The MARS trial: mesothelioma and radical surgery

Interactive Cardiovascular and Thoracic Surgery. 2006 Feb;5(1):58-9. Epub 2005 Nov 23. [Link]

Treasure T, Tan C, Lang-Lazdunski L, Waller D.

Thoracic Unit, Guy’s Hospital, SE1 9RT, London, UK.


The increasing incidence of malignant pleural mesothelioma has demanded the attention of thoracic surgeons worldwide. Can radical surgery cure mesothelioma or add usefully to the length and quality of life for its victims? The MARS (mesothelioma and radical surgery) trial is open and recruiting in Britain. If the trial proves feasible we will seek to make an international study.

Keywords: Malignant (pleural) mesothelioma; Extrapleural pneumonectomy; Randomized controlled trial; Trimodality cancer treatment