Prolonged survival due to spontaneous regression and surgical excision of malignant mesothelioma

The Annals of Thoracic Surgery. Volume 83, Issue 1 , January 2007, Pages 314-315 [Link]

John E. Pilling MRCSa, Andrew G. Nicholson FRCPathb, Clive Harmer FRCPc and Peter Goldstraw FRCSa

aDepartment of Thoracic Surgery, London, United Kingdom
bDepartment of Pathology, Royal Brompton Hospital, London, United Kingdom
cDepartment of Oncology, Royal Marsden Hospital, London, United Kingdom


We report a case of malignant pleural mesothelioma with histologically proven spontaneous regression of pleural disease. During a 12-year follow-up there was a single recurrence, which was a lesion in the chest wall at 6 years that was surgically excised. A prominent host response to tumor was seen in both the primary tumor and the recurrence.