Case Study
Second line therapy in malignant pleural mesothelioma: A systematic review
Lung Cancer 2015 June 23 [Epub ahead of print] [Link] Buikhuisen WA, Hiddinga BI, Baas P, van Meerbeeck JP. Abstract After the implementation of standard first line chemotherapy with platinum and antifolates in pleural mesothelioma, patients are confronted with a need for second line treatment at relapse or progression. We conducted a systematic review of…
Read MoreMalignant Mesothelioma Diagnosed by Bronchoscopic Biopsy
Tuberculosis and Respiratory Diseases 2015 July [Link] Park YH, Choi JW, Jung SO, Cho MJ, Kang DH, Chung CU, Park DI, Moon JY, Park HS, Jung SS, Kim JO, Kim SY, Lee JE. Abstract Malignant mesothelioma is a rare malignant neoplasm that arises from mesothelial surfaces of the pleural cavity, peritoneal cavity, tunica vaginalis, or…
Read MoreALK Translocation in Paediatric Malignant Peritoneal Mesothelioma: A Case Report of Novel ALK-Related Tumour Spectrum
Histopathology 2015 July 14 [Epub ahead of print] [Link] Loharamtaweethong K, Puripat N, Aoonjai N, Sutepvarnon A, Bandidwattanawong C. Abstract Aims To report a case of paediatric malignant peritoneal mesothelioma (MPM) with evidence of anaplastic lymphoma kinase (ALK) translocation. Materials and Results We describe a 10-year-old girl who presented with abdominal pain and progressive abdominal…
Read MoreCerebral Metastasis of a Malignant Pleural Mesothelioma: A Case Report and Review of the Literature
Cureus 2015 January 15 [Link] Chari A, Kolias AG, Allinson K, Santarius T. Abstract Background Malignant pleural mesothelioma (MPM) is an aggressive malignant neoplasm that was thought to be a localised disease with limited metastatic capability. However, recent post-mortem studies have identified metastases to the central nervous system (CNS) in about 3% of cases. Case…
Read MoreComparing the results of pathologic diagnosis of mesothelioma between Chinese and Japanese experts
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2015 January [Link] Lou J, Gao Z, Jiang Z, Chen J, Chen R, Zhang X. Abstract Objective To compare the results of pathological diagnosis of 41 patients with malignant mesothelioma between Chinese and Japanese experts, and to provide a basis for the standard for diagnosis…
Read MoreAsbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China
American Journal of Industrial Medicine 2015 July 6 [Epub ahead of print] [Link] Gao Z, Hiroshima K, Wu X, Zhang J, Shao D, Shao H, Yang H, Yusa T, Kiyokawa T, Kobayashi M, Shinohara Y, Røe OD, Zhang X, Morinaga K. Abstract Background Chrysotile had been used in asbestos textile workshops in Southeast China but…
Read MoreMalignant mesothelioma in the peritoneal cavity – a case report
Rozhledy v chirurgii 2015 Spring [Link] Rupert K, TÅ™eÅ¡ka V. Abstract Malignant mesothelioma is a rare tumour with an incidence of 0.53 cases per million inhabitants. Only about 20% of cases occur in the peritoneum. The authors use the case report of a male patient with malignant mesothelioma occurring in the peritoneal cavity to demonstrate…
Read MoreResearch priorities in mesothelioma: A James Lind Alliance Priority Setting Partnership
Lung Cancer 2015 June 4 [Epub ahead of print] [Link] Stephens RJ, Whiting C, Cowan K; James Lind Alliance Mesothelioma Priority Setting Partnership Steering Committee. Abstract Background In the UK, despite the import and use of all forms of asbestos being banned more than 15 years ago, the incidence of mesothelioma continues to rise. Mesothelioma…
Read MoreComprehensive Review of BAP1 Tumor Predisposition Syndrome with Report of Two New Cases
Clinical Genetics 2015 June 22 [Epub ahead of print] [Link] Rai K, Pilarski R, Cebulla CM, Abdel-Rahman MH. Abstract The BRCA1 associated protein-1 (BAP1) tumor predisposition syndrome (BAP1-TPDS) is a recently identified hereditary cancer syndrome. Germline mutations in this tumor suppressor gene predispose families to the development of various malignancies. The molecular functions of the…
Read MoreNuclear Brachyury Expression Is Consistent in Chordoma, Common in Germ Cell Tumors and Small Cell Carcinomas, and Rare in Other Carcinomas and Sarcomas: An Immunohistochemical Study of 5229 Cases
American Journal of Surgical Pathology 2015 April 4 [Epub ahead of print] [Link] Miettinen M, Wang Z, Lasota J, Heery C, Schlom J, Palena C. Abstract Brachyury is a transcription factor of the T-box family typically expressed in notochord and chordoma. Some studies report brachyury as highly specific for chordoma, whereas others have concluded that…
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