Telomeres and telomerase in mesothelioma: Pathophysiology, biomarkers and emerging therapeutic strategies (Review)

April 21, 2025 | Comments Off on Telomeres and telomerase in mesothelioma: Pathophysiology, biomarkers and emerging therapeutic strategies (Review)

International Journal of Oncology 2025 March [Link] Dimitrios Andreikos, Demetrios A Spandidos, Vasiliki Epameinondas Georgakopoulou Abstract Malignant mesothelioma (MM) is a rare but aggressive cancer linked to asbestos exposure and…

miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma

April 18, 2025 | Comments Off on miRNA-503 inhibition exerts anticancer effects and reduces tumor growth in mesothelioma

Journal of Experimental & Clinical Cancer Research 2025 February 22 [Link] Miriam Piccioni, Francesco Di Meo, Anna Valentino, Virginia Campani, Maddalena Arigoni, Mirella Tanori, Mariateresa Mancuso, Rossana Cuciniello, Marco Tomasetti,…

The phenogenomic landscapes of pleural mesothelioma tumor microenvironment predict clinical outcomes

April 17, 2025 | Comments Off on The phenogenomic landscapes of pleural mesothelioma tumor microenvironment predict clinical outcomes

Journal of Translational Medicine 2025 February 20 [Link] Federica Torricelli, Filomena Spada, Cynthia Bishop, Katrina Todd, Daisuke Nonaka, Nedyalko Petrov, Manuela Terranova Barberio, Alan G Ramsay, Richard Ellis, Alessia Ciarrocchi,…

CD276 as a critical independent biomarker and immune checkpoint inhibitor target in epithelioid mesothelioma-TCGA study

April 16, 2025 | Comments Off on CD276 as a critical independent biomarker and immune checkpoint inhibitor target in epithelioid mesothelioma-TCGA study

Journal of Thoracic Disease 2025 January 24 [Link] Yuko Aoki, Ken Arimura, Kenzo Hiroshima, Yasuto Sato, Mitsuko Kondo, Etsuko Tagaya Abstract Background: CD276 is an immune checkpoint, and immune checkpoint…

DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy

April 15, 2025 | Comments Off on DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy

Journal of Experimental & Clinical Cancer Research 2025 February 18 [Link] Maria Fortunata Lofiego, Rossella Tufano, Emma Bello, Laura Solmonese, Francesco Marzani, Francesca Piazzini, Fabrizio Celesti, Francesca Pia Caruso, Teresa…

Potential utility of miRNAs derived from pleural fluid extracellular vesicles to differentiate between benign and malignant pleural effusions

April 14, 2025 | Comments Off on Potential utility of miRNAs derived from pleural fluid extracellular vesicles to differentiate between benign and malignant pleural effusions

Translational Lung Cancer Research 2025 January 24 [Link] Tian Mun Chee, Caeli J Zahra, Kwun M Fong, Ian A Yang, Rayleen V Bowman Abstract Background: Cytological examination is of suboptimal…

Prognostic importance of the neutrophil-to-lymphocyte ratio in malignant peritoneal mesothelioma patients receiving cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

April 11, 2025 | Comments Off on Prognostic importance of the neutrophil-to-lymphocyte ratio in malignant peritoneal mesothelioma patients receiving cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

BMC Cancer 2025 February 14 [Link] Zhang Xinjing, Gong Lei, Li Xinbao, Ji Zhonghe, Yang Zhiran, Gao Chao, Zhang Kai, Yan Lijun, Yan Guojun, Yu Junhui, Zhang Yanbin, An Songlin…

Prognostic Stratification of Epithelioid Pleural Mesothelioma Based on the Hippo-TEADs Network

April 10, 2025 | Comments Off on Prognostic Stratification of Epithelioid Pleural Mesothelioma Based on the Hippo-TEADs Network

Cancers 2025 January 30 [Link] Anello Marcello Poma, Rossella Bruno, Iacopo Petrini, Iosè Di Stefano, Alessandra Celi, Andrea Sbrana, Sabrina Cappelli, Antonio Chella, Franca Melfi, Marco Lucchi, Greta Alì Abstract…

Diagnostic Challenges in the Pathological Approach to Pleural Mesothelioma

April 9, 2025 | Comments Off on Diagnostic Challenges in the Pathological Approach to Pleural Mesothelioma

Cancers 2025 February 1 [Link] Stefano Lucà, Giovanna Pignata, Alessandro Cioce, Cecilia Salzillo, Rossella De Cecio, Gerardo Ferrara, Carminia Maria Della Corte, Floriana Morgillo, Alfonso Fiorelli, Marco Montella, Renato Franco…

A Meta-Analysis of First-Line Treatments for Unresectable Pleural Mesothelioma: Indirect Comparisons from Reconstructed Individual Patient Data of Six Randomized Controlled Trials

April 8, 2025 | Comments Off on A Meta-Analysis of First-Line Treatments for Unresectable Pleural Mesothelioma: Indirect Comparisons from Reconstructed Individual Patient Data of Six Randomized Controlled Trials

Cancers 2025 February 3 [Link] Andrea Messori, Sabrina Trippoli, Eugenia Piragine, Sara Veneziano, Vincenzo Calderone Abstract Background: In unresectable pleural mesothelioma, pemetrexed+cisplatin as first line is considered the standard of…

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