Peritoneal (Abdominal Mesothelioma)
The clinicopathological significance of TOP2A expression in malignant peritoneal mesothelioma
Annals of Diagnostic Pathology 2023 August [Link] Xuemei Du, Xinbao Li, Bingdong Zhang, Zechen Hao, Ying Gao, Xi Jiang, Zhiran Yang, Yizhi Chen Abstract Background: Malignant peritoneal mesothelioma (MPM) is a rare malignant tumor with a high mortality rate and extremely poor prognosis. TOP2A expression is associated with cell proliferation and cell cycle progression. We…
Read MoreMetabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma
International Journal of Molecular Sciences 2023 April 24 [Link] Marika A Franczak, Oliwia Krol, Gabriela Harasim, Agata Jedrzejewska, Nadia Zaffaroni, Carlotta Granchi, Filippo Minutolo, Amir Avan, Elisa Giovannetti, Ryszard T Smolenski, Godefridus J Peters Abstract Malignant mesothelioma (MM) is a highly aggressive and resistant tumor. The prognostic role of key effectors of glycolytic metabolism in…
Read MorePrognostic role of CD74, CD10 and Ki-67 immunohistochemical expression in patients with diffuse malignant peritoneal mesothelioma: a retrospective study
BMC Cancer 2023 May 5 [Link] Yufei Liang, Chunying Li, Yingying Liu, Liang Tian, Dongliang Yang Abstract Background: Diagnosis and treatment of diffuse malignant peritoneal mesothelioma (DMPM) are still challenging. The aim of the present study was to explore the correlation between CD74, CD10, Ki-67 and clinicopathological parameters, and identify independent prognostic factors of DMPM.…
Read MorePrognostic significance of the immuno-peritoneal cancer index in peritoneal metastatic patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
Langenbeck’s Archives of Surgery 2023 May 6 [Link] Yasemin Yildirim, Selman Sokmen, Ali Durubey Cevlik, Tayfun Bisgin, Berke Manoglu, Funda Obuz Abstract Purpose: A valid comparison of immune function among different patients with different primary pathologies or even with different tumour burdens requires the common use of a reliable assessment of the patient’s condition. The…
Read MoreGeldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma
PloS One 2023 May 5 [Link] M Lizeth Orozco Morales, Catherine A Rinaldi, Emma de Jong, Sally M Lansley, Y C Gary Lee, Rachael M Zemek, Anthony Bosco, Richard A Lake, W Joost Lesterhuis Abstract Mesothelioma is characterised by its aggressive invasive behaviour, affecting the surrounding tissues of the pleura or peritoneum. We compared an…
Read MoreLncRNAs and related molecular basis in malignant pleural mesothelioma: Challenges and potential
Critical Reviews in Oncology/Hematology 2023 June [Link] Xiaoling Xu, Huihui Li, Mingying Xie, Zichao Zhou, Ding Wang, Weimin Mao Abstract Malignant pleural mesothelioma (MPM) is a rare but invasive cancer, which mainly arises from mesothelial tissues of pleura, peritoneum and pericardium. Despite significant advances in treatments, the prognosis of MPM patients remains poor, and the…
Read MoreComparison of the role of 18 F-fluorodeoxyglucose PET/computed tomography and 68 Ga-labeled FAP inhibitor-04 PET/CT in patients with malignant mesothelioma
Nuclear Medicine Communications 2023 April 28 [Link] Yunus Güzel, Halil Kömek, Canan Can, İhsan Kaplan, Ferat Kepenek, Senar Ebinç, Mehmet Perver Büyükdeniz, Cihan Gündoğan, Zeynep Oruç Abstract Objective: In this study, we aimed to compare the role of 68 Ga-labeled FAP inhibitor ( 68 Ga-FAPI)-04 PET/computed tomography (CT) and 18 F-fluorodeoxyglucose ( 18 F-FDG) PET/CT…
Read MoreAntitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo
Biology Direct 2023 April 17 [Link] Monica Benvenuto, Valentina Angiolini, Chiara Focaccetti, Daniela Nardozi, Camilla Palumbo, Raffaele Carrano, Alessandra Rufini, Riccardo Bei, Martino Tony Miele, Patrizia Mancini, Giovanni Barillari, Mara Cirone, Elisabetta Ferretti, Grazia Raffaella Tundo, Luciano Mutti, Laura Masuelli, Roberto Bei Abstract Background: Malignant mesothelioma (MM) is a rare tumor with a dismal prognosis.…
Read MoreSurgical phenotype of patients with peritoneal mesothelioma and a germline mutation
Cancer 2023 April 12 [Link] Yaniv Berger, Meghana Gadiraju, Ankit Dhiman, Katie Gilliam, Buerkley Opalecky, Heather Chen, Maria Helgeson, Oliver S Eng, Aliya N Husain, Michael W Drazer, Hedy L Kindler, Jane E Churpek, Kiran K Turaga Abstract Background: This study aimed to investigate if peritoneal mesothelioma (PM) patients with germline mutations (GM) have distinct…
Read MoreSurgical case report: The rare case of incidental retroperitoneal mesothelioma
International Journal of Surgery Case Reports 2023 April [Link] Yat Cheung Chung, Travis Ackermann, Yeu Sheng Ang Abstract Introduction and importance: This is a first reported case of isolated retroperitoneal mesothelioma. Most patients present with symptoms of abdominal pain, distension and weight loss. However, a minority of cases are asymptomatic and are found incidentally on…
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