Therapeutic Advances in Urology 2020 December 10 [Link] Özgül Düzgün, Murat Kalın, Resul Sobay, Ömer Faruk Özkan Abstract Background: Urinary system resections and reconstructions are needed in peritoneal carcinomatosis due to abdominal malignancies. The effect of hyperthermic intraperitoneal chemotherapy on these urological procedures after reconstruction remains uncertain. The aim of the study is to evaluate…

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Diagnostic Cytopathology 2020 December 21 [Link] Ashley Re, David Shersher, Ashleigh Allen, Roland Schwarting, Shuyue Ren Abstract Malignant mesothelioma, a neoplasm arising within the serosal surfaces, has been linked closely to asbestos exposure. We present a case of 72-year-old male with a 27 year work-related history of asbestos exposure who presented with dyspnea. Chest computed…

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Clinical Chemistry 2020 December 18 [Link] Kai Bartkowiak, Swaantje Casjens, Antje Andreas, Lucija Ačkar, Simon A Joosse, Irina Raiko, Thomas Brüning, Maria Geffken, Sven Peine, Georg Johnen, Daniel Gilbert Weber, Klaus Pantel Abstract Background: Detection of asbestos-associated diseases like asbestosis or mesothelioma is still challenging. We sought to improve the diagnosis of benign asbestos-associated disease…

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European Journal of Cancer 2020 December 13 [Link] Luca Cantini, Federica Pecci, Daan P Hurkmans, Robert A Belderbos, Andrea Lanese, Cecilia Copparoni, Sophie Aerts, Robin Cornelissen, Daphne W Dumoulin, Ilaria Fiordoliva, Silvia Rinaldi, Joachim G J V Aerts, Rossana Berardi Abstract Background: In preclinical models, statins showed vaccine adjuvant activities and synergized with PD-1 inhibitors.…

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Frontiers in Oncology 2020 November 13 [Link] Olivia Lauk, Karina Bruestle, Thomas Neuer, Bianca Battilana, Thi Dan Linh Nguyen, Thomas Frauenfelder, Rolf Stahel, Walter Weder, Alessandra Curioni-Fontecedro, Isabelle Opitz Abstract Objectives: Adding bevacizumab, an anti-Vascular Endothelial Growth Factor (VEGF), to platinum-based chemotherapy/pemetrexed in 1st line treatment of advanced malignant pleural mesothelioma (MPM), significantly improved overall…

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Investigational New Drugs 2020 December 9 [Link] Irene Dell’Anno, Sarah A Martin, Marcella Barbarino, Alessandra Melani, Roberto Silvestri, Maria Bottaro, Elisa Paolicchi, Alda Corrado, Monica Cipollini, Ombretta Melaiu, Antonio Giordano, Luca Luzzi, Federica Gemignani, Stefano Landi Abstract Objectives Malignant pleural mesothelioma (MPM) is an occupational disease mainly due to asbestos exposure. Effective therapies for MPM…

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Annals of Surgery 2020 December 3 [Link] Moshe Lapidot, Ritu R Gill, Emanuele Mazzola, Samuel Freyaldenhoven, Scott J Swanson, Michael T Jaklitsch, David J Sugarbaker, Raphael Bueno Abstract Objective: We report a series of 355 consecutive patients treated over 9 years in a single institution with intended PDC. Background: Surgery for MPM has shifted from…

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Pathology 2020 November 30 [Link] Eltjona Rrapaj, Lorenzo Giacometti, Paolo Spina, Michela Salvo, Guido Alessandro Baselli, Claudia Veggiani, Ottavio Rena, Elena Trisolini, Renzo Luciano Boldorini Abstract Malignant pleural mesothelioma (MPM) is often associated with a poor prognosis and options for the treatment of this disease are few. To date, the important role of the immune…

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Annals of Thoracic Surgery 2020 December 1 [Link] R Taylor Ripley, Nihanth Palivela, Shawn S Groth, Eugene A Choi, Lorraine D Cornwell, Phillip W Carrott, George Van Buren, Taylor G Splawn, David J Sugarbaker, Bryan M Burt Abstract Background: With a multimodal treatment strategy, cytoreductive surgery extends survival in malignant pleural mesothelioma. Improving the accuracy…

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