Pharmacological inhibition of CDK4/6 impairs diffuse pleural mesothelioma 3D spheroid growth and reduces viability of cisplatin-resistant cells

July 22, 2024 | Comments Off on Pharmacological inhibition of CDK4/6 impairs diffuse pleural mesothelioma 3D spheroid growth and reduces viability of cisplatin-resistant cells

Frontiers in Oncology 2024 July 1 [Link] Aurora Costa, Iris Maria Forte, Francesca Pentimalli, Carmelina Antonella Iannuzzi, Luigi Alfano, Francesca Capone, Rosa Camerlingo, Alessandra Calabrese, Claudia von Arx, Reyes Benot…

A Rare Case of Pleural Epithelioid Mesothelioma With a Prominent Myxoid Stroma Reported With Morphology, Fluorescent In Situ Hybridization, and Ultrastructural Findings

July 19, 2024 | Comments Off on A Rare Case of Pleural Epithelioid Mesothelioma With a Prominent Myxoid Stroma Reported With Morphology, Fluorescent In Situ Hybridization, and Ultrastructural Findings

Cureus 2024 June 12 [Link] Hiroshi Sonobe, Rika Omote, Toshiyuki Habara, Kazuhiro Washio, Nobuyoshi Yamazoe, Shinji Matsumoto, Kazuki Nabeshima, Hiroko Toda Abstract Herein, we report a rare case of pleural…

Germline BARD1 variants predispose to mesothelioma by impairing DNA repair and calcium signaling

July 18, 2024 | Comments Off on Germline BARD1 variants predispose to mesothelioma by impairing DNA repair and calcium signaling

Proceedings of the National Academy of Sciences of the United States of America 2024 July 16 [Link] Flavia Novelli, Yoshie Yoshikawa, Veronica Angela Maria Vitto, Lorenzo Modesti, Michael Minaai, Sandra…

Characterizing soluble immune checkpoint molecules and TGF-β1,2,3 in pleural effusion of malignant pleural mesothelioma

July 17, 2024 | Comments Off on Characterizing soluble immune checkpoint molecules and TGF-β1,2,3 in pleural effusion of malignant pleural mesothelioma

Scientific Reports 2024 July 10 [Link] Riki Okita, Tomoya Senoo, Yuka Mimura-Kimura, Yusuke Mimura, Tomoyuki Murakami, Eiji Ikeda, Masanori Okada, Hidetoshi Inokawa, Keisuke Aoe Abstract The clinical impact of soluble…

A rare case of a huge malignant pleural mesothelioma presenting in the posterior mediastinum

July 16, 2024 | Comments Off on A rare case of a huge malignant pleural mesothelioma presenting in the posterior mediastinum

Respirology Case Reports 2024 July 9 [Link] Yuta Mori, Chihiro Kato, Hideo Yamakawa, Mariko Sugiura, Kensuke Fukumitsu, Satoshi Fukuda, Yoshihiro Kanemitsu, Takehiro Uemura, Tomoko Tajiri, Hirotsugu Ohkubo, Yutaka Ito, Tetsuya…

Major pathological response obtained after neoadjuvant chemotherapy combined with dual immunotherapy for malignant pleural mesothelioma: a case report

July 15, 2024 | Comments Off on Major pathological response obtained after neoadjuvant chemotherapy combined with dual immunotherapy for malignant pleural mesothelioma: a case report

Translational Lung Cancer Research 2024 June 30 [Link] Yuchen Zhang, Guangyin Zhao, Chen Xu, Jie Gu, Di Ge Abstract Background: Malignant pleural mesothelioma (MPM) is a rare thoracic malignancy with…

Real-World efficacy and safety of combination nivolumab plus ipilimumab for Untreated, Unresectable, pleural Mesothelioma: The Meso-Immune (GFPC 04-2021) trial

July 11, 2024 | Comments Off on Real-World efficacy and safety of combination nivolumab plus ipilimumab for Untreated, Unresectable, pleural Mesothelioma: The Meso-Immune (GFPC 04-2021) trial

Lung Cancer 2024 June 29 [Link] Olivier Bylicki, Florian Guisier, Arnaud Scherpereel, Catherine Daniel, Aurélie Swalduz, Emmanuel Grolleau, Marie Bernardi, Stephane Hominal, Jean Briac Prevost, Guillaume Pamart, Marie Héléne Marques,…

Single cell view of tumor microenvironment gradients in pleural mesothelioma

July 10, 2024 | Comments Off on Single cell view of tumor microenvironment gradients in pleural mesothelioma

Cancer Discovery 2024 July 5 [Link] Bruno Giotti, Komal Dolasia, William Zhao, Peiwen Cai, Robert Sweeney, Elliot Merritt, Evgeny Kiner, Grace S Kim, Atharva Bhagwat, Thinh Nguyen, Samarth Hegde, Bailey…

Fibroblast Activation Protein-Directed Imaging Outperforms 18F-FDG PET/CT in Malignant Mesothelioma: A Prospective, Single-Center, Observational Trial

July 9, 2024 | Comments Off on Fibroblast Activation Protein-Directed Imaging Outperforms 18F-FDG PET/CT in Malignant Mesothelioma: A Prospective, Single-Center, Observational Trial

Journal of Nuclear Medicine 2024 July 3 [Link] Lukas Kessler, Felix Schwaning, Martin Metzenmacher, Kim Pabst, Jens Siveke, Marija Trajkovic-Arsic, Benedikt Schaarschmidt, Marcel Wiesweg, Clemens Aigner, Till Plönes, Kaid Darwiche,…

Thonzonium bromide inhibits progression of malignant pleural mesothelioma through regulation of ERK1/2 and p38 pathways and mitochondrial uncoupling

July 8, 2024 | Comments Off on Thonzonium bromide inhibits progression of malignant pleural mesothelioma through regulation of ERK1/2 and p38 pathways and mitochondrial uncoupling

Cancer Cell International 2024 June 29 [Link] Irene Dell’Anno, Federica Morani, Simone Patergnani, Antonio Daga, Paolo Pinton, Carlotta Giorgi, Luciano Mutti, Federica Gemignani, Stefano Landi Abstract Background: Malignant Pleural Mesothelioma…

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