Lung Cancer 2015 June 23 [Epub ahead of print] [Link]

Buikhuisen WA, Hiddinga BI, Baas P, van Meerbeeck JP.


After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression. We conducted a systematic review of the literature for the activity, effectiveness and toxicity of second line treatment. The results are presented according to the class of drugs: chemotherapy and targeted or biological agent.