Mediastinal Tumors: a Clinicopathological Analysis

Asian Cardiovascular & Thoracic Annals. 2006;14:102-104. [Link]

Chandra P Shrivastava, MCh, Sanjeev Devgarha, MCh, Vikas Ahlawat, MCh

Department of Cardiothoracic & Vascular Surgery, SMS Medical College & Hospital, Jaipur, India

For reprint information contact: Chandra P Shrivastava, MCh Tel: 91 141 237 7329 Fax: 91 141 260 9988 Email: cps_sms@hotmail.com, H-16, Chitranjan Marg, C-Scheme, Jaipur (Raj.), India.

Abstract

Between January 1993 and June 2003, 106 patients underwent surgical treatment of a mediastinal mass. Ages ranged from 6 months to 62 years, with peak incidence in the third and fourth decade of life (56%). The male to female ratio was 1.9:1. The anterosuperior mediastinum was involved in 76 patients (72%), middle mediastinum in 13 (12%), and posterior mediastinum in 17 (16%). Myasthenia gravis was present in 27% of cases. Complete surgical excision was possible in 68% of patients. Histopathologically, 41 (39%) patients had thymic pathology, 31 (29%) had lymphoma, 14 (13%) had germ cell tumors, 12 (11%) had neurofibroma, 4 (4%) had ganglioneuroma, 2 (2%) had bronchogenic cyst, and 1 each had thymic cyst and mesothelioma. The overall mortality was 3.8%.