Peritoneal (Abdominal Mesothelioma)
Successful Response to First-Line Carboplatin, Pemetrexed, and Bevacizumab for Peritoneal Mesothelioma: Two Case Reports
Case Reports in Oncology 2025 January 30 [Link] Tomonobu Koizumi, Shintaro Kanda, Nodoka Sekiguchi, Takuro Noguchi, Sei-Ichiro Eda, Hiroto Kitahara Abstract Introduction: Peritoneal mesothelioma is an extremely rare malignancy of the peritoneum. It has a poor prognosis, and the optimal systemic chemotherapy remains controversial. Here, we report two cases of peritoneal mesothelioma with long-term survival…
Read MoreProspective Analysis of Mesotheliomas in Subjects with BAP1 Cancer Syndrome: Clinical Characteristics and Epigenetic Correlates of Disease
Journal of Thoracic Oncology 2025 August 5 [Link] Xinwei Wu, Frank-Villa Hernandez, Haitao Wang, Ruihong Wang, Stephanie Shiffka, Niharika Shah, Shamus R Carr, Chuong D Hoang, Andrew M Blakely, Alexandra Lebensohn, Keerti Mihsra, Sichuan Xi, Mary R Zhang, Tuana Tolunay, Sudheer Gara, Amanda Absher, Deneise Francis, Amanda Rowland, Maureen Connolly, Stephanie Jacobs, Sandra Orfgen, Kevin…
Read MoreNeoadjuvant immunotherapy in a solitary, isolated peritoneal mesothelioma involving the abdominal wall: a case report
Immunotherapy 2025 July [Link] Parsa Charkhchi, Ryan Le, Taryn E Cazzolli, Raina R Flores, Roberto A Martinez, Supreet Kaur, Mio Kitano Abstract Mesothelioma is a rare neoplasm with a minority of cases originating from the peritoneum. Patients are generally treated with a combination of cytoreductive surgery, hyperthermic intraperitoneal chemotherapy, and various systemic therapies. In recent…
Read MoreLong Road to Identifying Peritoneal Mesothelioma: An Elusive Diagnosis
Cureus 2025 June 13 [Link] Thejas Swaroop Konduru, Gourav Gourisaria, Goksu Ozen, Pradeep Karunakaran Thozhuthumparambil Abstract Peritoneal mesothelioma is a rare and aggressive malignancy that often presents with non-specific abdominal symptoms such as ascites, leading to delayed diagnosis and treatment. It poses significant diagnostic challenges, especially in the absence of classical risk factors like asbestos…
Read MoreA giant peritoneal mesothelioma extending to the pelvic floor: A case report and review of the literature
Journal of Cancer Research and Therapeutics 2025 April 1 [Link] Mathew Thomas, Harikrishnan Nandakumar, Parth Sampat, Stephen Graziano Abstract Malignant peritoneal mesothelioma (MPM) is a rare malignancy originating from the peritoneal serosa and is the second most common site of mesothelioma after the pleura. Localized disease presents as a focal circumscribed mass, whereas diffuse disease…
Read MoreClinical and Pathologic Phenotyping of mesotheliomas developing in carriers of Germline BAP1 Mutations
Journal of Thoracic Oncology 2025 June 27 [Link] Michele Carbone, Michael Minaai, Muaiad Kittaneh, Thomas Krausz, Markku M Miettinen, Qiang Pan Hammarström, Lennart Hammarström, Hassan Abolhassani, Ian Pagano, Ronghui Xu, Flavia Novelli, Giovanni Gaudino, Sandra Pastorino, Kavita Y Sarin, Robert T Ripley, Harvey I Pass, David S Schrump , Haining Yang Abstract Introduction: Mesothelioma is…
Read MoreImmune Composition and Immunotherapy Outcomes of Mesothelioma with BAP1, CDKN2A, MTAP, and NF2 Alterations
Journal of Thoracic Oncology 2025 June 25 [Link] Ibiayi Dagogo-Jack, Owen Mitchell, Elizabeth Codd, Annie Li, Dawn Mitchell, Samantha E Flynn, Nanna Sivamanoharan, Patrick Reeves, Mark Poznansky, Ivan Valiev, Artem Kosmin, Beow Y Yeap, Grace Hambelton, A John Iafrate, Jochen K Lennerz, Yin P Hung, Hedy Kindler Abstract Background: First-line mesothelioma treatment paradigms prioritize histology…
Read MoreLoss of MTAP expression is not an accurate surrogate for CDKN2A homozygous deletions in peritoneal mesothelioma
Histopathology 2025 June 25 [Link] Andrea Quaranta, Andrea Marzullo, Francesco Fortarezza, Sonia Maniglio, Concetta Caporusso, Floriana Pentimone, Federica Pezzuto, Domenica Cavone, Teresa Lettini, Mario Magistro, Cecilia Salzillo, Luigi Vimercati, Paolo Graziano, Gabriella Serio, Antonio d’Amati Abstract Aims: Mesothelioma is a malignant neoplasm of the serosal membranes originating from mesothelial cells. Peritoneal mesothelioma is the second…
Read MoreCharacteristics of Long-Term Survivors With Peritoneal Mesothelioma – Insights From the National Cancer Database
The American Surgeon 2025 June 17 [Link] Himani Bhatt, Deep P Vakil, Luis Quintero, Monique Motta, Maria Vashchenko, Bettsy Rodriguez, Shenae K Samuels, Kumar Jayant, Jonathan Magloire, Christopher J Gannon, Omar H Llaguna Abstract Introduction: Peritoneal mesothelioma (PM) is a rare cancer associated with high mortality. No studies exist using the National Cancer Database (NCDB)…
Read MoreMalignant mesothelioma with a novel BAP1 germline frameshift mutation treated with dual immune checkpoint inhibitors: A case report
Oncology Letters 2025 May 21 [Link] Na Zhou, Mingying Wu, Chenyu Wang, Mingming Yuan, Yuejuan Cheng Huanwen Wu, Xin Gao, Shuangni Yu, Lin Zhao Abstract Germline pathogenic mutation of the BAP1 gene is a common molecular event in malignant mesothelioma (MM). A patient with a positive family history of tenacious peritoneal effusions presented with hydropneumothorax…
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