A novel concept of treatment of diffuse or multiple pleural tumors by boron neutron capture therapy (BNCT)

Radiotherapy and Oncology. 2008 Jul 22. [Epub ahead of print] [Link]

Suzuki M, Endo K, Satoh H, Sakurai Y, Kumada H, Kimura H, Masunaga S, Kinashi Y, Nagata K, Maruhashi A, Ono K.

Particle Radiation Oncology Research Center, Research Reactor Institute, Kyoto University, Osaka, Japan.

Abstract

Two patients, one with malignant pleural mesothelioma and one with a malignant short spindle cell tumor, received boron neutron capture therapy (BNCT). In each case, the tumors regressed or remained stable in size for 3–6 months following BNCT. No acute or late adverse events higher than grade 2 were observed.

Keywords: Boron neutron capture therapy, Thoracic tumor, Malignant pleura mesothelioma