Ad-SGE-DKK3 Gene Therapy Overcomes Resistance to Immune Checkpoint Blockade in Pleural Mesothelioma

May 23, 2025 | Comments Off on Ad-SGE-DKK3 Gene Therapy Overcomes Resistance to Immune Checkpoint Blockade in Pleural Mesothelioma

Clinical Cancer Research 2025 April 10 [Link] Hee-Jin Jang, Meera Patel, Daniel Y Wang, Sung Wook Kang, Jong Min Choi, Claire Lee, Monica Vilchis, Ji Seon Shim, Sonali Mitra, Priyanka…

Cytoplasmic HuR Expression Enhances Chemoresistance in Pleural Mesothelioma Through Increased Expression of CALB2, Promotion of the E2F Pathway, and Suppression of the p53 Pathway

May 22, 2025 | Comments Off on Cytoplasmic HuR Expression Enhances Chemoresistance in Pleural Mesothelioma Through Increased Expression of CALB2, Promotion of the E2F Pathway, and Suppression of the p53 Pathway

Thoracic Cancer 2025 April [Link] Susumu Kirimura, Morito Kurata, Hironori Ishibashi, Yusuke Taniguchi, Yuko Kinowaki, Keisuke Sugita, Kenichi Okubo Abstract Introduction: Chemotherapy is crucial for treating pleural mesothelioma; however, the…

Hyperthermic intrathoracic chemotherapy in patients with malignant pleural mesothelioma after cytoreductive surgical procedures: a systematic review

May 21, 2025 | Comments Off on Hyperthermic intrathoracic chemotherapy in patients with malignant pleural mesothelioma after cytoreductive surgical procedures: a systematic review

World Journal of Surgical Oncology 2025 April 9 [Link] Hany Hasan Elsayed, Mohamed Elanany Elsaid Elanany, Mohamed Tarek ElSayegh, Aly Sherif Hassaballa, Mohammed Abdel-Gayed Abstract Surgery-based multimodality therapies for treatment…

Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma

May 20, 2025 | Comments Off on Genome-wide CRISPR screen identifies BUB1 kinase as a druggable vulnerability in malignant pleural mesothelioma

Cell Death & Disease 2025 April 3 [Link] Ece Cakiroglu, Sude Eris, Ozden Oz, Gökhan Karakülah, Serif Senturk Abstract Malignant pleural mesothelioma (MPM) is a rare yet highly aggressive malignancy…

Utility and limitations of Merlin immunohistochemistry for mesothelioma diagnosis in tissue sections and cell blocks

May 19, 2025 | Comments Off on Utility and limitations of Merlin immunohistochemistry for mesothelioma diagnosis in tissue sections and cell blocks

Annals of Diagnostic Pathology 2025 August [Link] Kazuki Nabeshima, Makoto Hamasaki, Tomomi Furukawa, Shinji Matsumoto, Katsumi Takizawa, Makiko Adachi, Yuko Goto Abstract Distinguishing pleural mesothelioma (PM) from reactive mesothelial proliferations…

Diagnostic utility of pleuroscopic guided pleural biopsy versus pleural fluid cell block in the diagnosis of malignant pleural effusion

May 16, 2025 | Comments Off on Diagnostic utility of pleuroscopic guided pleural biopsy versus pleural fluid cell block in the diagnosis of malignant pleural effusion

The Medical Journal of Malaysia 2025 March [Link] B H Ng, H J Low, N N N Abeed, C I Soo, M I Azmi, N S Sharil, R A Osman,…

Ex-Vivo Drug-Sensitivity Testing to Predict Clinical Response in Non-Small Cell Lung Cancer and Pleural Mesothelioma: A Systematic Review and Narrative Synthesis

May 15, 2025 | Comments Off on Ex-Vivo Drug-Sensitivity Testing to Predict Clinical Response in Non-Small Cell Lung Cancer and Pleural Mesothelioma: A Systematic Review and Narrative Synthesis

Cancers 2025 March 14 [Link] Jenny Zipprick, Enes Demir, Hanna Krynska, Sıla Köprülüoğlu, Katharina Strauß, Marcus Skribek, Rita Hutyra-Gram Ötvös, Annica K B Gad, Katalin Dobra Abstract Background/objectives: Non-small cell…

DNA methylation-regulated HLA-C expression modulates immune responses and metabolic alterations to influence prognosis in mesothelioma

May 14, 2025 | Comments Off on DNA methylation-regulated HLA-C expression modulates immune responses and metabolic alterations to influence prognosis in mesothelioma

Cancer Immunology, Immunotherapy 2025 March 25 [Link] Huilin Zhang, Luanxue Yu, Yunqing Guo, Jiawei Ming, Zhenying Guo Abstract Background: Malignant mesothelioma is a highly aggressive cancer with a poor prognosis…

A woman with a pleural mesothelioma and an inherited ATM mutation-a case report

May 13, 2025 | Comments Off on A woman with a pleural mesothelioma and an inherited ATM mutation-a case report

Annals of Translational Medicine 2025 February 28 [Link] Marta Seca, B C John Cho, Angelina Tryon, Steven A Narod Abstract Background: Pleural mesothelioma (PM) is a rare and aggressive malignancy…

New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma

May 12, 2025 | Comments Off on New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma

Journal for Immunotherapy of Cancer 2025 March 17 [Link] Noémie Joalland, Agnès Quéméner, Sophie Deshayes, Romain Humeau, Mike Maillasson, Héloïse LeBihan, Apolline Salama, Judith Fresquet, Séverine Remy, Erwan Mortier, Christophe…

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