Extrapleural Pneumonectomy (EPP)
The Role of Adjuvant Radiotherapy in the Treatment of Pleural Mesothelioma.
Annals of Surgical Oncology 2019 February 24 [Link] Lewis GD, Dalwadi SM, Farach A, Brian Butler E, Teh BS Abstract BACKGROUND: Pleural mesothelioma is a rare but aggressive form of cancer. Local recurrence represents the majority of treatment failures and overall survival (OS) outcomes remain dismal. Adding locoregional treatment with radiotherapy after surgical resection has…
Read MoreSystematic review of quality of life following pleurectomy decortication and extrapleural pneumonectomy for malignant pleural mesothelioma.
BMC Cancer 2018 November 29 [Link] Schwartz RM, Lieberman-Cribbin W, Wolf A, Flores RM, Taioli E Abstract BACKGROUND: Few studies have focused on quality of life (QoL) after treatment of malignant pleural mesothelioma (MPM). There are still questions as to which surgical procedure, extrapleural pneumonectomy (EPP) or pleurectomy decortication (P/D) is most effective and results…
Read MoreA randomized phase II study of pleurectomy/decortication preceded or followed by (neo-)adjuvant chemotherapy in patients with early stage malignant pleural mesothelioma (EORTC 1205).
Translational Lung Cancer Research 2018 October [Link] Raskin J, Surmont V, Cornelissen R, Baas P, van Schil PEY, van Meerbeeck JP Abstract Radical multimodality treatment for malignant pleural mesothelioma (MPM) is controversial, with intense debate (but lack of data) about which surgical procedure to perform [extrapleural pneumonectomy (EPP) or pleurectomy/decortication (PD)], if any. In order…
Read MoreMultimodality treatment of malignant pleural mesothelioma.
F1000Research 2018 October 22 [Link] Berzenji L, Van Schil P Abstract Malignant pleural mesothelioma (MPM) is a rare disease of the pleura and is largely related to asbestos exposure. Despite recent advancements in technologies and a greater understanding of the disease, the prognosis of MPM remains poor; the median overall survival rate is about 6…
Read MoreUpdated meta-analysis of survival after extrapleural pneumonectomy versus pleurectomy/decortication in mesothelioma.
General Thoracic and Cardiovascular Surgery 2018 October 29 [Link] Magouliotis DE, Tasiopoulou VS, Athanassiadi K Abstract OBJECTIVE: We reviewed the available literature on patients with MPM undergoing either extrapleural pneumonectomy (EPP) or pleurectomy/decortication (P/D). METHODS: Original research studies that evaluated long-term outcomes of P/D versus EPP were identified, from January 1990 to July 2018. The…
Read MoreShort-term outcomes of pleurectomy decortication and extrapleural pneumonectomy in mesothelioma.
Journal of Surgical Oncology 2018 October 7 [Link] van Gerwen M, Wolf A, Liu B, Flores R, Taioli E Abstract BACKGROUND/OBJECTIVES: We evaluated postoperative mortality and complications after extrapleural pneumonectomy (EPP) and pleurectomy decortication (P/D) to better understand their effectiveness in malignant pleural mesothelioma (MPM). METHODS: A meta-analysis was done to evaluate 30-day mortality and…
Read MoreIntensity-modulated radiotherapy is a safe and effective treatment for localized malignant pleural mesothelioma.
Thoracic Cancer 2018 September 21 [Link] Simon M, Shochat T, Peled N, Zer A, Kramer MR, Eldan O, Saute M, Dudnik ER, Allen AM Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare disease and management of localized disease is controversial. Radiotherapy has been shown to be useful after extrapleural pneumonectomy (EPP), as well as…
Read MoreEarly-stage Clinical Characterization of Malignant Pleural Mesothelioma.
In Vivo 2018 September-October [Link] Negi Y, Kuribayashi K, Funaguchi N, Doi H, Mikami K, Minami T, Takuwa T, Yokoi T, Hasegawa S, Ki Abstract BACKGROUND/AIM: A strategy for improving survival of malignant pleural mesothelioma (MPM) patients is earlier diagnosis paired with earlier stage implementation of therapeutic interventions. This study aimed to determine the clinical…
Read MoreFacility volume and postoperative outcomes for malignant pleural mesothelioma: A National Cancer Data Base analysis
Lung Cancer June 2018 [Link] Verma V, Ahern CA, Berlind CG, Lindsay WD, Grover S, Culligan MJ, Friedberg JS, Simone CB Abstract PURPOSE: This study of a large, contemporary national database evaluated postoperative outcomes and overall survival (OS) for malignant pleural mesothelioma (MPM) by facility volume. METHODS: The National Cancer Database was queried for newly-diagnosed…
Read MorePoor Prognostic Factors in Patients with Malignant Pleural Mesothelioma Classified as Pathological Stage IB According to the Eighth Edition TNM Classification
Annals of Surgical Oncology 2018 April 3 [Epub ahead of print] [Link] Takuwa T, Hashimoto M, Kuroda A, Nakamura A, Nakamichi T, Fukuda A, Matsumoto S, Kondo N, Hasegawa S Abstract INTRODUCTION: The change in TNM classification of malignant pleural mesothelioma (MPM) between the seventh and eighth edition classifications has resulted in the downstaging of…
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