Solitary fibrous pleural tumor

The Journal of the American Osteopathic Association. 2008 Jun;108(6):307-9. [Link]

Jenkins LA, O-Yurvati AH.

OMS IV, 3500 Camp Davie Blvd, Fort Worth, TX 76107-2970, USA.


Solitary fibrous pleural tumors are rare masses of mesenchymal origin that may be mistaken for mesothelioma. A positive staining of vimentin, negative staining of cytoplasmic keratin, and expression of the CD34 antigen can confirm the presence of a solitary fibrous pleural tumor. Although most tumors of this type are benign, they possess a malignant potential and thus should be excised. We report a case of a 63-year-old man who had an inconclusive biopsy of a lung lesion 15 years ago. Further testing after excision revealed a solitary fibrous pleural tumor. A brief discussion of the clinical presentation and incidence of these tumors is included.