Case Study
Granulocyte-colony stimulating factor (G-CSF) producing malignant pleural mesothelioma: Report of a case
Thoracic Cancer 2015 January [Link] Fujiwara A, Higashiyama M, Kanou T, Okami J, Tokunaga T, Tomita Y, Kodama K. Abstract This report presents a case of malignant pleural mesothelioma (MPM) producing granulocyte colony-stimulating factor (G-CSF) that was treated by tumor resection. A 76-year-old male presented with a huge right-side chest wall tumor, along with a…
Read MoreAn immunohistochemical comparison of two TTF-1 monoclonal antibodies in atypical squamous lesions and sarcomatoid carcinoma of the lung, and pleural malignant mesothelioma
Journal of Clinical Pathology 2015 August 17 [Epub ahead of print] [Link] Klebe S, Swalling A, Jonavicius L, Henderson DW. Abstract Immunohistochemical detection of thyroid transcription factor-1 (TTF-1) plays an important role in the diagnosis and subclassification of non-small cell carcinomas of the lung in biopsy and some cytology samples, specifically for identification of squamous…
Read MoreIncreased Standardised Incidence Ratio of Malignant Pleural Mesothelioma in Taiwanese Asbestos Workers: A 29-Year Retrospective Cohort Study
BioMed Research International 2015 [Link] Lin CK, Chang YY, Wang JD, Lee LJ. Abstract Objective This paper aimed to determine the standardised incidence ratio (SIR) of malignant pleural mesothelioma (MPM) in workers exposed to asbestos in Taiwan. Methods All workers employed in asbestos-related factories and registered by the Bureau of Labour Insurance between 1 March,…
Read MoreTemsirolimus targets multiple hallmarks of cancer to impede mesothelioma growth in vivo
Respirology 2015 August 5 [Epub ahead of print] [Link] Vazakidou ME, Magkouta S, Moschos C, Psallidas I, Pappas A, Psarra K, Kalomenidis I. Abstract Background and Objective The mechanistic target of rapamycin (mTOR) promotes cancer cell proliferation and survival, transduces pro-angiogenic signals and regulates immune cell differentiation and function. We hypothesized that temsirolimus, an mTOR…
Read MoreFrequent genomic rearrangements of BRCA1 associated protein-1 (BAP1) gene in Japanese malignant mesothelioma-characterization of deletions at exon level
Journal of Human Genetics 2015 August 6 [Epub ahead of print] [Link] Emi M, Yoshikawa Y, Sato C, Sato A, Sato H, Kato T, Tsujimura T, Hasegawa S, Nakano T, Hashimoto-Tamaoki T. Abstract Malignant mesothelioma (MM) is an asbestos-related malignancy arising from surface serosal cells of pleural and peritoneal cavities. Somatic mutations of BRCA1 associated…
Read MoreEctopic ACTH secretion (EAS) associated to a well-differentiated peritoneal mesothelioma: case report
BMS Endocrine Disorders 2015 August 8 [Link] Mendoza CF, Ontiveros P, Xibillé DX, Rivera MH. Abstract Background The association between mesotheliomas and ectopic ACTH secretion has been rarely reported; we present the first case of ectopic ACTH secretion (EAS) associated with a well-differentiated peritoneal mesothelioma in whom the high dose dexamethasone suppression test (HDDST) results…
Read MoreCancer Attributable to Asbestos Exposure in Shipbreaking Workers: A Matched-Cohort Study
PLoS One 2015 July 20 [Link] Wu WT, Lin YJ, Li CY, Tsai PJ, Yang CY, Liou SH, Wu TN. Abstract Purpose Long-term follow-up studies of asbestos-related cancer in shipbreaking workers are lacking. This study examines the relationship between cancer incidence and asbestos exposure among former Taiwan shipbreaking workers. Methods A total of 4,427 shipbreaking…
Read MoreEmerging evidence that the ban on asbestos use is reducing the occurrence of pleural mesothelioma in Sweden
Scandinavian Journal of Public Health 2015 July 20 [Epub ahead of print] [Link] Järvholm B, Burdorf A. Abstract Aims Several countries have banned the use of asbestos. The future health impacts of previous use have been modeled but there are to our knowledge no convincing studies showing a decreased occurrence of asbestos-related diseases due to…
Read MoreDistinctive clinical characteristics of malignant mesothelioma in young patients
Oncotarget 2015 June [Link] Thomas A, Chen Y, Yu T, Gill A, Prasad V. Abstract Although considered a disease of the elderly, a subset of patients with mesothelioma are young (
Read MoreFunctional Alteration of Natural Killer Cells and Cytotoxic T Lymphocytes upon Asbestos Exposure and in Malignant Mesothelioma Patients
BioMed Research International 2015 [Link] Nishimura Y, Kumagai-Takei N, Matsuzaki H, Lee S, Maeda M, Kishimoto T, Fukuoka K, Nakano T, Otsuki T. Abstract Malignant mesothelioma is caused by exposure to asbestos, which is known to have carcinogenic effects. However, the development of mesothelioma takes a long period and results from a low or intermediate…
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