Extrapleural Pneumonectomy (EPP)
Surgery for pleural mesothelioma, when it is indicated and why: arguments against surgery for malignant pleural mesothelioma.
Translational Lung Cancer Research 2020 February [Link] Woodard GA, Jablons DM Abstract Extrapleural pneumonectomy (EPP) and pleurectomy decortication (PD) are radical operations for malignant pleural mesothelioma (MPM) that remain controversial among thoracic surgeons. There is a lack of randomized evidence to support a survival benefit when major surgical resection is included in multi-modality treatment regimens.…
Read MoreThe mTOR Signaling Pathway Is Associated With the Prognosis of Malignant Pleural Mesothelioma After Multimodality Therapy.
Anticancer Research 2019 November [Link] Kuroda A, Matsumoto S, Fukuda A, Nakamichi T, Nakamura A, Hashimoto M, Takuwa T, Kondo N, Tsujimura T, Nakano T, Hasegawa S Abstract BACKGROUND/AIM: We performed multimodality therapy comprising preoperative chemotherapy, extrapleural pneumonectomy (EPP), and radiation therapy for patients with malignant pleural mesothelioma (MPM). Although multimodality therapy resulted in good…
Read MoreExtrapleural pneumonectomies for pleural mesothelioma.
Expert Review of Respiratory Medicine 2019 November 1 [Link] Faccioli E, Bellini A, Mammana M, Monaci N, Schiavon M, Rea F Abstract Introduction: Malignant pleural mesothelioma (MPM) is a fatal malignancy for which there is no definitive cure. The most effective multimodality treatment in prolonging survival is still matter of debate. Surgery remains one of…
Read MoreTypes of surgery post-neoadjuvant chemotherapy for pleural mesothelioma.
Expert Review of Respiratory Medicine 2019 October 9 [Link] Kuribayashi K, Doi H, Kijima T Abstract Introduction: The surgical arm of the Mesothelioma and Radical Surgery (MARS) trial involved a multimodal approach, with combined therapy consisting of chemotherapy, complete gross resection, and radiation therapy. However, the MARS trial did not compare surgery with chemotherapy, and…
Read MoreHeterologous sarcomatoid pleural mesothelioma with osteosarcomatous differentiation: a report of autopsy case that accomplished trimodality therapy and review of the literature.
General Thoracic and Cardiovascular Therapy 2019 August 1 [Link] Itano H, Takeda T, Yamada T, Koide M, Kobayashi T Abstract Heterologous mesothelioma is a very rare subtype of sarcomatoid mesothelioma characterized by the presence of malignant heterologous elements. A 69-year-old man with a strong history of asbestos exposure presented with a 5-cm mass in his…
Read MoreExtra-pleural pneumonectomy.
Journal of Thoracic Disease 2019 March [Link] Duranti L, Pardolesi A, Bertolaccini L, Tavecchio L, Scanagatta P, Rolli L, Pastorino U Abstract The extra-pleural pneumonectomy (EPP) is a standardised surgical procedure born for pleural tuberculosis and later used in pleural cancer treatment, especially in malignant pleural mesothelioma (MPM). This systematic review aimed to focus on…
Read MoreExtra-pleural pneumonectomy in the era of image-guided intensity-modulated radiotherapy.
La Radiologia Medica 2019 April 8 [Link] Trovo M, Franceschini D, Furlan C, Pietrobon F, Vagge S, Farina E, Revelant A, Visani L, Maragna V, Parisi G, Scotti V Abstract PURPOSE: To assess the outcome of malignant pleural mesothelioma patients treated with extra-pleural pneumonectomy (EPP) and adjuvant radiotherapy (RT), using the most advanced radiotherapeutic techniques,…
Read MoreHyperthermic Intrathoracic Chemotherapy (HITHOC) for Pleural Malignancies-Experience from Indian Centers.
Indian Journal of Surgical Oncology 2019 February [Link] Patel MD, Damodaran D, Rangole A, Shaikh S, Shah K, Bagwade R, Bhatt A Abstract Hyperthermic intrathoracic chemotherapy (HITHOC) has been used in addition to radical surgery for primary and secondary pleural malignancies to improve local control, prolong survival, and improve the quality of life. This study was…
Read MoreProlonged post-recurrence survival following pleurectomy/decortication for malignant pleural mesothelioma.
Oncology Letters 2019 March [Link] Kai Y, Tsutani Y, Tsubokawa N, Ito M, Mimura T, Miyata Y, Okada M Abstract The present study analyzed surgical results in patients with malignant pleural mesothelioma (MPM) who underwent extrapleural pneumonectomy (EPP) or pleurectomy/decortication (P/D). Data for 44 patients who achieved macroscopic complete resection following neoadjuvant chemotherapy followed by…
Read MoreThe Role of Adjuvant Radiotherapy in the Treatment of Pleural Mesothelioma.
Annals of Surgical Oncology 2019 February 24 [Link] Lewis GD, Dalwadi SM, Farach A, Brian Butler E, Teh BS Abstract BACKGROUND: Pleural mesothelioma is a rare but aggressive form of cancer. Local recurrence represents the majority of treatment failures and overall survival (OS) outcomes remain dismal. Adding locoregional treatment with radiotherapy after surgical resection has…
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