Exclusive intrapulmonary lepidic growth of a malignant pleural mesothelioma presenting with pneumothorax and involving the peritoneum

International Journal of Surgical Pathology. 2006 Jul;14(3):234-7. [Link]

Rossi G, Cavazza A, Turrini E, Costantini M, Casali C, Morandi U, Dallari R.

Sections of Pathologic Anatomy; Azienda Policlinico, Modena.


We report a rare case of malignant pleural mesothelioma presenting clinically with pneumothorax and histologically with an exclusiveintrapulmonary lepidic growth. Neither intrathoracic nodules nor pleural thickening were found. The patient subsequently experienced acute abdominal pain with peritonitis and intestinal occlusion by peritoneal mesothelioma. The morphologic clues leading to the correct diagnosis of mesothelioma with prominent intrapulmonary growth are briefly discussed.