Future Oncology (London, England) 2016 September 21 [Epub ahead of print] [Link]

Spatola C, Militello C, Tocco A, Salamone V, Raffaele L, Migliore M, Pagana A, Milazzotto R, Chillura I, Pergolizzi S, Privitera G


The use of novel radiotherapy techniques is widely increasing, allowing clinicians to treat diseases that were previously difficult to treat with radiation therapy. Malignant pleural mesothelioma is a clear example of this clinical challenge. We describe our first experience with intensity-modulated radiotherapy technique which was used to treat a 73-year-old patient with multiple relapsing malignant pleural mesothelioma. Intensity-modulated radiation therapy has allowed to respect the QUANTEC (quantitative analyses of normal tissue effects in the clinic) dose constraints, patient has experienced a 14 months progression-free time, without relevant subacute or late lung toxicity.