MesotheliomaCenter's

Mesothelioma-Line

Curated Journal Articles on Mesothelioma

Category Archives: Full Archive

The full archive of mesothelioma-related journal articles. All articles belong to this category.

Role of Inflammation in the Malignant Transformation of Pleural Mesothelial Cells Induced by Multi-Walled Carbon Nanotubes

Nanotoxicology 2020 June 23 [Link] Xiaopei Huang, Yijun Tian, Wenjing Shi, Jikuai Chen, Lang Yan, Lijun Ren, Xiaofang Zhang, Jiangbo Zhu Abstract Multi-walled carbon nanotubes (MWCNTs) are one of the most widely used types of novel nano-fiber materials. The aim of this study was to establish an experimental system based on actual exposure dosage and […]

Comments Off on Role of Inflammation in the Malignant Transformation of Pleural Mesothelial Cells Induced by Multi-Walled Carbon Nanotubes

Impairments in Bowel Function, Social Function and Quality of Life After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Annals of Surgical Oncology 2020 January [Link] Zubair Bayat, Emily L Taylor, Danielle A Bischof, J Andrea McCart, Anand Govindarajan Abstract Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) can be associated with decreases in quality of life (QOL). Bowel-related QOL (BR-QOL) after CRS-HIPEC has not been previously studied. The objectives of the current study […]

Comments Off on Impairments in Bowel Function, Social Function and Quality of Life After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Cisplatin Plus Pemetrexed Therapy and Subsequent Immune Checkpoint Inhibitor Administration for Malignant Peritoneal Mesothelioma Without Pleural Lesions: Case Report

Medicine 2020 May 29 [Link] Hiroaki Ikushima, Toshio Sakatani, Sayaka Ohara, Hideyuki Takeshima, Hajime Horiuchi, Teppei Morikawa, Kazuhiro Usui Abstract Rationale: Malignant peritoneal mesothelioma is a rare tumor with a poor prognosis and has no recommended therapy after first-line pemetrexed and platinum-based chemotherapy. Moreover, effects of immune checkpoint inhibitors on peritoneal mesothelioma remains to be […]

Comments Off on Cisplatin Plus Pemetrexed Therapy and Subsequent Immune Checkpoint Inhibitor Administration for Malignant Peritoneal Mesothelioma Without Pleural Lesions: Case Report

Breast Metastasis as the Initial Presentation of Malignant Pleural Mesothelioma

The Breast Journal 2020 May 30 [Link] Lea Korša, Ana Lukač, Lucija Kovačević, Ivan Bilić, Maja Prutki, Zlatko Marušić Abstract Metastatic involvement of the breast is far less common than primary breast carcinoma, comprising 0.5%-6.6% of all breast malignancies. Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor with higher incidence among men, particularly […]

Comments Off on Breast Metastasis as the Initial Presentation of Malignant Pleural Mesothelioma

Amrubicin in Previously Treated Patients With Malignant Pleural Mesothelioma: A Phase II Study

Thoracic Cancer 2020 May 28 [Link] Takaya Ikeda, Shinnosuke Takemoto, Hiroaki Senju, Hiroshi Gyotoku, Hirokazu Taniguchi, Midori Shimada, Yosuke Dotsu, Yasuhiro Umeyama, Hiromi Tomono, Takeshi Kitazaki, Masaaki Fukuda, Hiroshi Soda, Hiroyuki Yamaguchi, Minoru Fukuda, Hiroshi Mukae Abstract Background: The aim of this study was to assess the efficacy and safety of amrubicin for previously treated […]

Comments Off on Amrubicin in Previously Treated Patients With Malignant Pleural Mesothelioma: A Phase II Study

Initial Evaluation of Nivolumab in Patients With Post-Operative Recurrence of Malignant Pleural Mesothelioma

Japanese Journal of Clinical Oncology 2020 May 28 [Link] Akifumi Nakamura, Nobuyuki Kondo, Toru Nakamichi, Ayumi Kuroda, Masaki Hashimoto 1, Seiji Matsumoto 1, Takashi Yokoi 2, Kozo Kuribayashi, Takashi Kijima, Seiki Hasegawa Abstract Background: Limited options exist for treating post-recurrence patients with malignant pleural mesothelioma (MPM). This study aimed to evaluate the efficacy and feasibility […]

Comments Off on Initial Evaluation of Nivolumab in Patients With Post-Operative Recurrence of Malignant Pleural Mesothelioma

The Hippo Pathway as a Driver of Select Human Cancers

Trends Cancer 2020 May 20 [Link] Aishwarya Kulkarni, Matthew T Chang, Joseph H A Vissers, Anwesha Dey, Kieran F Harvey Abstract The Hippo pathway regulates myriad biological processes in diverse species and is a key cancer signaling network in humans. Although Hippo has been linked to multiple aspects of cancer, its role in this disease […]

Comments Off on The Hippo Pathway as a Driver of Select Human Cancers

ERS/ESTS/EACTS/ESTRO Guidelines for the Management of Malignant Pleural Mesothelioma

European Journal of Cardiothoracic Surgery 2020 May 25 [Link] Isabelle Opitz, Arnaud Scherpereel, Thierry Berghmans, Ioannis Psallidas, Markus Glatzer, David Rigau, Philippe Astoul, Servet Bölükbas, Jeanette Boyd, Johan Coolen, Charlotte De Bondt, Dirk De Ruysscher, Valerie Durieux, Corinne Faivre-Finn, Dean A Fennell, Francoise Galateau-Salle, Laurent Greillier, Mir Ali Hoda, Walter Klepetko, Aude Lacourt, Phil McElnay, […]

Comments Off on ERS/ESTS/EACTS/ESTRO Guidelines for the Management of Malignant Pleural Mesothelioma

Metformin-loaded Chitosomes for Treatment of Malignant Pleural Mesothelioma – A Rare Thoracic Cancer

International Journal of Biological Macromolecules 2020 May 20 [Link] Snehal K Shukla, Amanda Chan, Vineela Parvathaneni, Vivek Gupta Abstract The purpose of this study was to design and evaluate chitosan dispersed lipid vesicles (chitosomes) as potential delivery carriers for repurposing metformin (Met) against malignant pleural mesothelioma. Chitosomes were prepared by directly hydrating the thin lipid […]

Comments Off on Metformin-loaded Chitosomes for Treatment of Malignant Pleural Mesothelioma – A Rare Thoracic Cancer

Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response

Cancers 2020 May 19 [Link] Natalia Trempolec, Charline Degavre, Bastien Doix, Davide Brusa, Cyril Corbet, Olivier Feron Abstract For poorly immunogenic tumors such as mesothelioma there is an imperious need to understand why antigen-presenting cells such as dendritic cells (DCs) are not prone to supporting the anticancer T cell response. The tumor microenvironment (TME) is […]

Comments Off on Acidosis-Induced TGF-β2 Production Promotes Lipid Droplet Formation in Dendritic Cells and Alters Their Potential to Support Anti-Mesothelioma T Cell Response