesothelioma and Asbestosis: A Pilot Study

CONCLUSIONS: All the miRNA levels were decreased in patients with MPM or ASB, supporting the role of circulating miRNAs as a potential tool for diseases associated with exposure to asbestos fibers. miRNA-16 was directly related to MPM patient prognosis, suggesting its possible use as a prognostic marker in MPM patients.
Comments Off on MicroRNA Expression in Malignant Pleural Mesothelioma and Asbestosis: A Pilot Study

What is Mesothelioma?

Learn more about this fatal cancer, including the causes, symptoms, and treatments for both pleural and peritoneal tumors of the mesothelium at our parent site MesotheliomaCenter.

Indolent peritoneal mesothelioma: PI3K-mTOR inhibitors as a novel therapeutic strategy

This series identifies the use of targeted therapies with PI3K-mTOR-based inhibitors as a novel approach, warranting further clinical assessment. Development of prognostic biomarkers is essential to aid identify tumour aggressiveness, help stratify patients and facilitate treatment decisions.
Comments Off on Indolent peritoneal mesothelioma: PI3K-mTOR inhibitors as a novel therapeutic strategy

Italian pool of asbestos workers cohorts: mortality trends of asbestos-related neoplasms after long time since first exposure

DISCUSSION: The study confirmed the increased risk for cancer of the lung, ovary, pleura and peritoneum but not of the larynx and the digestive tract. Pleural cancer mortality reached a plateau at long TSFE, coherently with recent reports.
Comments Off on Italian pool of asbestos workers cohorts: mortality trends of asbestos-related neoplasms after long time since first exposure

Diagnostic value of medical thoracoscopy in malignant pleural effusion

No serious adverse events associated with thoracoscopy were recorded. CONCLUSIONS: Medical thoracoscopy is a valuable and safe tool in diagnosing malignant pleural effusion with minimal complication rates.
Comments Off on Diagnostic value of medical thoracoscopy in malignant pleural effusion

The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: Evidence-Based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center.

Criteria for the interpretation of various other combinations of immunoreactivity for cytokeratin, mesothelial and/or epithelial markers are proposed. Localized sarcomatoid mesotheliomas can only be diagnosed in the presence of spindle cell malignancies that exhibit immunoreactivity for cytokeratin and mesothelial markers and negative immunoreactivity for epithelial lesions, in patients that show no multifocal or diffuse pleural spread and no evidence for extrapleural lesions.
Comments Off on The differential diagnosis between pleural sarcomatoid mesothelioma and spindle cell/pleomorphic (sarcomatoid) carcinomas of the lung: Evidence-Based guidelines from the International Mesothelioma Panel and the MESOPATH National Reference Center.