Association between asbestos exposure and pericardial and tunica vaginalis testis malignant mesothelioma: a case-control study and epidemiological remarks.

Scandinavian Journal of Work and Environmental Health 2020 April 7 [Link] Marinaccio A, Consonni D, Mensi C, Mirabelli D, Migliore E, Magnani C, Di Marzio D, Gennaro V, Mazzoleni G, Girardi P, Negro C, Romanelli A, Chellini E, Grappasonni I, Madeo G, Romeo E, Ascoli V, Carrozza F, Angelillo IF, Cavone D, Tumino R, Melis…

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Lung Asbestos Fibre Burden and Pleural Mesothelioma in Women with Non-occupational Exposure.

Annals of Work Exposure and Health 2020 February 17 [Link] Barbieri PG, Somigliana A, Chen Y, Consonni D, Vignola R, Finotto L Abstract BACKGROUND: Malignant pleural mesothelioma (MPM) due to environmental and familial (domestic) asbestos exposure is well recognized. However, information on cumulative asbestos dose in subjects affected by MPM is limited. OBJECTIVES: To evaluate…

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Follow-Up of the Libby, Montana Screening Cohort: A 17-Year Mortality Study.

Journal of Occupational and Environmental Medicine 2019 November 8 [Link] Larson TC, Williamson L, Antao VC Abstract OBJECTIVE: To evaluate mortality patterns among participants in a community-based screening program for asbestos-related disease. METHODS: We calculated standardized mortality ratios (SMRs) and stratified results by exposure group (three occupational exposure groups, household contacts and residents without occupational…

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Malignant Mesothelioma: Has Anything Changed?

Seminars in Respiratory and Critical Care Medicine 2019 June [Link] Kim RY1, Sterman DH2, Haas AR3 Abstract Malignant pleural mesothelioma is a rare cancer associated with asbestos exposure and portends a dismal prognosis. Its worldwide incidence has been increasing, and treatment options are currently suboptimal and noncurative. However, since the turn of the century, several…

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Multi-antigen Vaccination With Simultaneous Engagement of the OX40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models.

Frontiers in Oncology 2019 August 2 [Link] Hoffmann PR, Hoffmann FW, Premeaux TA, Fujita T, Soprana E, Panigada M, Chew GM, Richard G, Hindocha P, Menor M, Khadka VS, Deng Y, Moise L, Ndhlovu LC, Siccardi A, Weinberg AD, De Groot AS, Bertino P Abstract Malignant Mesothelioma (MM) is a rare and highly aggressive cancer…

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Chrysotile fibers in tissue adjacent to laryngeal squamous cell carcinoma in cases with a history of occupational asbestos exposure.

Modern Pathology 2019 August 5 [Link] Wronkiewicz SK, Roggli VL, Hinrichs BH, Kendler A, Butler RA, Christensen BC, Marsit CJ, Nelson HH, McClean MD, Kelsey KT, Langevin SM Abstract Asbestos describes a group of naturally occurring fibrous silicate mineral compounds that have been associated with a number of respiratory maladies, including mesothelioma and lung cancer.…

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Environmental and Occupational Exposure to Asbestos as a Result of Consumption and Use in Poland.

International Journal of Environmental Research and Public Health 2019 July 22 [Link] Krówczyńska M, Wilk E Abstract Asbestos is harmful to human health; exposure to asbestos causes a wide range of asbestos-related diseases. AIM: Malignant mesothelioma (MM) is unique to occupational and environmental asbestos exposure. METHODS: Environmental asbestos exposure was examined in relation to asbestos…

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Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits Libby amphibole fiber-induced acute inflammation in mice.

Toxicology and Applied Pharmacology 2019 April 22 [Link] Christofidou-Solomidou M, Pietrofesa RA, Park K, Albelda SM, Serve KM, Keil DE, Pfau JC Abstract BACKGROUND: Exposure to the Libby Amphibole (LA) asbestos-like fibers found in Libby, Montana, is associated with inflammatory responses in mice and humans, and an increased risk of developing mesothelioma, asbestosis, pleural disease,…

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