Radical surgery for mesothelioma

Cancer/Radiothérapie. 2006 Aug 31; [Epub ahead of print] [Link]

P. Bonnettea

aService de chirurgie thoracique, hôpital Foch, 40, rue Worth, 92151 Suresnes, France


Good results obtained by the team from Boston increased the interest in pleuropneumonectomy for mesothelioma. Adjuvant high-dose hemithoracic radiation after surgical resection decreased the local recurrence rate from 35 to 13%. The high rate of peritoneal (26-31%), controlateral pleural and pericardial recurrences justify the routine practice of preoperative laparoscopy and controlateral thoracoscopy and a pleuropneumonectomy without pericardotomy and diaphragmatic resection. The diaphragm is lowered to facilitate radiotherapy. Chemotherapy may be performed postoperatively.