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Curated Journal Articles on Mesothelioma

Category Archives: Biomarkers

3-(2-deoxy-β-D-erythro-pentafuranosyl)pyrimido[1,2-α]purin-10(3H)-one deoxyguanosine adducts of workers exposed to asbestos fibers

Toxicology Letters 2017 February 7 [Epub ahead of print] [Link] Bonassi S, Cellai F, Munnia A, Ugolini D, Cristaudo A, Neri M, Milić M, Bonotti A, Giese RW, Peluso ME Abstract Asbestos is the commercial name for a group of silicate minerals naturally occurring in the environment and widely used in the industry. Asbestos exposure […]

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Prognostication and monitoring of mesothelioma using biomarkers: a systematic review

British Journal of Cancer 2017 February 7 [Epub ahead of print] [Link] Arnold DT, De Fonseka D, Hamilton FW, Rahman NM3, Maskell NA Abstract BACKGROUND: Radiological markers of treatment response and prognostication in malignant pleural mesothelioma have limitations due to the morphology of the disease. Serum or pleural fluid biomarkers that could act as an […]

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Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation

Cancer Science 2017 February 9 [Epub ahead of print] [Link] Takeuchi S, Fukuda K, Yamada T, Arai S, Takagi S, Ishii GI, Ochiai A, Iwakiri S, Itoi K, Uehara H, Nishihara H, Fujita N, Yano S Abstract Malignant pleural mesothelioma (MPM) is characterized by dissemination and aggressive growth in the thoracic cavity. Podoplanin (PDPN) is […]

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MUC4, a novel immunohistochemical marker identified by gene expression profiling, differentiates pleural sarcomatoid mesothelioma from lung sarcomatoid carcinoma

Modern Pathology 2017 January 27 [Epub ahead of print] [Link] Amatya VJ, Kushitani K, Mawas AS, Miyata Y, Okada M, Kishimoto T, Inai K, Takeshima Y Abstract Sarcomatoid mesothelioma, a histological subtype of malignant pleural mesothelioma, is a very aggressive tumor with a poor prognosis. Histological diagnosis of sarcomatoid mesothelioma largely depends on the histomorphological […]

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Diagnostic and prognostic utilities of humoral fibulin-3 in malignant pleural mesothelioma: Evidence from a meta-analysis

Oncotarget 2017 January 18 [Epub ahead of print] [Link] Pei D1, Li Y, Liu X, Yan S, Guo X, Xu X, Guo X Abstract Fibulin-3 has emerged as a promising novel biomarker in conforming or monitoring malignant pleural mesothelioma (MPM). This study sought to evaluate the diagnostic and prognostic efficacies of humoral fibulin-3 for MPM. […]

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Usefulness of p16/CDKN2A fluorescence in situ hybridization and BAP1 immunohistochemistry for the diagnosis of biphasic mesothelioma

Annals of diagnostic pathology 2017 Feb [Epub 2016 October 22] [Link] Wu D, Hiroshima K, Yusa T, Ozaki D, Koh E, Sekine Y, Matsumoto S, Nabeshima K, Sato A, Tsujimura T, Yamakawa H, Tada Y, Shimada H, Tagawa M Abstract Malignant mesothelioma is a highly aggressive neoplasm, and the histologic subtype is one of the […]

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Arginine Deprivation With Pegylated Arginine Deiminase in Patients With Argininosuccinate Synthetase 1-Deficient Malignant Pleural Mesothelioma: A Randomized Clinical Trial

JAMA Oncology 2017 January [Link] Szlosarek PW, Steele JP, Nolan L, Gilligan D, Taylor P, Spicer J, Lind M, Mitra S, Shamash J, Phillips MM, Luong P, Payne S, Hillman P, Ellis S, Szyszko T, Dancey G, Butcher L, Beck S, Avril NE, Thomson J, Johnston A, Tomsa M, Lawrence C, Schmid P, Crook T, […]

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BAP1 is altered by copy number loss, mutation, and/or loss of protein expression in more than 70% malignant peritoneal mesotheliomas

Journal of Thoracic Oncology: Official Publication of the International Association for the Study of Lung Cancer 2016 December 27 [Epub ahead of print] [Link] Leblay N, Leprêtre F, Le Stang N, Gautier-Stein A, Villeneuve L, Isaac S, Maillet D, Galateau-Sallé F, Villenet C, Sebda S, Goracci A, Byrnes G, McKay JD, Figeac M, Glehen O, […]

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Malignant pleural mesothelioma: an update on investigation, diagnosis and treatment

European Respiratory Review 2016 December [Link] Bibby AC, Tsim S, Kanellakis N, Ball H, Talbot DC, Blyth KG, Maskell NA, Psallidas Abstract Malignant pleural mesothelioma is an aggressive malignancy of the pleural surface, predominantly caused by prior asbestos exposure. There is a global epidemic of malignant pleural mesothelioma underway, and incidence rates are predicted to […]

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Fluoro-edenite induces fibulin-3 overexpression in non-malignant human mesothelial cells

Oncology Letters 2016 November [Epub 2016 August 26] [Link] Rapisarda V, Salemi R, Marconi A, Loreto C, Graziano AC, Cardile V, Basile MS, Candido S, Falzone L, Spandidos DA, Fenga C, Libra M Abstract Exposure to asbestos is associated with the development of mesothelioma. In addition to asbestos, other fibers have been identified as risk […]

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