Pediatric Blood & Cancer. 2009 Jan;52(1):127-9. [Link]

Cioffredi LA, Jänne PA, Jackman DM.

Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.


Peritoneal mesothelioma is a rare and often aggressive malignancy, mostly affecting asbestos exposed adults. We present four pediatric peritoneal cases treated with a cisplatin-based doublet regimen, the standard of care in the systemic therapy of adult mesothelioma. Treatment was well tolerated, and three of these patients have achieved long-term survival. The fathers of three of the patients worked in the construction industry and may have been the source of indirect asbestos exposure.

Keywords: chemotherapy, pediatric oncology, solid tumors